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79 resultados encontrados.

Tipos de recurso: Libro electrónico Artículo Revista Tesis Capítulo
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Methods for specifying the target difference in a randomised controlled trial: the Difference ELicitation in TriAls (DELTA) systematic review.
Artículo
Acceso abierto Artículo DOAJ
Jenni Hislop et al · Public Library of Science (PLoS) · 2014 · ISSN 1549-1277
BackgroundRandomised controlled trials (RCTs) are widely accepted as the preferred study design for evaluating healthcare interventions. When the sample size is determined, a (target) difference is typically specified th...
LCC LCC:MedicineIdioma eng
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Open Access
Research synthesis and meta‐analysis of Monte Carlo studies: the best of two worlds
Artículo
Acceso abierto Artículo DOAJ
Brandon LeBeau · SAGE Publishing · 2017 · ISSN 1891-1803
ABSTRACT Research syntheses and meta‐analyses have been widely used to combine primary applied research studies. To date, there has been little work applying these methods to combine Monte Carlo studies, however narrat...
LCC TENDOlNvY2lhbCBTY2llbmNlcw~~Idioma eng
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Open Access
A Narrative Review on Integrative Bioinformatics Approaches for microRNA Research in Familial Mediterranean Fever: Current Insights and Future Directions
Artículo
Acceso abierto Artículo DOAJ
Zeinab Skaineh et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background and Aims Familial Mediterranean Fever (FMF) is a monogenic autoinflammatory disease caused by mutations in the MEFV gene, resulting in recurrent inflammatory episodes and a risk of developing amyloido...
LCC LCC:MedicineIdioma eng
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Open Access
RECONTEXTUALIZING EFL READING INSTRUCTION THROUGH LOCAL WISDOM: A MIXED-METHODS STUDY OF PROBLEM-BASED LEARNING
Artículo
Acceso abierto Artículo DOAJ
Lanlan Muhria et al · LPPM Universitas Labuhanbatu · 2026 · ISSN 2303-355X
Purpose – This study investigates how recontextualizing EFL reading instruction through local-wisdom-based Problem-Based Learning (PBL) supports students’ reading comprehension and learning experiences. Methodology ...
LCC TENDOkVkdWNhdGlvbg~~Idioma eng
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Open Access
Addressing low-value care (LVC) in Asia: a narrative review of Choosing Wisely and other initiatives across Asia
Artículo
Material complementario disponible Artículo DOAJ
Jay Pan et al · BMJ Publishing Group · 2026 · ISSN 2399-6641
Background Low-value care (LVC) research originates predominantly from Western healthcare systems. This narrative review offers the first synthesis of LVC patterns, determinants and reduction initiatives across six diver...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.
Material complementario
Antiviral peptides as emerging therapeutic agents: a narrative review of engineering strategies, delivery innovations, and clinical perspectives
Artículo
Acceso abierto Artículo DOAJ
Maryia Bohdzel et al · Nicolaus Copernicus University in Toruń · 2026 · ISSN 2450-3118
Background. Viral infections remain a major global health threat despite advances in vaccines and antiviral drugs due to the rapid emergence of resistance and new viral pathogens. Antiviral peptides (AVPs) are promising ...
LCC TENDOlNwb3J0cw~~; TENDOlNwb3J0cyBtZWRpY2luZQ~~Idioma eng
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Open Access
Efficacy and safety of GLP-1 Receptor Agonists for BMI Reduction in Children and Adolescents with Obesity: A Narrative Review
Artículo
Material complementario disponible Artículo DOAJ
Justyna Pestka et al · Nicolaus Copernicus University in Toruń · 2026 · ISSN 2450-3118
Background. Obesity arises as a global health issue, increasingly affecting children and adolescents. Excess body weight is associated with multiple metabolic risks and poor quality of life. Lifestyle therapy remains the...
