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50 resultados encontrados.

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Heat-related health impacts in ASEAN countries: A scoping review
Artículo
Material complementario disponible Artículo DOAJ
Htoo Wai Aung et al · Elsevier · 2026 · ISSN 2665-9727
Approximately 670 million residents in the ASEAN region face heat-related health risks including synergistic effects with air pollution. Despite health impacts of heat studies existed in individual countries, a regionwid...
LCC TENDOkVudmlyb25tZW50YWwgc2NpZW5jZXM~Idioma eng
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High efficiency and sustainability of PVDF membrane in wastewater treatment and reuse
Artículo
Material complementario disponible Artículo DOAJ
Fuxing Lin et al · KeAi Communications Co., Ltd · 2026 · ISSN 2949-7361
To address the challenges of membrane fouling, short service life, and unstable performance associated with PVDF membranes in wastewater treatment and reuse, this study proposes a multi-dimensional collaborative optimiza...
LCC TENDOkVudmlyb25tZW50YWwgZW5naW5lZXJpbmc~; TENDOkVudmlyb25tZW50YWwgc2NpZW5jZXM~Idioma eng
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Integrated analysis of ATAC-seq and RNA-seq reveals the TCP-ARF molecular module related to pathogenic process of phytoplasma infection in Paulownia fortunei
Artículo
Acceso abierto Artículo DOAJ
Shunmou Huang et al · BMC · 2026 · ISSN 1471-2164
Abstract Background Witches’ broom is an important disease of the Paulownia fortunei. Understanding the pathogenesis of witches’ broom is a prerequisite for its prevention and control. Phytoplasma is the pathogen of ...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:GeneticsIdioma eng
Acceso abiertoRuta libre sin proxy. Acceso recomendado cuando no hay suscripción activa.
Open Access
Integrating ultrafiltration fractionation and click chemistry for the construction of lignin-derived dye dispersants
Artículo
Material complementario disponible Artículo DOAJ
Xiao Jiang et al · KeAi Communications Co., Ltd · 2026 · ISSN 2772-4433
Lignin, the most abundant aromatic polymer from nature, represents a promising feedstock for sustainable functional materials. Yet its intrinsic structural heterogeneity and broad molecular weight distribution limit its ...
LCC TENDOkNoZW1pY2FsIHRlY2hub2xvZ3k~Idioma eng
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Nicotine promotes cardiac fibrosis by regulating miR-125b-5p maturation via HNRNPA2B1-mediated METTL14-dependent m⁶A methylation: therapeutic reversal by cinacalcet HCl
Artículo
Material complementario disponible Artículo DOAJ
Hui-hui Wu et al · BMC · 2026 · ISSN 1479-5876
Abstract Background Cardiac fibrosis is a pivotal pathological process driving adverse cardiac remodeling and a defining feature of end-stage heart disease. Nicotine, a principal constituent of tobacco products, is now r...
LCC LCC:MedicineIdioma eng
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Protein S-palmitoylation: Dynamic regulatory networks, physiological functions, and new frontiers in targeted therapy
Artículo
Acceso abierto Artículo DOAJ
Yi Wang et al · Elsevier · 2026 · ISSN 1096-1186
S-palmitoylation, a key reversible lipid post-translational modification, entails the covalent conjugation of palmitic acid chains to the thiol groups of cysteine residues in proteins. This modification modulates protein...
LCC LCC:Therapeutics. PharmacologyIdioma eng
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Open Access
Regulation of histone methylation on secondary metabolite production in phytopathogenic fungi
Artículo
Acceso abierto Artículo DOAJ
Xuwen Hou et al · BMC · 2026 · ISSN 2524-4167
Abstract Fungal histone methylation modification (HMM) includes methylation and demethylation at the histone lysine/arginine residues, which are catalyzed by the methyltransferases (HMTs) and demethylases (HDMs) of histo...
LCC TENDOlBsYW50IGN1bHR1cmU~Idioma eng
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Open Access
The enzymatic mechanisms of lactylation and its role in gynecological diseases: a comprehensive review
Artículo
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Min Zhang et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Lysine lactylation (Kla) is a novel form of post-translational modification. It utilizes lactate as its core substrate. Through an enzymatic regulatory network, it mediates modifications of both histones and non-histone ...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Open Access
Unraveling the complexity of the histone code: implications for gene regulation and disease
Artículo
Acceso abierto Artículo DOAJ
Kiera L. Malone et al · BMC · 2026 · ISSN 1474-760X
Abstract Histone post-translational modifications epigenetically regulate gene expression by modulating nucleosome structure and DNA accessibility. This review outlines how unique patterns of modifications on canonical ...
LCC LCC:Biology (General); LCC:GeneticsIdioma eng
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Open Access
A genetic toolkit for the human gut bacterium Mediterraneibacter gnavus identifies capsular polysaccharides as a competitive colonization factor
Artículo
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Nozomu Obana et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract Mediterraneibacter gnavus is a human symbiotic gut bacterium whose abundance often increases in patients with various diseases, such as active inflammatory bowel disease (IBD). However, the genetic factors gover...
