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Abstract Background Lymphatic filariasis (LF) is a vector-borne parasitic disease that is being targeted for elimination through mass drug administration (MDA). The co-distribution of Loa loa in Central Africa poses a si...

Abstract Generative deep learning models have demonstrated significant potential in designing drug-like molecules. However, medicinal chemistry typically requires generating analogues that combine structural similarity w...

Abstract Background Treatment is indicated in dogs with preclinical degenerative mitral valve disease (DMVD) and cardiomegaly (stage B2). This is best diagnosed using echocardiography; however, relying upon this limits a...

Niche dimensionality provides a general theoretical explanation for biodiversity-more niches, defined by more limiting factors, allow for more ways that species can coexist. Because plant species compete for the same set...

Abstract Background A treatment of chronic kidney disease (CKD)‐associated anemia in cats is needed. SB‐001 is an adeno‐associated virus‐vectored (AAV)‐based gene therapeutic agent that is administered intramus...

Abstract Background Magnetic resonance imaging is the method of choice for diagnosing spinal cord neoplasia, but the accuracy of designating the relationship of a neoplasm to the meninges and agreement among observers is...

Abstract Background Chronic kidney disease (CKD) frequently causes death in older cats; its early detection is challenging. Objectives To build a sensitive and specific model for early prediction of CKD in cats using art...

Abstract Objective To conduct a systematic review of external validation studies on the use of different Artificial Intelligence algorithms in breast cancer screening with mammography. Data source Our systematic revi...

Objective. To assess non-participation bias in a survey ofmale sexual behavior. Material and methods. A householdsurvey was carried out in 1992-1993 using a probabilitysampling frame in Mexico City. Demographic variables...

Abstract Background Hypoxia is a key driver of fibrosis and is associated with capillary rarefaction in humans. Objectives Characterize capillary rarefaction in cats with chronic kidney disease (CKD). Animals Archival ki...

Abstract Background Hydromyelia is a common magnetic resonance imaging (MRI) finding associated with compressive myelopathy caused by intervertebral disc extrusion (IVDE). Objectives To describe the MRI features of hydro...

This study evaluates how sociodemographic and psychological variables influence the intention in participating in future waves of a positive psychology longitudinal research. Participants were 2551 Brazilian subjects (63...

Abstract Bronchopulmonary dysplasia (BPD) is a common complication among preterm neonates, with portable X-ray imaging serving as the standard diagnostic modality in neonatal intensive care units (NICUs). However, lung m...

Abstract Background Current tests for diagnosis and differentiation of lymphoplasmacytic enteritis (LPE) and small cell lymphoma (SCL) in cats are expensive, invasive, and lack specificity. The identification of less inv...

Abstract Background Dietary protein and phosphorus (P) restriction is the mainstay for nutritional management of chronic kidney disease (CKD). However, adequate restriction levels for cats with early CKD remain unclear. ...

Abstract The primary goal of fluid therapy is to optimize cardiac output in preload-dependent patients. However, all types of fluid solutions can have side effects. Oral water intake regulates fluid absorption, leading t...

Abstract Background Three‐dimensional computed tomographic (CT) evaluation of the cervical vertebral column enables more accurate identification of osseous and soft tissue lesions than traditional latero‐lateral radi...

Design strategies for improving terahertz (THz) quantum cascade lasers (QCLs) in the 5–6 THz range are investigated numerically and experimentally, with the goal of overcoming the degradation in performance that occu...

Abstract Background Plasma total magnesium concentration (tMg) is a prognostic indicator in cats with chronic kidney disease (CKD), shorter survival time being associated with hypomagnesemia. Whether this risk factor is ...

RESUMO O objetivo do presente estudo é investigar e analisar a diversidade florística de Dioscoreaceae na Reserva Biológica do Alto da Serra de Paranapiacaba para aumentar o conhecimento florístico de Dioscoreales de...

In the context of global warming, droughts are increasingly threatening our societies. They last for months or even years, affecting wide areas and large numbers of people, with single drought events sometimes causing ec...

Abstract Background Cardiac disease is an important cause of morbidity and mortality in Irish Wolfhounds (IWs), but its prevalence and clinical characteristics in North American IWs are incompletely described. Hypothesis...

Abstract Background Despite limited evidence of efficacy, antibiotic treatment is still frequently prescribed in dogs with uncomplicated acute diarrhea (AD). Objective To assess whether amoxicillin‐clavulanic acid has ...

Abstract Background Recent studies have shown similar efficacy of oral supplementation of cobalamin compared to injectable supplementation in dogs, but few prospective, randomized studies have been published. Objectives ...