NODOVOX | Discovery

Bioavailability of butorphanol after intranasal administration to horses

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Bioavailability of butorphanol after intranasal administration to horses

Ferreira, V. et al · Trakia University · 2020 · ISSN 1311-1477

The aim of the present study was to describe butorphanol pharmacokinetics and bioavailability following intranasal administration to horses. Six adult horses received 0.05 mg/kg butorphanol, in a randomised crossover des...

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Bioavailability of dietary antioxidants in Acanthopanax sieboldianus Makino leaves

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Bioavailability of dietary antioxidants in Acanthopanax sieboldianus Makino leaves

Tomoko Ueno et al · Society for Science and Technology · 2013 · ISSN 2186-4942

We have investigated the intestinal absorption and metabolism of the polyphenols contained in Acanthopanax sieboldianus Makino (Ukogi in Japanese) in rat plasma using a liquid chromatography/mass spectrometry (LC/MS). Uk...

LCC LCC:Technology (General)Idioma eng

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Effects of sourdough- or regular-bread fermentation, and phytate reduction on iron bioavailability, absorption, and iron status in humans: a systematic review of intervention studies

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Effects of sourdough- or regular-bread fermentation, and phytate reduction on iron bioavailability, absorption, and iron status in humans: a systematic review of intervention studies

Anastasios Nikolaou et al · Frontiers Media S.A · 2026 · ISSN 2296-861X

This systematic review, conducted under the COST Action CA20218 “Promoting Innovation of fermented foods” (PIMENTO), aimed to evaluate whether sourdough- and regular-bread fermentation improve iron bioavailability, a...

LCC LCC:Nutrition. Foods and food supplyIdioma eng

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In vitro bioavailability and gender-specific fermentation of an Opuntia ficus-indica extract combining cladodes and fruit skins with synergistic prebiotic and metabolic actions

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In vitro bioavailability and gender-specific fermentation of an Opuntia ficus-indica extract combining cladodes and fruit skins with synergistic prebiotic and metabolic actions

Lorenzo Marino Cerrato et al · Elsevier · 2026 · ISSN 1756-4646

Opuntia ficus-indica (OFI) is traditionally recognized for its antioxidant and health-promoting properties, yet evidence on the bioaccessibility, bioavailability, microbiota-related effects and mechanism of action of sta...

LCC LCC:Nutrition. Foods and food supplyIdioma eng

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Determinação da biodisponibilidade do fósforo de diferentes fontes pela técnica de diluição isotópica, em suínos em crescimento Bioavailability determination of phosphorus from different sources, using the isotopic dilution technique, for growing swine

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Alexandre de Oliveira Teixeira et al · Sociedade Brasileira de Zootecnia · 2004 · ISSN 1516-3598

Foram utilizados 28 leitões machos, com peso médio de 28,95 kg, para determinação das perdas endógenas fecais, da absorção verdadeira e da biodisponibilidade do fósforo de diferentes fontes. Utilizou-se o delinea...

LCC LCC:Animal cultureIdioma eng

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Effect of phytase supplementation of a plant-based diet on phosphorus and nitrogen bioavailability in sea bream Sparus aurata

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Effect of phytase supplementation of a plant-based diet on phosphorus and nitrogen bioavailability in sea bream Sparus aurata

Morales, Gabriel Alejandro et al · Wiley · 2014 · ISSN 1353-5773

To assess to what extent addition of phytase to a plant-based diet results in spatio-temporal changes of phytate, available P, soluble protein, total amino acids and the activity of the main digestive proteases in gilthe...

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Exigência de fósforo disponível e efeito da granulometria na biodisponibilidade de fósforo da farinha de carne e ossos para pintos de corte Available phosphorus requirement and effect of particle size on phosphorus bioavailability from meat and bone meal for broiler chicks

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Irineu Brugalli et al · Sociedade Brasileira de Zootecnia · 1999 · ISSN 1516-3598

O objetivo deste trabalho foi determinar a exigência nutricional de P disponível e o efeito da granulometria na biodisponibilidade de P da farinha de carne e ossos (FCO) para pintos de corte. Duzentos e cinqüenta e 45...

LCC LCC:Animal cultureIdioma eng

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Bioequivalence evaluation of two brands of ketoprofen 50 mg capsules (Flogofin® & Profenid®) in healthy latin american volunteers

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Bioequivalence evaluation of two brands of ketoprofen 50 mg capsules (Flogofin® & Profenid®) in healthy latin american volunteers

Baldo, M. N. et al · OMICS · 2015 · ISSN 0975-0851

The study was performed to compare the bioavailability of two ketoprofen capsule (50 mg) formulations: Flogofin®, as test formulation, and Profenid®, as reference formulation. The study was conducted open with randomiz...

