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42 resultados encontrados.

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A systematic review of entomological outcomes and sampling approaches used in the evaluation of cluster randomised controlled trials for malaria vector control products
Artículo
Acceso abierto Artículo DOAJ
A systematic review of entomological outcomes and sampling approaches used in the evaluation of cluster randomised controlled trials for malaria vector control products
Victoria Githu et al · BMC · 2026 · ISSN 1475-2875
Abstract Background Entomological outcomes are critical for understanding the biological mechanisms and operational performance of malaria vector control interventions. However, the quality and consistency of how these o...
LCC TENDOkFyY3RpYyBtZWRpY2luZS4gVHJvcGljYWwgbWVkaWNpbmU~; TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Clinical outcomes of conduction system pacing versus right ventricular pacing in patients with atrioventricular block: a systematic review and meta-analysis of randomised controlled trials
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Clinical outcomes of conduction system pacing versus right ventricular pacing in patients with atrioventricular block: a systematic review and meta-analysis of randomised controlled trials
John Cedric Mojica et al · BMJ Publishing Group · 2026 · ISSN 2053-3624
Background Conduction system pacing (CSP) has emerged as an alternative to right ventricular pacing (RVP) for atrioventricular block (AVB) aiming to avoid ventricular dyssynchrony and adverse heart failure outcomes yet c...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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Optimal dose and type of exercise across cardiometabolic outcomes in adults with overweight or obesity: protocol for a Bayesian model-based dose–response network meta-analysis of randomised controlled trials
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Optimal dose and type of exercise across cardiometabolic outcomes in adults with overweight or obesity: protocol for a Bayesian model-based dose–response network meta-analysis of randomised controlled trials
Qiuxia Zhang et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Overweight and obesity are major global public health challenges and increase the risk of type 2 diabetes, dyslipidaemia, hypertension and cardiovascular disease. Exercise is a safe and cost-effective non-ph...
LCC LCC:MedicineIdioma eng
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PROTOCOL: A systematic review and meta‐analysis of randomised controlled trials evaluating the impact of parenting programmes for parents of adolescents (10–18 years) on adolescent mental health outcomes, positive development and the parent–adolescent relationship
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PROTOCOL: A systematic review and meta‐analysis of randomised controlled trials evaluating the impact of parenting programmes for parents of adolescents (10–18 years) on adolescent mental health outcomes, positive development and the parent–adolescent relationship
Kylie Burke et al · SAGE Publishing · 2021 · ISSN 1891-1803
LCC TENDOlNvY2lhbCBTY2llbmNlcw~~Idioma eng
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Methods for specifying the target difference in a randomised controlled trial: the Difference ELicitation in TriAls (DELTA) systematic review.
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Methods for specifying the target difference in a randomised controlled trial: the Difference ELicitation in TriAls (DELTA) systematic review.
Jenni Hislop et al · Public Library of Science (PLoS) · 2014 · ISSN 1549-1277
BackgroundRandomised controlled trials (RCTs) are widely accepted as the preferred study design for evaluating healthcare interventions. When the sample size is determined, a (target) difference is typically specified th...
LCC LCC:MedicineIdioma eng
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Calcium supplementation for prevention of pre-eclampsia in high-risk women: study protocol for a randomised triple-blind placebo-controlled trial (CaPE)
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Calcium supplementation for prevention of pre-eclampsia in high-risk women: study protocol for a randomised triple-blind placebo-controlled trial (CaPE)
Shireen Meher et al · BMC · 2026 · ISSN 1745-6215
Abstract Background Pre-eclampsia is a multisystem disorder affecting 2.8% of pregnancies in the UK. It usually presents after 20-week gestation with new-onset high blood pressure and proteinuria. Complications include e...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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The effect of smartphone-based monitoring and treatment including clinical feedback in progressed bipolar disorder: the SmartBipolar trial randomised controlled parallel-group trial
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The effect of smartphone-based monitoring and treatment including clinical feedback in progressed bipolar disorder: the SmartBipolar trial randomised controlled parallel-group trial
Maria Faurholt-Jepsen et al · SpringerOpen · 2026 · ISSN 2194-7511
Abstract Introduction A substantial proportion of patients with bipolar disorder experience daily variability in mood that seems associated with poor prognostic factors, including impaired functioning, and increased risk...
LCC LCC:Neurosciences. Biological psychiatry. Neuropsychiatry; LCC:Neurophysiology and neuropsychologyIdioma eng
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Is genicular nerve radio frequency ablation the key to improving patients’ satisfaction after total knee arthroplasty? a randomised controlled trial
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Is genicular nerve radio frequency ablation the key to improving patients’ satisfaction after total knee arthroplasty? a randomised controlled trial
Assem M. M. Ahmed et al · BMC · 2026 · ISSN 1749-799X
Abstract Background Some studies regarding patients complaining of residual pain after total knee arthroplasty (TKA) showed pain scores improvement using genicular nerve radiofrequency ablation (GNRFA). This prompted the...
