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The global rise of multidrug-resistant bacteria necessitates the development of new antimicrobials and faster diagnostic tools. Conventional antimicrobial susceptibility testing is slow, relying on culture-based methods ...

BackgroundCampylobacter is the most common cause of bacterial food infections worldwide. In Algeria, data regarding the epidemiology, antimicrobial resistance and virulence of Campylobacter remain limited. This study aim...

This study presents a novel regioselective synthesis of 3-electron-withdrawing-group-(EWG)-substituted 5-sulfonyl- and 5-sulfinylisoxazoles from 3-EWG-5-nitroisoxazoles via nucleophilic aromatic substitution with thiophe...

ABSTRACT Background and Aim Antimicrobial resistance is a global health crisis, with its impact magnified in conflict settings like Yemen, where a decimated health system and humanitarian emergency create ideal condition...

Abstract Antimicrobial peptides (AMPs) are a diverse class of short peptides with therapeutic potential as antimicrobial agents and immune regulators. Many anurans (frogs and toads) produce diverse sets of AMPs via speci...

ABSTRACT Background and Aims Infectious keratitis (IK) is classified as a critical ophthalmic emergency, with the potential to result in vision‐impairing complications. The treatment approach involves the use of pharma...

ABSTRACT Background and Aim Antimicrobial resistance (AMR) has been a growing crisis of economic, clinical, and public health concern for years. Different mechanisms of why and how AMR develops have been suggested and st...

Abstract In the present study, yttrium oxide (Y₂O₃) nanoparticles were successfully synthesized using different precipitating agents, namely acetic acid, oxalic acid, sodium carbonate, and urea, through a controlled ...

Abstract A novel Schiff base (L) was synthesized via the condensation of folic acid with salicylaldehyde, and its copper (II) complex (Cu–L complex) was subsequently prepared, exhibiting notable biological activity. Co...

Abstract The growing threat of antibiotic-resistant bacteria calls for the urgent development of novel antimicrobial agents. Binary chalcogenide nanoparticles, particularly Ag2Se nanoparticles, have emerged as promising ...

Brucellosis, a zoonotic disease, triggers severe inflammation and reproductive complications in both humans and animals. The standard treatment protocol relies on prolonged antibiotic courses, often combining streptomyci...

Abstract Background Antimicrobial resistance (AMR) constitutes a formidable global health threat, spanning bacterial, viral, and fungal pathogens. Within this broader context, antibiotic resistance (ABR)—specifically t...

The rising concern of antimicrobial resistance, coupled with the continually challenging management of complicated diseases such as cancer, has provided momentum toward precision molecular medicine. This review provides ...

Abstract Silver nanoparticles (AgNPs) have gained relevance in restorative dentistry due to their antimicrobial and remineralizing properties. However, the role of AgNPs functionalized with different polyphenols in denti...

Introduction: Ventilator Associated Pneumonia (VAP) is a common Healthcare Associated Infection (HAI) in mechanically ventilated patients, leading to increased morbidity, mortality, Intensive Care Unit (ICU) stays, and h...

Quinolines are well-established scaffolds in drug discovery and form the core of many FDA-approved medicines. Among their reduced analogues, hexahydroquinolines (HHQs) have gained increasing attention due to their struct...

Ziye Liu,1 Meiyu Deng,2 Bu Wang,2 Jianhua Liu,2 Wei Zhang,3,* Jianqing Zhao2,* 1Department of Respiratory Medicine, The First School of Clinical Medicine, Hebei North University, Zhangjiakou, Hebei, Peopl...

Cancer therapy and food preservation both face significant challenges related to stability, targeted delivery, safety, and efficiency of active compounds. Biopolymer-based nanoparticles, particularly those derived from c...

Acne vulgaris is a common inflammatory skin condition that affects up to 85% of adolescents and is primarily driven by Cutibacterium acnes (anaerobic bacteria, formerly Propionibacterium acnes). With the rise of antibiot...

Millions of microorganisms—including bacteria, viruses, fungi, archaea, and protists—reside on and within the human body, collectively forming the human microbiota. This complex and dynamic community plays a crucial ...

Abstract This study reports the sustainable green synthesis of magnesium oxide nanoparticles (MgONPs) using peel extracts from two avocado cultivars, Persea americana Mill. Hass and Fuerte, and demonstrates the strong in...

Abstract Curcumin, a natural polyphenol with multifaceted anticancer properties, faces significant clinical translation challenges due to poor solubility, rapid metabolism, and low bioavailability. Hydrogels, as biocompa...

ABSTRACT Background and Aims Septic abortion remains a major cause of maternal morbidity and mortality in low‐ and middle‐income countries. This study aimed to determine the prevalence, antibiotic susceptibility prof...