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Black cumin (Nigella sativa) oleosome as a natural delivery system for curcumin: characterization, preparation, and in vitro digestive behavior

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Black cumin (Nigella sativa) oleosome as a natural delivery system for curcumin: characterization, preparation, and in vitro digestive behavior

Negin Hosseini et al · Frontiers Media S.A · 2026 · ISSN 2296-861X

Oleosomes, also known as oil bodies (OBs), are naturally occurring colloidal particles present in edible plant seeds and nuts and possess unique functional properties. In this study, oleosomes derived from black cumin (B...

LCC LCC:Nutrition. Foods and food supplyIdioma eng

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Contaminação por mercúrio em ecossistemas aquáticos: uma análise das áreas críticas Mercury contamination in aquatic ecosystems: an analysis of the critical areas

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Contaminação por mercúrio em ecossistemas aquáticos: uma análise das áreas críticas Mercury contamination in aquatic ecosystems: an analysis of the critical areas

Luiz Drude de Lacerda et al · Universidade de São Paulo · 2008 · ISSN 0103-4014

O processo de contaminação por mercúrio em ecossistemas aquáticos é discutido, levando-se em consideração as características biogeoquímicas atuantes nesses sistemas que resultam em uma maior mobilização e biod...

LCC TENDOlNvY2lhbCBzY2llbmNlcyAoR2VuZXJhbCk~Idioma eng

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Formulation and evaluation of self-emulsifying drug delivery system (SEDDS) for nevirapine

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Formulation and evaluation of self-emulsifying drug delivery system (SEDDS) for nevirapine

Sana Shahzad et al · AMMANIF · 2025 · ISSN 2521-0521

This study focuses on the development and optimization of a self-emulsifying drug delivery system (SEDDS) for Nevirapine, a BCS Class II non-nucleoside reverse transcriptase inhibitor (NNRTI) used in HIV therapy. Our obj...

LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng

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Advances of curcumin-loaded hydrogels for multimodal cancer therapeutics

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Advances of curcumin-loaded hydrogels for multimodal cancer therapeutics

Kexin Tang et al · Springer · 2026 · ISSN 2730-6011

Abstract Curcumin, a natural polyphenol with multifaceted anticancer properties, faces significant clinical translation challenges due to poor solubility, rapid metabolism, and low bioavailability. Hydrogels, as biocompa...

LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng

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An assessment of curcumin, curcumin spanlastics nanoparticles, and curcumin nanocrystals as possible drug delivery systems with antimicrobial, antioxidant, and antitumor activities

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An assessment of curcumin, curcumin spanlastics nanoparticles, and curcumin nanocrystals as possible drug delivery systems with antimicrobial, antioxidant, and antitumor activities

Jawza A. Almutairi et al · BMC · 2026 · ISSN 1472-6750

Abstract Background Curcumin is one such polyphenol that has low bioavailability as well as solubility. Therefore, the present study has analyzed, investigated, and estimated the antimicrobial, antioxidant, and anticance...

LCC TENDOkJpb3RlY2hub2xvZ3k~Idioma eng

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Anti-psoriatic and Anti-inflammatory Potentials of Phytochemicals from Curcuma longa against Interleukin-17A and Inducible Nitric Oxide Synthase: An In Silico Study

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Anti-psoriatic and Anti-inflammatory Potentials of Phytochemicals from Curcuma longa against Interleukin-17A and Inducible Nitric Oxide Synthase: An In Silico Study

Misbaudeen Abdul-Hammed et al · Universitas Gadjah Mada · 2024 · ISSN 1410-5918

LCC LCC:MedicineIdioma eng

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Anticancer activity of an apigenin-functionalized silica-coated silver oxide nanocomposite against human gastric adenocarcinoma cells (AGS): in vitro and in silico analysis

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Anticancer activity of an apigenin-functionalized silica-coated silver oxide nanocomposite against human gastric adenocarcinoma cells (AGS): in vitro and in silico analysis

Seyed Milad Mousavi Eshkelani et al · BMC · 2026 · ISSN 1472-6750

Abstract Silver nanoparticles show promise anticancer agents, yet their clinical translation is hindered by poor bioavailability and nonspecific toxicity. In this study, we developed an apigenin-functionalized silica-coa...

