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Abstract A decrease in resting muscle O2 uptake (V̇O2m) described during bed rest (BR) could determine a decreased whole‐body resting energy expenditure (REE), potentially useful during prolonged spaceflights. Two gro...

IntroductionSkin cancer, including basal cell carcinoma, squamous cell carcinoma, and melanoma, is one of the most common cancers worldwide. Matrix metalloproteinases are zinc-dependent proteolytic enzymes that play a cr...

Abstract Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The Biobanking and Biomolecular Resources European Research Infrastructure (BBMRI-ERIC) established a CRC-Cohort with European cover...

Abstract In a previous scientific opinion on application EFSA‐GMO‐BE‐2016‐138, the EFSA Panel on Genetically Modified Organisms (GMO Panel) could not conclude on the comparative analysis and on the food and feed ...

The WHO estimates that by 2050, 70% of the global population will reside in urban areas—centers of opportunity but also major health risks. Urbanization contributes to the rise of non-communicable chronic diseases, lin...

Objective To synthesize the available evidence on the effects of constraint-induced movement therapy (CIMT) in children with hemiplegic cerebral palsy (CP), focusing on upper limb functional outcomes and neuroplasticity-...

Abstract Large Language Models (LLMs) and Retrieval-Augmented Generation (RAG) systems have significantly advanced data modelling capabilities and improved opportunities for extracting knowledge from vast and heterogeneo...

Abstract Background Biallelic SPG7 mutations cause one of the most common forms of hereditary spastic paraplegia (HSP). Several reports have suggested that heterozygous SPG7 variants may also play a role in HSP, but also...

IntroductionAlthough sports participation is recognized for its psychological benefits, it remains unclear whether participation in competitive sports may produce different effects on these symptoms among sexual minority...

Abstract BackgroundThe integration of robots into industrial settings has rapidly advanced, aiming to reduce human involvement in demanding tasks while improving overall efficiency. As collaborative robots (c...

Objective To assess the effectiveness of belimumab (BEL) in improving anaemia, thrombocytopenia, lymphopenia and leucopenia in patients with SLE.Methods The BeRLiSS (Belimumab in Real Life Setting Study) 2.0 cohort inclu...

The development of efficient nonstoichiometric redox materials for solar-driven H₂O/CO₂ splitting via two-step thermochemical cycles requires optimization of redox thermodynamics, kinetics, and material stability. Th...

Abstract Background Children with Unilateral Cerebral Palsy (UCP) are characterized by significant upper limbs (ULs) impairment that hinders daily activities and participation, requiring accurate assessment. Although mot...

Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD), the most prevalent cause of chronic liver disease worldwide, currently lacks precision medicine treatments. SLCO4C1 acts as a transporter for end...

European rural regions are of immense significance to agricultural production, tourism, as well as the preservation of nature, but are highly inadequately served with regard to transport infrastructure, thereby contribut...

Creatine kinase (CK) is an enzyme that plays a pivotal role in various physiological processes, including metabolism and muscle function. This enzyme is found in high concentrations in skeletal muscle and the myocardium,...

Abstract Background Tauopathies are a group of neurodegenerative diseases, including Alzheimer’s disease (AD), characterized by progressive accumulation of pathological Tau proteins. Among the diverse Tau species, trun...

ABSTRACT Atomic‐scale control of oxide–ferromagnet interfaces is crucial for optimizing spintronic heterostructures, yet interfacial oxygen remains difficult to control and verify. Here, we deterministically tune the...

ABSTRACT Background and Aims In liver disease (LD), multidisciplinary teams (MDTs) support complex decision‐making and may improve care delivery. The present study aims to evaluate the role of a multidisciplinary appro...

Abstract Background Prone positioning is recommended for patients with acute respiratory distress syndrome not only to improve oxygenation, but also to reduce lung stress, and lower mortality. The association between imp...

BackgroundStroke remains a primary cause of long-term disability worldwide, with upper-limb deficits affecting up to 80% of survivors acutely and 40% chronically. These deficits lead to considerable effects on their inde...