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Abstract Accurate prediction of invasive mechanical ventilation (IMV) requirement in patients with community-acquired pneumonia (CAP) is a key clinical challenge. Conventional static risk stratification scores have limit...

Abstract Enhanced comfort and effective sedation are essential for mechanically ventilated patients, particularly in the ICU. This study evaluates the safety and effectiveness of remimazolam, a novel ultra-short-acting b...

ObjectiveThe study aimed to assess the effects of resting energy expenditure (REE) on critically ill individuals requiring mechanical ventilation with different degrees of sedation.DesignA prospective self-controlled stu...

Background and aimCardiac surgery requiring cardiopulmonary bypass (CPB) is associated with a high rate of postoperative pulmonary complications (PPCs). Mechanical power (MP) represents energy per breath multiplied by re...

INTRODUCTION: Aim is to investigate changes in intracranial pressure (ICP) during the weaning process by comparing continuous positive airway pressure (CPAP) and T-piece spontaneous breathing trials using serial optic ne...

IntroductionProlonged immobilization in the intensive care unit (ICU) leads to ICU-acquired weakness (ICU-AW), which delays ventilator liberation and worsens outcomes. Although early mobilization is beneficial, and the P...

Chunyan Lin, Ting Huang, Huangyi Wu, Yanzhu Lin, Chunling Guo, Liduan Li NICU, the Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, 362000, People’s Republic of ChinaCorrespondence: Liduan Li,...

ABSTRACT Aims This study aimed to assess the nutritional status of COVID‐19 patients within the first 24 h of Intensive Care Unit (ICU) admission and to determine its association with the risk of mechanical ventilati...

Abstract Background Volatile anesthetics are widely used for sedation in intensive care. Being potent greenhouse gases, their efficient utilization is imperative. We investigated whether the efficiency of anesthetic refl...

Abstract Background Prone positioning is recommended for patients with acute respiratory distress syndrome not only to improve oxygenation, but also to reduce lung stress, and lower mortality. The association between imp...

Indoor air quality is a crucial factor that directly impacts worker safety and health (K3), where exposure to hazardous pollutants such as formaldehyde can trigger irritation, respiratory disorders, and long-term health ...

ABSTRACT High-frequency oscillatory ventilation (HFO) is a mechanical ventilation technique used in veterinary medicine to treat various respiratory diseases, particularly in small animal patients, but its potential appl...

IntroductionKabuki syndrome (KS) is a rare, complex, multisystem, neurodevelopmental congenital disorder with characteristic phenotypic anomalies and pathogenic genetic variants of the KMT2D or KDM6A genes. KS is highly ...

BackgroundBronchopulmonary dysplasia (BPD) is a common and serious complication in very preterm infants, with potential long-term adverse effects. This study aimed to analyze the perinatal and postnatal risk factors for ...

AIM: Acute renal failure (ARF) is an important clinical problem in the neonatal period and usually related with a primary disease. Unless diagnosed early and treated properly, it may cause significant mortality and mor...

ObjectiveTo analyze the rates of drug resistance of carbapenem-resistant Klebsiella pneumoniae (CRKP) and extended-spectrum β-lactamase-producing Escherichia coli (ESBL-E.coli) in bronchoalveolar lavage fluid (BALF) of ...

Abstract Background While antenatal corticosteroids (ACSs) are standard for early preterm birth, their benefit‒risk profile for the late preterm period is controversial, and the effect of the ACS-to-delivery interval o...

Abstract Background Mortality prediction in critically ill patients is commonly performed with scoring systems such as SOFA and APACHE II. The arterial-to-end-tidal carbon dioxide gradient [P(a–et)CO₂], which can be ...

Abstract Background and aim Severe pneumonia is associated with high mortality rates. Nutritional and inflammatory status significantly impacts outcomes. While albumin-based indices have been demonstrated to predict outc...

Abstract Heart failure (HF) and chronic obstructive pulmonary disease (COPD) frequently co-occur, complicating treatment. Concerns about respiratory complications often lead to underuse of β-blockers in this population....

Objective: In contrast to penetrating trauma, blunt pancreatic trauma poses numerous challenges for treating surgeons, mainly due to the different clinical manifestations. Materials and methods: This is a retrospective o...

BackgroundItchy E3 ubiquitin ligase deficiency (ITCH deficiency) is a rare monogenic immune dysregulation syndrome characterized by early-onset multisystem autoimmunity and significant morbidity and mortality. Only one p...

Abstract Introduction Respiratory syncytial virus (RSV) is a major cause of morbidity and mortality among older adults. Limited information is available in Israel regarding RSV outcomes, particularly compared to influenz...

Introduction: The neonatal period is one of the most critical phases in an individual’s life. During this time, newborns undergo significant physiological changes as they adapt from the intrauterine to the extrauterine...