LCC TENDOlNwb3J0cw~~; TENDOlNwb3J0cyBtZWRpY2luZQ~~Idioma eng
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Material complementario
Is histamine intolerance a treatable subtype of fibromyalgia? evidence and clinical implications—narrative review
Artículo
Material complementario disponible Artículo DOAJ
João Protásio Netto et al · Frontiers Media S.A · 2026 · ISSN 2673-561X
BackgroundFibromyalgia affects 2%–8% of the global population with suboptimal treatment outcomes. Emerging evidence suggests histamine intolerance, mediated by diamine oxidase (DAO) deficiency, may contribute to fibrom...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Material complementario
Management of hip fracture in older adults with cognitive impairment: a narrative review
Artículo
Acceso institucional disponible Artículo DOAJ
Hao Rao et al · Frontiers Media S.A · 2026 · ISSN 2296-2565
BackgroundHip fractures in older adults are costly and often fatal. Cognitive impairment (CI) complicates pain assessment, raises delirium risk, and hinders early mobilization and rehabilitation. This review synthesizes ...
LCC LCC:Public aspects of medicineIdioma eng
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Institucional
Mapping Researcher Identity in Culturally Diverse Teams Investigating Health Inequalities in High-Income Countries: A Scoping Review Protocol
Artículo
Material complementario disponible Artículo DOAJ
Adanna Achinanya et al · SAGE Publishing · 2026 · ISSN 1609-4069
Background Researcher identity and positionality shape how studies of health inequalities are conceptualised, conducted, and interpreted, particularly within culturally diverse teams. Yet there is no consolidated map of ...
LCC TENDOlNvY2lhbCBzY2llbmNlcyAoR2VuZXJhbCk~Idioma eng
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Material complementario
Mapping fMRI research in disorders of consciousness: a bibliometric study
Artículo
Material complementario disponible Artículo DOAJ
Xi-Chen Wang et al · Frontiers Media S.A · 2026 · ISSN 1664-2295
ObjectiveTo systematically map the evolution, academic network structure, and emergent research fronts of functional magnetic resonance imaging (fMRI) applications in prolonged disorders of consciousness (pDoC) through b...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Material complementario
Progressive health states and transition probabilities in pediatric dental caries: a systematic review of current evidence and research gaps
Artículo
Acceso abierto Artículo DOAJ
Xenia Teplitzky et al · Frontiers Media S.A · 2026 · ISSN 2673-4842
IntroductionUnderstanding the progression of dental caries in children, characterized by transitions between distinct health states, may benefit the development of prevention and disease modeling frameworks. This systema...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Open Access
Sex Differences in Stress Fracture Incidence and Risk Factors in Athletes: A Narrative Review
Artículo
Acceso abierto Artículo DOAJ
Jakub Rudnicki et al · Nicolaus Copernicus University in Toruń · 2026 · ISSN 2450-3118
Background. Stress fractures are a prevalent overuse injury in athletes, with female athletes consistently reporting higher incidence rates than males. This disparity is driven by an interplay of anatomical, hormonal, b...
LCC TENDOlNwb3J0cw~~; TENDOlNwb3J0cyBtZWRpY2luZQ~~Idioma eng
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Open Access
The Current Landscape and Future Prospects of Vaccine Manufacturing in Africa: Challenges, Innovations, and Opportunities: A Narrative Review
Artículo
Material complementario disponible Artículo DOAJ
Courage Chandipwisa et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background and Aims Africa has significant challenges in meeting its vaccination needs, including inadequate manufacturing capacity, infrastructure deficiencies, a scarcity of experienced personnel, regulatory h...
LCC LCC:MedicineIdioma eng
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Material complementario
Water-Based Exercise As a Multidimensional Non-Pharmacological Intervention In Fibromyalgia Treatment: A Narrative Review
Artículo
Acceso abierto Artículo DOAJ
Anita Jeleń et al · Nicolaus Copernicus University in Toruń · 2026 · ISSN 2450-3118
Background. Fibromyalgia, as a multidimensional syndrome, requires interventions that target multiple aspects of the disease simultaneously. This complexity underscores the importance of non-pharmacological strategies ai...
LCC TENDOlNwb3J0cw~~; TENDOlNwb3J0cyBtZWRpY2luZQ~~Idioma eng
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Open Access
Leonurine: A Multifaceted Bioactive Alkaloid—From Pharmacological Mechanisms to Clinical Translation: A Narrative Review
Artículo
Acceso abierto Artículo DOAJ
Zhouyue Gu · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and...
