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Oral mucosal ageing represents a fundamental reprogramming of the tissue microenvironment, a dynamic process that underlies the functional decline and heightened disease susceptibility observed in the elderly. This revie...

Abstract Background Adverse events across the lifespan have been linked to poorer health outcomes, but the biological mechanisms remain unclear. The aim of this study was to quantify the independent and joint association...

Abstract Background Healthy ageing encompasses maintaining optimal physical, psychological, social, and cognitive well-being across the lifespan. While age-specific needs are widely acknowledged, many studies aggregate a...

Ageing is a complex biological process marked by gradual functional decline, reduced cellular resilience, and increased vulnerability to chronic diseases. Maintaining cell health has become a crucial strategy for extendi...

Abstract Objectives DNA methylation (DNAm) can change dynamically in response to intrinsic or external exposures. Characteristic methylation profiles are associated with accelerated biological ageing and poorer health ou...

This study evaluated the ameliorative effect of dietary inclusion of lemongrass infusions in D-galactose-induced ageing in Drosophila melanogaster. The flies were randomized into 5 groups comprising Control (fed on a nor...

The ageing of the society is a serious factor affecting the prospects of urban development. Unfavourable demographic changes disturb the functioning of the urban system, thus forcing adaptive activities leading to a new ...

Abstract Background Ageism among healthcare professionals can undermine the quality of care for older adults, particularly those with high support needs in long-term care. Undergraduate dental curricula often provide lim...

Abstract A growing body of evidence supports the role of nutrient sensing and metabolism pathways in regulating ageing rate and healthspan, but the diversity of human lifestyles challenges our ability to identify the mec...

Polish population is getting older and the consequences of this process are already affecting our everyday life. The purpose of this work is to identify factors (and direction of their influence) which will help to expla...

The level of activity of old people is measured by the special index called Active Aging Index. The main purpose of the article is to present this index as a tool to evaluate policy toward old people. Author focused on t...

White dwarf stars are the most common end point of stellar evolution. The ultramassive white dwarfs are of special interest as they are related to type Ia supernovae explosions, merger events, and fast radio bursts. Ultr...

Background Early screening of cognitive function is critical to dementia treatment and care. However, traditional tests require face-to-face administration and are often limited by implementation costs and biases.Aims Th...

We study the dynamics of an asymmetric intruder in a glass-former model. At equilibrium, the intruder diffuses with average zero velocity. After an abrupt quench to T deeply under the mode-coupling temperature, a net ave...

Abstract Background Population ageing presents increasing challenges for health systems. Identifying complex needs and planning individualized care through Comprehensive Geriatric Assessment (CGA), promoting intergenerat...

Os músculos Biceps femoris, Longissimus e Triceps brachii submetidos aos efeitos do tempo de maturação e da injeção com cloreto de cálcio de cordeiros Morada Nova foram estudados quanto às características de cor,...

Christos Kleisiaris,1 Theodora Arida,2 Maria Klesiora,1 Konstantinos Tsaras,1 Maria Malliarou,1 Ioanna V Papathanasiou,1 Theodosios Paralikas,1 Nikolaos Bakalis,3 Mahmoud Ogla Al-Hussami,4 Wafa Hamad Almegewly,5 Savvato ...

Background Tranexamic acid (TXA) is widely used for pigmentary disorders, but its anti-ageing potential remains unclear. This study aimed to evaluate whether topical 3% TXA improves early periorbital wrinkles in women wi...

Abstract Background Circadian rhythms are endogenous, transcription-translation feedback loops that align cellular activities with the 24-h light–dark cycle. Stem-cell populations across tissues exhibit circadian oscil...

In the last years, it has been discovered and intensely studied the non‐traditional intrinsic luminescence of polyamidoamine (PAMAM) dendrimers. Nevertheless, their aging process in aqueous suspension is scarcely studi...

Abstract Background Heart failure with preserved ejection fraction (HFpEF) disproportionately affects elderly women and is closely associated with central obesity and metabolic dysfunction. Although sodium-glucose co-tra...

BackgroundThe growing global population of older adults presents significant challenges for health and social care systems, requiring effective quality improvement (QI) interventions to enhance care delivery and outcomes...

Cardiorespiratory fitness (CRF) and skeletal muscle mass (SMM) are both key parameters of intrinsic capacity. To date, the impact of adherence to physical activity guidelines by older adults on these facets is poorly und...

To examine the effect of the NAD+ precursor, nicotinic acid (NA), for improving skeletal muscle status in sedentary older people.