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Thrombotic thrombocytopenic purpura (TTP) is a rare, life threatened disease. It is characterized by fever, variable neurological manifestations, progressive renal failure, microangiopathic hemolytic anemia and thrombocy...

Materias / palabras clave: psoriasis; connective tissue; cutaneous lupus erythematosus

In patients with systemic lupus erythematosus (SLE) avascular osteonecrosis can occur either because of a complication of treatment or association with antiphospholipid antibody (APA). In this report, a patient with SLE ...

Abstract Objectives To evaluate the prevalence, associated factors, and prognostic performance of NIH activity index–defined interstitial inflammation (NIH-TII) and interstitial fibrosis and tubular atrophy (IFTA) in l...

Abstract Background Pulmonary hypertension (PH) is a serious and potentially life-threatening complication of systemic lupus erythematosus (SLE). Functional characterization may facilitate the differentiation of the hete...

Classic polyarteritis nodosa (cPAN) is a systemic necrotizing vasculitis of medium-sized muscular arteries. Glomerular involvement is not expected in the course of cPAN. Herein, we describe a case of cPAN with glomerular...

Objective This study aimed to describe the clinical and neuroimaging characteristics and 120-day outcomes in neuropsychiatric systemic lupus erythematosus patients. Methods This prospective study involved 32 patients wit...

Atypical hemolytic uremic syndrome (aHUS) is a disorder characterized by a propensity to thrombotic microangiopathy (TMA) due to defective regulation of the alternative complement pathway. Mutations in genes encoding com...

Objective Patients with SLE have increased risk of both clinical cardiovascular disease (CVD) and subclinical atherosclerosis. Reports have shown that controlling CVD risk factors reduces subclinical plaque progression i...

Abstract Lupus retinopathy (LR) is one of the most frequent and serious ocular complications of systemic lupus erythematosus (SLE), because it may cause irreversible visual impairment. The aim of this study was to evalua...

ABSTRACT Introduction Systematic lupus erythematosus is a complex fundamental autoimmune disease with relapsing‐remitting course and spectrum of disease ranging from mild to life‐threatening illness. Approximately ha...

Renal involvement in systemic lupus erythematosus is a frequent and serious complication that significantly increases morbidity and mortality. Despite all studies and usage of new drugs, treatment of lupus nephritis cont...

Abstract Background Lupus nephritis (LN) is driven by podocyte pyroptosis triggered by NLRP3 inflammasome activation, yet the dual regulatory mechanisms—transcriptional control by the AP-1 complex (c-JUN/c-FOS heterodi...

Abstract Background This study was motivated by the high prevalence of anemia of inflammation (AI) in systemic lupus erythematosus (SLE) and the poorly explored potential link between the underlying inflammatory drive an...

O intervalo pós-morte (IPM) é um instrumento importante de diagnóstico relacionado à prática forense. O uso de insetos tem sido relatado como um modo eficiente para estimá-lo, quando o cadáver encontra-se em está...

Objective. To assess risk factors associated with systemiclupus erythematosus (SLE) in the Mexican population. Materialand Methods. A case-control study was conductedon June 1996, at the Reumathology Clinic of Hospital d...

Materias / palabras clave: Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy

Abstract This study aims to characterized high-resolution HLA alleles in Thai SLE patients and investigate their clinical correlations.The 6 digits HLA allele imputation was conducted using previously published Thai geno...

Systemic lupus erythematosus (SLE) is an autoimmune disorder. One of the most typical aspects of SLE is renal involvement. Lupus nephritis is a serious disease whose prognosis can usually be improved dramatically by trea...

Lupus nephritis is an infl ammation of the kidney caused by systemic lupus erythematosus (SLE). Lupus nephritis is a frequent complication of SLE that increases mortality and morbidity. Minimal glomerular lesions, mesang...

ABSTRACT The cGAS‐STING pathway is emerging as an essential driver in systemic lupus erythematosus (SLE). Here, we characterize the key signature of cGAS‐STING pathway and its roles in SLE by leveraging large‐scale...

Systemic Lupus Erythematosus (SLE) is a prevalent disease that shows all the characteristics of an autoimmune pathology. The developments in the pathogenic factors in SLE provide new insights to the treatment of SLE and ...

Posterior reversible encephalopathy syndrome (PRES) is characterised with neurological symptoms and typical radiological appearances. Hypertension is the most common cause of PRES. Systemic lupus erythematosus is a rare ...