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Despite the link between conflict and human trafficking having been globally recognised, academic inquiry investigating how the two interact continues to be limited. Given the recency of the full-scale invasion of Ukrain...

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Multinational and state efforts designed to curtail illegal migration in Nigeria and indeed in Edo state have only succeeded in yielding modest outcome. Illegal migration has continued to grow in the face of threats from...

Objectives: This study examines the convergence of smuggling and trafficking in persons along the Central Mediterranean Route (CMR) to Europe. We explore where and how these phenomena blur, impacting states’ obligation...

Whooping cough is a reemerging disease caused by two closely related pathogens, Bordetella pertussis and Bordetella parapertussis. The incidence of B. parapertussis in whooping cough cases has been increasing since the i...

In recent years, tackling effectively human trafficking has become priority for the EU legislator. The Directive on this subject was adopted on the 5th o April 2011. It is designed to provide the powerful measures to pre...

This Campbell systematic review searched for studies which examined the effectiveness of anti‐trafficking measures (policies and interventions) to prevent or suppress cross‐border trafficking for the purpose of sexua...

Type 2 diabetes mellitus (T2D) features chronic low-grade inflammation in white adipose tissue (WAT), where adipocytes and innate immune cells engage in immunometabolic crosstalk. Mitochondrial damage-associated molecula...

While studying familial celiac disease, we identified four individuals with a rare heterozygous loss-of-function variant in the highly conserved, early-evolved ABCF1 gene. In addition, the 246 individuals heterozygous fo...

This study aims to examine migration dynamics and the socioeconomic factors influencing migration in Kyrgyzstan, Kazakhstan, and Uzbekistan. In Kyrgyzstan, internal migration from rural areas to cities is prevalent, whil...

The article examines the effectiveness of the Maritime Security Architecture (MSA) in the Western Indian Ocean Region (WIOR), focusing on how well it addresses traditional, non-traditional, and emerging maritime threats....

Abstract Background Hypoxia is a critical factor contributing to neuronal injury, primarily through dysregulation of hypoxia-inducible factor-1 alpha (HIF-1α). This study aimed to investigate the neuroprotective effects...

Abstract Background and hypothesis CD5L is a glycoprotein induced during inflammation and makes a life-saving contribution in infection and sepsis. Here, we explored the immunomodulatory effect of CD5L in rheumatoid arth...

Abstract Tunneling nanotubes (TNTs) play a crucial role in intercellular communication, enabling transfer of molecular cargoes over long distances between connected cells. Previous studies have demonstrated efficient, di...

Background and AimMost infections are innocuous in most individuals, and most infectious diseases are confined to specific organs. Inborn errors of tissue-intrinsic, non-leukocytic immunity underlie some organ-specific i...

Human induced pluripotent stem cells (iPSCs) are transforming adoptive cell therapy by combining unlimited self-renewal, broad differentiation potential, and high amenability to genome engineering. These attributes make ...

Chlamydia psittaci is an obligate intracellular pathogen that poses a significant threat to both human and animal health. The current therapeutic strategies are limited by the emergence of potential drug resistance, unde...

Inborn errors of immunity (IEI) can manifest with neurological disorders, indicating genetic overlap between immune and nervous system diseases. However, neurological disorder genes are rarely screened systematically for...

Galactosemia involves different forms of inborn errors of metabolism affecting galactose processing. Different from type 1 and type 2, respectively, related to GALT and GALK1 defects, type 3 galactosemia is due to bialle...

Oligodendrocytes (OLG) are the cells resident in the CNS responsible for myelination. OLG undergo a succession of morphological and molecular changes along several maturational stages. Galectin-3 (Gal-3) is a 25- to 35-K...