LCC TENDOkJpb3RlY2hub2xvZ3k~Idioma eng

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Bioremediation approaches in a laboratory activity for the Industrial Biotechnology and Applied Microbiology (IBAM) course

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Bioremediation approaches in a laboratory activity for the Industrial Biotechnology and Applied Microbiology (IBAM) course

Raiger Iustman, Laura Judith et al · American Society for Microbiology · 2013 · ISSN 1935-7877

Industrial Biotechnology and Applied Microbiology is an optional 128h-course for Chemistry and Biology students at the Faculty of Sciences, University of Buenos Aires, Argentina. This course is usually attended by 25 stu...

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Carrot Anthocyanin Diversity, Genetics, and Genomics

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Carrot Anthocyanin Diversity, Genetics, and Genomics

Cavagnaro, Pablo Federico et al · Springer · 2019 · ISSN 2199-4781

Purple carrots (Daucus carota ssp. sativus var. atrorubens Alef.) accumulate anthocyanins in their roots, petioles and other plant parts. These flavonoid pigments represent an excellent dietary source of antioxidant and ...

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DNA framework-based nanomedicine platform: a triple-function strategy for treating periodontitis via antibacterial, anti-inflammatory, and osteogenesis-promoting activities

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DNA framework-based nanomedicine platform: a triple-function strategy for treating periodontitis via antibacterial, anti-inflammatory, and osteogenesis-promoting activities

Geru Zhang et al · Nature Publishing Group · 2026 · ISSN 2049-3169

Abstract Periodontitis is the most prevalent chronic inflammatory condition affecting oral health and is associated with long treatment duration. It is triggered by microbial plaque, which leads to localized and diffuse ...

LCC TENDOkRlbnRpc3RyeQ~~Idioma eng

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Efficacy and Safety of Tetracyclines in Bone and Joint Infections: A Literature Review

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Efficacy and Safety of Tetracyclines in Bone and Joint Infections: A Literature Review

Paul Laffont-Lozes et al · Adis, Springer Healthcare · 2026 · ISSN 2193-8229

Abstract Introduction Bone and joint infections (BJIs) are complex and difficult to eradicate, and have high relapse rates and limited oral treatment options. Tetracyclines combine favorable bone penetration, oral bioava...

LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng

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Efficacy of Omeprazole Powder Paste or Enteric‐Coated Formulation in Healing of Gastric Ulcers in Horses

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Efficacy of Omeprazole Powder Paste or Enteric‐Coated Formulation in Healing of Gastric Ulcers in Horses

K. Birkmann et al · Oxford University Press · 2014 · ISSN 0891-6640

Background GastroGard, an omeprazole powder paste formulation, is considered the standard treatment for gastric ulcers in horses and is highly effective. Gastrozol, an enteric‐coated omeprazole formulation for horses, ...

LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng

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Enhancing Albendazole Delivery Using Mesoporous Santa Barbara Amorphous‐15: A Box‐Behnken Design Study

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Enhancing Albendazole Delivery Using Mesoporous Santa Barbara Amorphous‐15: A Box‐Behnken Design Study

Gallo, Loreana Carolina et al · Wiley VCH Verlag · 2024 · ISSN 1438-1656

Over 70% of pharmaceutical compounds face the challenge of poor water solubility, which impacts on their bioavailability. This study focuses on the use of Santa Barbara Amorphous-15 (SBA-15) mesoporous silica material as...

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Fabrication and characterization of colon targeted ibuprofen nanoparticles

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Fabrication and characterization of colon targeted ibuprofen nanoparticles

Ayesha Riaz et al · AMMANIF · 2024 · ISSN 2521-0521

Aim: The objective of our study was to formulate a nanoparticulate drug delivery system that provides controlled delivery of ibuprofen directly targeting colon leading to optimized dosage, reduced side effects ultimately...

LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng

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Fat substitutes based on bovine blood plasma and flaxseed oil as functional ingredients

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Fat substitutes based on bovine blood plasma and flaxseed oil as functional ingredients

Fernández, Carina Lorena et al · Elsevier · 2021 · ISSN 1878-450X

Technological and structural properties of edible flaxseed oil oleogels with dehydrated full bovine blood plasma as structuring agent were evaluated, envisioned oleogels as potential sustainable saturated fat replacers i...

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Formulation and evaluation of transdermal patch of lidocaine HCl for insect bite

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Formulation and evaluation of transdermal patch of lidocaine HCl for insect bite

Arjmand Mushtaq et al · AMMANIF · 2023 · ISSN 2521-0521

Objective: Lidocaine needs to be administered frequently as it has poor oral bioavailability and it lacks prolong duration of action thus the study was aimed at to devise, develop, and analyze a matrix system transdermal...

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