LCC LCC:MedicineIdioma eng
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Open Access
The Impact of High-Intensity Interval Training (HIIT) On Polycystic Ovary Syndrome (PCOS) - A Narrative Review
Artículo
Acceso abierto Artículo DOAJ
Dominika Krakowiak et al · Nicolaus Copernicus University in Toruń · 2026 · ISSN 2450-3118
The purpose of research. Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age, characterized by metabolic, hormonal, reproductive, and psychological disturbances. Its pa...
LCC TENDOlNwb3J0cw~~; TENDOlNwb3J0cyBtZWRpY2luZQ~~Idioma eng
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Open Access
What We Can Do in Infectious Keratitis, Except for Conventional Antimicrobial‐Based Therapies: Major Narrative Review
Artículo
Acceso abierto Artículo DOAJ
Kasra Cheraqpour · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background and Aims Infectious keratitis (IK) is classified as a critical ophthalmic emergency, with the potential to result in vision‐impairing complications. The treatment approach involves the use of pharma...
LCC LCC:MedicineIdioma eng
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Open Access
A mobile app (mWITH ME) for family caregivers of persons living with Alzheimer’s disease: development and initial evaluation
Artículo
Acceso abierto Artículo DOAJ
Anni Yang et al · BMC · 2026 · ISSN 1472-6947
Abstract Background The rising global aging population has increased the prevalence of Alzheimer’s disease (AD), a condition with limited treatment options, making non-pharmacological interventions essential. While mob...
LCC TENDOkNvbXB1dGVyIGFwcGxpY2F0aW9ucyB0byBtZWRpY2luZS4gTWVkaWNhbCBpbmZvcm1hdGljcw~~Idioma eng
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Open Access
CARE-HOUSE: developing a framework for conceptualizing social implications of digital health technologies in palliative care
Artículo
Acceso abierto Artículo DOAJ
Natalie Öhl et al · BMC · 2026 · ISSN 1472-684X
Abstract Background The use of digital health technologies holds potential benefits for palliative care. Their implementation is fundamentally shifting routines and care practices. These shifts entail social implications...
LCC TENDOlNwZWNpYWwgc2l0dWF0aW9ucyBhbmQgY29uZGl0aW9ucw~~Idioma eng
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Open Access
Institutional innovation in European security, and the rise of ethical-analytical centres
Artículo
Acceso institucional disponible Artículo DOAJ
Salvatore Giacomuzzi et al · V. N. Karazin Kharkiv National University · 2025 · ISSN 2310-9513
Problem: Existing approaches to European security governance remain fragmented, focusing either on traditional deterrence or on sector-specific risk management. Such compartmentalization fails to capture the systemic com...
LCC LCC:International relationsIdioma eng
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Institucional
A Review of Respiratory Infection Caused by the Human Metapneumovirus: Occurrence, Epidemiology, Pathogenesis, Public Health Outcomes, and Intervention Strategies
Artículo
Material complementario disponible Artículo DOAJ
Sylvester Chibueze Izah et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background and Aims Human metapneumovirus (hMPV) is a leading cause of acute respiratory tract infections, particularly in children, older adults, and individuals with immunocompromising conditions. Despite incr...
LCC LCC:MedicineIdioma eng
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Material complementario
AI in Point-of-Care Imaging for Clinical Decision Support: Systematic Review of Diagnostic Accuracy, Task-Shifting, and Explainability
Artículo
Material complementario disponible Artículo DOAJ
Peter Wadie et al · JMIR Publications · 2026 · ISSN 2817-1705
Abstract BackgroundArtificial intelligence (AI) integrated with point-of-care imaging is a promising approach to expand access in settings with limited specialist availability. However, no systematic review h...
LCC TENDOkNvbXB1dGVyIGFwcGxpY2F0aW9ucyB0byBtZWRpY2luZS4gTWVkaWNhbCBpbmZvcm1hdGljcw~~Idioma eng
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Accessible Authentication Mechanisms in Web and Mobile Systems for People with Disabilities: A Systematic Literature Review
Artículo
Acceso abierto Artículo DOAJ
César González-López et al · Universidad Distrital Francisco José de Caldas · 2026 · ISSN 0124-2253
In the digital age, authentication is essential for accessing the web and mobile platforms, yet many mechanisms still overlook the accessibility challenges faced by people with disabilities. In this work, a systematic li...
LCC TENDOlRlY2hub2xvZ3k~; TENDOlNjaWVuY2U~Idioma eng
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Open Access