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Background: Accurate risk/outcome prediction, in which molecular signatures (MS) are playing an increasingly important role, is crucial for personalized therapy. Patients require an accurate diagnosis and an appropriate ...

Intense training refers to training mediated by emotionally arousing experiences, such as aversive conditioning motivated by relatively high intensities of foot-shock, which produces a strong memory that is highly resist...

Our understanding of the synthesis and remodeling of mitochondrial phospholipids remains incomplete. Two isoforms of glycerol-3-phosphate acyltransferase (GPAT1 and 2) and two isoforms of acylglycerol-3-phosphate acyltra...

Tamoxifen is a standard endocrine therapy for estrogen receptor positive breast cancer patients. Despite its success,development of resistance mechanisms is still a serious clinical problem. Deregulation of survival sign...

Parkinson’s disease (PD) is the second most common neurodegenerative disorder related with aging. The death of dopaminergic neurons triggered by oxidative stress and mitochondrial dysfunction is one pathognomonic chara...