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Optimising Perioperative Care in Craniotomy Patients : A Narrative Review of Opioid-free Anaesthesia Approaches

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Optimising Perioperative Care in Craniotomy Patients : A Narrative Review of Opioid-free Anaesthesia Approaches

Payodhi Modi et al · JCDR Research and Publications Private Limited · 2026 · ISSN 2249-782X

Opioid-free Anaesthesia (OFA) for craniotomy is a method employed increasingly for intraoperative and postoperative pain management with reduced opioid side-effects. Standard opioid regimens, although best for analgesia,...

LCC LCC:MedicineIdioma eng

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Efficacy of Intravenous Paracetamol Infusion versus Intravenous Pentazocine for Labour Analgesia: A Prospective Observational Study

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Efficacy of Intravenous Paracetamol Infusion versus Intravenous Pentazocine for Labour Analgesia: A Prospective Observational Study

S Anushree et al · JCDR Research and Publications Private Limited · 2026 · ISSN 2249-782X

Introduction: Labour pain is recognised as one of the most intense pain experiences. While neuraxial analgesia remains the gold standard, its limited accessibility in resource-constrained settings necessitates the use of...

LCC LCC:MedicineIdioma eng

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Pain Experience and Patient‐Reported Barriers to Analgesic Use in Emergency Care in Ghana: A Cross‐Sectional Study

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Pain Experience and Patient‐Reported Barriers to Analgesic Use in Emergency Care in Ghana: A Cross‐Sectional Study

Stephen Mensah Arhin et al · Wiley · 2026 · ISSN 2398-8835

ABSTRACT Background and Aims Effective pain management remains a critical component of emergency care. However, patient‐related beliefs and misconceptions about pain medication can pose significant barriers to adequate...

LCC LCC:MedicineIdioma eng

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Suzetrigine in the Management of Pain Review of the First-in-class Na V1.8 Selective Inhibitor

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Suzetrigine in the Management of Pain Review of the First-in-class Na V1.8 Selective Inhibitor

Maciej Przybył et al · Kazimierz Wielki University · 2026 · ISSN 2391-8306

Introduction. The 2025 FDA approval of suzetrigine (Journavx) ended a 25-year stagnation in analgesic development. This introduced a paradigm shift in pain management. As a first-in-class, highly selective NaV1.8 sodium...

LCC TENDOkVkdWNhdGlvbg~~; TENDOlNwb3J0cw~~; LCC:MedicineIdioma eng

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Balancing analgesia and immunity: revisiting the immune consequences of opioid therapy

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Balancing analgesia and immunity: revisiting the immune consequences of opioid therapy

Lucia Daiana Voiculescu et al · Open Exploration Publishing Inc · 2026 · ISSN 2768-6655

Opioids remain central to managing moderate to severe pain, yet they also produce significant and often under-recognized effects on the immune system. In this narrative review, we synthesize evidence from 1994 to 2025 ac...

LCC LCC:Immunologic diseases. AllergyIdioma eng

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Discrepancy Between Knowledge and Practice of Self‐Medication Among Adults in Dhaka, Bangladesh in 2023: A Cross‐Sectional Study

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Discrepancy Between Knowledge and Practice of Self‐Medication Among Adults in Dhaka, Bangladesh in 2023: A Cross‐Sectional Study

Salma Sultana et al · Wiley · 2026 · ISSN 2398-8835

ABSTRACT Background and Aims Self‐medication, while convenient for managing minor illnesses, poses significant public health risks when practiced without adequate knowledge or oversight. In Bangladesh, especially in ur...

LCC LCC:MedicineIdioma eng

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Influência da mobilidade materna na duração da fase ativa do trabalho de parto Influence of maternal mobility on duration of the active phase of labor

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Influência da mobilidade materna na duração da fase ativa do trabalho de parto Influence of maternal mobility on duration of the active phase of labor

Eliane Bio et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2006 · ISSN 0100-7203

OBJETIVOS: investigar a influência da mobilidade da parturiente durante a fase ativa do trabalho de parto. MÉTODOS: foi realizado ensaio clínico controlado prospectivo, com análise comparativa entre um grupo de trata...

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Intercostal block in a rabbit undergoing exploratory thoracotomy - case report

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Intercostal block in a rabbit undergoing exploratory thoracotomy - case report

A.F.F. Meznerovvicz et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2025 · ISSN 1678-4162

ABSTRACT Rabbits stand out in challenging anesthesia, due to their smaller size and different anatomy. Thoracic surgery is challenging due to the mandatory tracheal intubation to maintain positive ventilation and its hig...

LCC LCC:Animal cultureIdioma eng

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Mitochondrial dysfunction as a driver of chronic pain: New insights and therapeutic prospects

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Mitochondrial dysfunction as a driver of chronic pain: New insights and therapeutic prospects

Yi-Lin Fan et al · Elsevier · 2026 · ISSN 1096-1186

Chronic pain is a significant global health burden often resistant to conventional analgesics. Evidence implicates that mitochondrial dysfunction is not only a cellular consequence of injury, but also a fundamental drive...

LCC LCC:Therapeutics. PharmacologyIdioma eng

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Phα1β cardiovascular safety pharmacology using the telemetry system in rats

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Phα1β cardiovascular safety pharmacology using the telemetry system in rats

Celio José Castro Junior et al · Frontiers Media S.A · 2026 · ISSN 2674-0338

Phα1β, a peptide toxin purified from Phoneutria nigriventer spider venom, has a dual antinociceptive effect, inhibiting high-voltage-activated calcium channels and antagonising the TRPA1 receptor that differentiates it...

LCC LCC:Therapeutics. PharmacologyIdioma eng

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Synthesis and properties of novel alkoxy- and phenoxyalkyl ethers of secondary and tertiary ethynylpiperidin-4-ols possessing unusual analgesic, anti-bacterial, anti-spasmotic, and anti-allergic properties as well as low toxicity

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Valentina K. Yu et al · Springer · 2009 · ISSN 1319-6103

Abstract Methodology was developed to obtain a series of unusual alkoxy- and phenoxyalkyl ethers of secondary and tertiary ethynylpiperidin-4-ols representative examples of which were evaluated for analgesic, anti-bacter...

LCC TENDOkNoZW1pc3RyeQ~~Idioma eng

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The Association Between Patient Characteristics and Pain, Physical Function, and Quality of Life Among Patients with Hip Osteoarthritis: Explorative Study with Data from a Randomized Controlled Trial

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The Association Between Patient Characteristics and Pain, Physical Function, and Quality of Life Among Patients with Hip Osteoarthritis: Explorative Study with Data from a Randomized Controlled Trial

Jesper L Jensen et al · North American Sports Medicine Institute · 2026 · ISSN 2159-2896

# Background Hip Osteoarthritis (OA) is a degenerative joint disease associated with pain, reduced physical function, and impaired quality of life (QoL). Identifying patient characteristics associated with these outcomes...

LCC TENDOlNwb3J0cyBtZWRpY2luZQ~~Idioma eng

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