LCC TENDOk9ydGhvcGVkaWMgc3VyZ2VyeQ~~; LCC:Diseases of the musculoskeletal systemIdioma eng
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Negative pressure drainage versus nasal packing in patients undergoing septoplasty: a systematic review and meta-analysis of randomized controlled trials
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Negative pressure drainage versus nasal packing in patients undergoing septoplasty: a systematic review and meta-analysis of randomized controlled trials
Abdur Rehman et al · SpringerOpen · 2026 · ISSN 2090-8539
Abstract Background Traditional nasal packing following septoplasty imposes significant patient morbidity, including pain, obligate oral breathing, and sleep disruption. Negative pressure drainage (NPD) represents a mech...
LCC TENDOk90b3JoaW5vbGFyeW5nb2xvZ3k~Idioma eng
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Adding reciprocal inhibition to conventional physiotherapy for adhesive capsulitis of the shoulder in Bangladesh: a study protocol for a randomised controlled trial evaluating pain, function and range of motion
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Adding reciprocal inhibition to conventional physiotherapy for adhesive capsulitis of the shoulder in Bangladesh: a study protocol for a randomised controlled trial evaluating pain, function and range of motion
Md Emran Hossain et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Adhesive capsulitis (frozen shoulder) is a common condition characterised by pain, stiffness and reduced function. While conventional physiotherapy (typically comprising joint mobilisation, stretching, stren...
LCC LCC:MedicineIdioma eng
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Intraoperative endoscopic pylorus dilatation during minimally invasive Ivor Lewis oesophagectomy to prevent delayed gastric conduit emptying (DGCE): protocol for the WIDE randomised controlled trial
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Intraoperative endoscopic pylorus dilatation during minimally invasive Ivor Lewis oesophagectomy to prevent delayed gastric conduit emptying (DGCE): protocol for the WIDE randomised controlled trial
Jennifer M Klasen et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Oesophageal cancer has a poor prognosis and oesophagectomy has increasingly adopted minimally invasive techniques, but delayed gastric conduit emptying (DGCE) still occurs in ~10–50% of patients, depending...
LCC LCC:MedicineIdioma eng
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Fluconazole plus flucytosine versus fluconazole alone for adults with HIV-associated cryptococcal antigenaemia identified through screening: a multi-centre phase III randomised-controlled trial
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Fluconazole plus flucytosine versus fluconazole alone for adults with HIV-associated cryptococcal antigenaemia identified through screening: a multi-centre phase III randomised-controlled trial
Kyla Murphy et al · BMC · 2026 · ISSN 1745-6215
Abstract Background Despite the expansion of antiretroviral treatment programmes, the incidence and mortality of HIV-associated cryptococcal meningitis remain high in Africa. Cryptococcal antigen (CrAg) in the blood prec...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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The independent and combined effect of price increase and price labelling on sugar-sweetened beverage vending machine sales in an Australian university: a factorial randomised controlled trial
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The independent and combined effect of price increase and price labelling on sugar-sweetened beverage vending machine sales in an Australian university: a factorial randomised controlled trial
Miranda R. Blake et al · BMC · 2026 · ISSN 1479-5868
Abstract Background No studies have examined how price increases on unhealthy drinks in university vending machines impact customer purchasing or vendor financial implications. Vending machines often display prices only ...
LCC LCC:Nutritional diseases. Deficiency diseases; LCC:Public aspects of medicineIdioma eng
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Testing interventions to increase participation in the Australian National Bowel Cancer Screening Program among persistent never-screeners: study protocol for a randomised controlled trial
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Testing interventions to increase participation in the Australian National Bowel Cancer Screening Program among persistent never-screeners: study protocol for a randomised controlled trial
Jennifer G McIntosh et al · BMC · 2026 · ISSN 1745-6215
Abstract Background Bowel cancer screening using faecal immunochemical tests (FIT) can detect early signs of bowel cancer and pre-cancerous adenoma. Early detection enables early diagnosis and treatment thereby reducing ...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Effects of a device-measured physical activity intervention on visual outcomes, including contrast sensitivity, and glycaemic control in individuals with abnormal glucose tolerance: a pilot randomised trial post-CarMeR study
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Effects of a device-measured physical activity intervention on visual outcomes, including contrast sensitivity, and glycaemic control in individuals with abnormal glucose tolerance: a pilot randomised trial post-CarMeR study
Ebenezer Oduro Antiri et al · BMC · 2026 · ISSN 2055-5784
Abstract Background Abnormal glucose tolerance (AGT), a summary term for prediabetes and diabetes, is a significant public health concern in sub-Saharan Africa, where diabetes-related complications like retinopathy are u...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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How can innovative trials in juvenile idiopathic arthritis serve the unmet needs of patients?
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How can innovative trials in juvenile idiopathic arthritis serve the unmet needs of patients?
