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Evaluating the Predictive Power of Cognitive Assessment Tools for Cortical Hypometabolism in Alzheimer’s Disease

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Evaluating the Predictive Power of Cognitive Assessment Tools for Cortical Hypometabolism in Alzheimer’s Disease

Mohammad Sadeghi et al · Shiraz University of Medical Sciences · 2025 · ISSN 2345-6167

Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by memory loss and cognitive decline. One of the leading theories explaining AD pathology is the emergence of cortical hypo...

LCC LCC:Therapeutics. PharmacologyIdioma eng

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Post-mortem human Alzheimer´s brain metallome depends on Braak stages and brain regions

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Post-mortem human Alzheimer´s brain metallome depends on Braak stages and brain regions

Cecilio Parra-Martínez et al · Nature Portfolio · 2025 · ISSN 2045-2322

Abstract Limited studies have evaluated the influence of redox-related metals on the Alzheimer´s brain. We determined 15 metals in 241 human brain samples obtained from five biobanks. We examined the levels of metals in...

LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng

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RETRACTED ARTICLE: A novel approach integrating topological deep learning from EEG Data in Alzheimer’s disease

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RETRACTED ARTICLE: A novel approach integrating topological deep learning from EEG Data in Alzheimer’s disease

Miriam Esteve et al · Nature Portfolio · 2025 · ISSN 2045-2322

Abstract High-throughput analysis of EEG data has significantly contributed to understanding neural dynamics in Alzheimer’s disease diagnosis. However, the complexity and high dimensionality of EEG signals pose challen...

LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng

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Exercise-induced neurogenesis through BDNF-TrkB pathway: implications for neurodegenerative disorders

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Exercise-induced neurogenesis through BDNF-TrkB pathway: implications for neurodegenerative disorders

Lee Jun Jie et al · De Gruyter · 2025 · ISSN 2942-6812

Current scientific endeavours in the field of geroscience have begun to reveal how factors such as exercise could modulate the brain aging process. In this review, we ask how exercise could potentially modulate aging, an...

LCC LCC:Medicine; TENDOlNwb3J0cw~~Idioma eng

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DNA methylation signatures of Life’s Essential 8 and their implications for dementia

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DNA methylation signatures of Life’s Essential 8 and their implications for dementia

David Lukacsovich et al · BMC · 2025 · ISSN 1758-9193

Abstract Background As dementia cases continue to rise, effective prevention strategies are urgently needed. However, objective biomarkers that directly reflect lifestyle factors remain limited. Life’s Essential 8 (LE8...

LCC LCC:Neurosciences. Biological psychiatry. Neuropsychiatry; LCC:Neurology. Diseases of the nervous systemIdioma eng

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