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Extensive burns are associated with numerous severe complications. While paralytic ileus is relatively common, the co-occurrence of acute pancreatitis (AP) is rare, clinically insidious, and highly fatal. Diagnosis is pa...

Introduction: Low-voltage electrical injuries are generally considered low risk but can cause significant thermal injury when current is concentrated through conductive materials. Circumferential neck burns from mobile p...

Introduction: Optimal transfusion thresholds in burn patients remain a topic of debate. While liberal strategies aim to improve oxygen delivery, restrictive protocols may minimize transfusion-related risks. Evidence in g...

Bilateral isolated cerebral peduncle infarction is a rare stroke, previously reported only in adults. This report describes a paediatric burns patient with preceding cardiac arrest who developed subtle neurology. Imaging...

Background: Pseudomonas aeruginosa is an opportunistic bacterium that causes nosocomial infections in hospitals. It can develop high-level multidrug resistance (MDR). The MexA gene is a constitutive chromosomal gene in t...

Abstract Introduction Across the globe, traditional medicine, particularly herbal remedies, is a cornerstone of healthcare. While the medicinal uses of ferns are widely recognized globally, their therapeutic potential in...

Danyang Yang,1 Xin Liu,1 Wenwen Jing,1 Xu Feng,1 Canying Lai,1 Chenyue Liu,2 Zhigang Xu,1,3 Yangang Zhang,1 Jiayi Han,1 Songmei Geng,1 Ruilian Li,1 Dan Li,4 Boyi Cheng,1 Yufei Wu,1 Zhuokun Liu,1 Jialin Lian,1 Zhenghui Wa...

We present a case report of a 10-year-old girl who sustained significant facial burns after microwaving a frozen stress ball; just one example of a “trend” which quickly gained popularity without disclaiming the harm...

Burn injuries represent a major public health concern worldwide, with a disproportionately high burden observed in developing nations. The healing of second-degree burns engages a series of intricate cellular and molecul...

IntroductionCGD is an inborn error of immunity that results in severe, recurrent bacterial and fungal infections, immune dysregulation, and chronic inflammation. Profiling the cytokine signature in CGD patients may infor...

Abstract Background Proteins and RNA circulate in plasma and can offer insights into human physiology. Yet, despite their clinical importance, direct comparisons between these analytes remain unexplored. Methods: Here, w...

Food festivals are a sustainable alternative for destinations to promote their culture and other attractions. This study aimed to achieve the following objectives at a gastronomic festival: (i) Identify demand drivers; (...

Abstract This multicenter, first-in-human Phase 1 study (NCT04956640) evaluated olomorasib (LY3537982), a next-generation KRAS G12C inhibitor designed to enhance target occupancy at low absolute exposures. In total, data...

IntroductionChronic Granulomatous Disease (CGD) is an inborn error of immunity that can be treated by allogeneic hematopoietic stem cell transplantation (allo-HSCT) or experimental gene therapy. For viral vector-based in...

IntroductionAn emerging body of evidence suggests that plasma neuropeptide Y (NPY) concentration is positively associated with performance under conditions of psychological stress. However, whether NPY concentrations in ...

Abstract This commentary shares reflections and learning about the factors that supported the meaningful involvement of a service user being funded to undertake a service evaluation in a health and social care trust in N...