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ABSTRACT Background and Aims The present review aims to ascertain whether reproductive disorders are associated with specific physical, mental, personality, and social traits. This information may be used to support or r...

A 10-year-old patient was admitted to the pediatric sub-intensive care unit due to massive rectal bleeding and severe acute anemia. His medical background included Asperger syndrome and a history of chronic constipation ...

ABSTRACT Introduction Menstrual disorders and abnormal uterine bleeding are among the most frequent reasons for gynecological consultation among women, especially young women. Method Observational multicenter study with ...

Background: Hemophilia is a genetic bleeding disorder resulting from a deficiency of specific coagulation factors. The most common forms, hemophilia A and B, are X-linked and mainly affect males, with females usually bei...

Background: Anaemia remains a major public health concern in pregnancy and is associated with adverse maternal and perinatal outcomes. Low-dose aspirin (LDA) is widely prescribed to reduce the risk of preeclampsia (PE),...

Hemophilia B is an X-linked recessive bleeding disorder caused by deficiency or dysfunction of factor IX. It typically presents with spontaneous or trauma-induced bleeding, hemarthrosis, and soft tissue hematomas. We rep...

ABSTRACT Background Anticoagulation therapy is central to the prevention of thromboembolic disorders but is limited by bleeding complications associated with traditional agents such as warfarin and direct oral anticoagul...

Haematohidrosis is an exceptionally rare and poorly understood clinical phenomenon characterized by the spontaneous excretion of blood through intact skin or natural orifices, with episodes often reported in association ...

IntroductionThe MIRACLE Task Force is a multidisciplinary, multi-institutional work group comprising immunology, genetics, obstetrics/gynecology, and maternal fetal medicine providers dedicated to understanding reproduct...

Prekallikrein (PK) and selective IgA deficiencies are rare, and their coexistence in a cardiac transplant patient presents unique challenges. These disorders affect anticoagulation monitoring and transfusion safety, nece...

Gestational trophoblastic disease (GTD) includes both neoplastic and nonneoplastic disorders arising from placental trophoblastic tissue. Among tumor-like conditions, exaggerated placental site reaction (EPSR) is a rare ...

BackgroundMore than one-fourth of the world’s burden of ARPC1B deficiency (ARPC1BD), a rare immune-actinopathy, is reported from Nepal, a resource-constrained Himalayan country with a single trained immunologist. The d...

Objectives: Skin disorders are a common health condition that affects people of all ages, from newborns to the elderly, and inflicts injury in a variety of ways. If the cracks in the heels are severe, they can be uncomfo...

BackgroundChromosome 22q11.2 deletion syndrome is the most common microdeletion chromosomal anomaly. Frequent infections have been described as a major feature of immunodeficiency noted in 22qDS. Immune dysregulation is ...

Abstract Background Limited awareness of placental mesenchymal dysplasia (PMD) and the diagnostic challenges in differentiating it from partial hydatidiform moles on imaging often lead to inappropriate management. This s...

Subcapsular hepatic hematoma with hepatic rupture in the postpartum period is a rare but potentially fatal condition, most commonly associated with hypertensive disorders of pregnancy and HELLP syndrome. In women without...

Abstract Background Video capsule endoscopy (VCE) is a noninvasive imaging modality that can identify mucosal lesions not detected with traditional endoscopy or abdominal sonography. In people, VCE is used in diagnostic ...

Abstract Background Ankylosing spondylitis (AS) is a chronic inflammatory disorder marked by spinal ossification that leads to progressive thoracolumbar kyphosis (TLK). We previously introduced vertebral body compression...