Joshua L Bennett et al · BMC · 2026 · ISSN 1478-6362
Abstract Juvenile idiopathic arthritis (JIA) comprises a heterogeneous group of childhood-onset inflammatory arthritides that remain challenging to treat. An expanding range of biologic and targeted synthetic disease-mod...
LCC LCC:Diseases of the musculoskeletal systemIdioma eng
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Tr14 gel compared to diclofenac gel after acute unilateral ankle sprain: an Individual Patient Data (IPD) meta-analysis of two multi-center trials
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Tr14 gel compared to diclofenac gel after acute unilateral ankle sprain: an Individual Patient Data (IPD) meta-analysis of two multi-center trials
J. Vester et al · BMC · 2026 · ISSN 1471-2474
Abstract Background Traumeel (Tr14) and diclofenac gels are commonly prescribed topical treatments for Grade I-II acute lateral ankle sprain (LAS). A meta-analysis of two multi-center trials was performed to compare thei...
LCC LCC:Diseases of the musculoskeletal systemIdioma eng
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PARTIAL: study protocol for a clinical and cost-effectiveness of complex PARTIAL vs radical nephrectomy for clinically localised renal cell carcinoma randomised trial
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PARTIAL: study protocol for a clinical and cost-effectiveness of complex PARTIAL vs radical nephrectomy for clinically localised renal cell carcinoma randomised trial
Diana Johnson et al · BMC · 2026 · ISSN 1745-6215
Abstract Background Localised renal cell carcinoma is treated with radical nephrectomy (RN) or partial nephrectomy (PN). Nephron-sparing PN increases preservation of renal function, reducing incidence of end stage renal ...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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From emergency room to neurorehabilitation: a systematic review and meta-analysis of contemporary multidisciplinary strategies in traumatic brain injury management
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From emergency room to neurorehabilitation: a systematic review and meta-analysis of contemporary multidisciplinary strategies in traumatic brain injury management
Ravi Yadav et al · SpringerOpen · 2026 · ISSN 2520-8225
Abstract Background Traumatic brain injury (TBI) needs inter-disciplinary care through pre-hospital resuscitation, emergency and neurosurgical care, neurocritical care, and structured neurorehabilitation to maximize surv...
LCC TENDOlN1cmdlcnk~; LCC:Neurosciences. Biological psychiatry. NeuropsychiatryIdioma eng
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A python’s embrace? Insurance and the global clinical trial
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A python’s embrace? Insurance and the global clinical trial
Janelle Winters · BMC · 2026 · ISSN 1478-4505
Abstract Background Regulatory barriers present significant challenges to clinical trial approval during both “peacetime” and pandemics, particularly for multi-country clinical trials sponsored by academic institutio...
LCC LCC:Public aspects of medicineIdioma eng
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Understanding trial informativeness in digital mental health: perspectives from researchers and lived experience experts
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Understanding trial informativeness in digital mental health: perspectives from researchers and lived experience experts
Alexia Jeayes et al · BMC · 2026 · ISSN 1745-6215
Abstract Background Randomised controlled trials (RCTs) are often considered the gold standard in research design to determine clinical and cost-effectiveness, and yet the majority are not considered “informative” or...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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The long-term cardiovascular safety and efficacy of glucagon-like peptide-1 (GLP-1) receptor agonists in high-risk cardiovascular populations: a systematic review and meta-analysis
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The long-term cardiovascular safety and efficacy of glucagon-like peptide-1 (GLP-1) receptor agonists in high-risk cardiovascular populations: a systematic review and meta-analysis
Kezia Peter et al · BioMed Central · 2026 · ISSN 3059-4057
Abstract Background Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used for the management of type 2 diabetes and obesity, yet their long-term cardiovascular effects in high-risk populations continue to ...
LCC LCC:Specialties of internal medicineIdioma eng
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Characteristics and birth outcomes of pregnant adolescents compared to older women: An analysis of individual level data from 140,000 mothers from 20 RCTs
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Characteristics and birth outcomes of pregnant adolescents compared to older women: An analysis of individual level data from 140,000 mothers from 20 RCTs
Akseer, Nadia et al · Elsevier · 2022 · ISSN 2589-5370
Background: Adolescence is a critical period of maturation when nutrient needs are high, especially among adolescents entering pregnancy. Using individual-level data from 140,000 participants, we examined socioeconomic, ...
Idioma eng
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Cognitive‐Behavioural Interventions for Preventing Youth Gang Involvement for Children and Young People (7‐16)
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Cognitive‐Behavioural Interventions for Preventing Youth Gang Involvement for Children and Young People (7‐16)
Ms Herrick Fisher et al · SAGE Publishing · 2008 · ISSN 1891-1803
Research indicates that youth who join gangs are more likely to be involved in delinquency and crime, particularly serious and violent offences, compared to non‐gang youth and non‐gang delinquent youth. Research also...
LCC TENDOlNvY2lhbCBTY2llbmNlcw~~Idioma eng
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