LCC TENDOlNjaWVuY2U~Idioma eng
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Open Access
An Advanced Review Focusing on the Production of Secondary Plant Biomass-Derived Cellulose Nanocrystal-Activated Char-Based Polyfunctional Bionanoadsorbents for Bulk-Scale Industrial Wastewater Purification: A Fixed-Bed Column Adsorption Study With Mechanism and Modeling
Artículo
Acceso abierto Artículo DOAJ
Md. Mahmudur Rahman et al · Wiley · 2026 · ISSN 1687-9430
Currently, a massive expanse of wastewater is generated and ejected directly into the environment owing to widespread industrialization, hasty fluctuating technologies, and excess demand of the overgrowing population. Th...
LCC TENDOkNoZW1pY2FsIHRlY2hub2xvZ3k~Idioma eng
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Open Access
Barriers to hypertension management in a developing country: a qualitative study among patients with hypertension at the National Hospital of Sri Lanka
Artículo
Acceso abierto Artículo DOAJ
Priyanga Ranasinghe et al · BMC · 2026 · ISSN 1471-2458
Abstract Background A rapidly rising prevalence of hypertension (HTN) is observed in low-and-middle-income countries but few studies explore factors such as attitudes and beliefs, experiences and social and cultural cond...
LCC LCC:Public aspects of medicineIdioma eng
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Open Access
Dysregulated m6A RNA methylation in tuberculosis: association with altered methyltransferase expression and immune responses
Artículo
Acceso abierto Artículo DOAJ
Yunyi Xu et al · BMC · 2026 · ISSN 1471-2334
Abstract Objective Tuberculosis (TB) remains a global health threat with an incompletely understood pathogenesis. The RNA epigenetic modification N6-methyladenosine (m6A) is a key regulator of immune responses in various...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Open Access
Effect of low-temperature stress on sperm DNA methylation and oxidative damage during cryopreservation of Tibetan pig semen
Artículo
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Mengqi Duan et al · Veterinary World · 2026 · ISSN 0972-8988
Background and Aim: Cryopreservation of boar semen is widely used for genetic conservation and artificial insemination; however, it induces oxidative stress and molecular alterations that compromise sperm function. Epige...
LCC LCC:Animal culture; TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Open Access
Geological characteristics and enrichment-accumulation patterns of coalbed methane within the Jurassic strata in the Miquan area along the southern margin of the Junggar Basin
Artículo
Acceso abierto Artículo DOAJ
Luofei WU et al · Editorial Office of Coal Geology & Exploration · 2026 · ISSN 1001-1986
ObjectiveThe southern margin of the Junggar Basin (also referred to as the southern Junggar) possesses abundant medium- to low-rank coalbed methane (CBM) resources, with significant progress achieved in CBM exploration a...
LCC TENDOkdlb2xvZ3k~; TENDOk1pbmluZyBlbmdpbmVlcmluZy4gTWV0YWxsdXJneQ~~Idioma zho
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Open Access
Incorporating angina into the H2FPEF score improves diagnostic performance for HFpEF in women
Artículo
Acceso abierto Artículo DOAJ
N Charlotte Onland-Moret et al · BMJ Publishing Group · 2026 · ISSN 2053-3624
Background and aims The Heavy, Hypertensive, Atrial fibrillation, Pulmonary hypertension, Elder, Filling pressure (H2FPEF) score is a widely used diagnostic tool for heart failure with preserved ejection fraction (HFpEF)...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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Indicators of Oxidative Stress in Rat Brain Tissue Under Conditions of Prolonged Arterial Hypertension and Its Correction With Different Generations of Beta-blockers
Artículo
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Igor Belenichev et al · Igor Sikorsky Kyiv Polytechnic Institute · 2026 · ISSN 2616-177X
Background. The significant increase in the number of patients with arterial hypertension both worldwide and in our country necessitates a more detailed study of the pathogenetic features of changes that occur in target ...
LCC LCC:Biology (General)Idioma eng
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Open Access
Performance Characterization of Rubberized Asphalt Mixtures Incorporating Waste Tire and Solid Natural Rubber
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Ramadhani Ramadhani et al · Mustansiriyah University/College of Engineering · 2026 · ISSN 2520-0917
The performance of asphalt mixtures modified with 7% and 10% waste tire and solid natural rubber is assessed in this study, along with the effects of replacing fine aggregate with these materials. According to binder tes...
LCC LCC:Engineering (General). Civil engineering (General)Idioma ara
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Population epigenetics: Historical notes and applications in human health
Artículo
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Sergio Russo Matioli · Sociedade Brasileira de Genética · 2026 · ISSN 1678-4685
Abstract A key factor contributing to the success of Darwin and Wallace’s theory of biological evolution by natural selection was its population-level perspective. This conceptual framework was not immediately adopted,...
LCC LCC:GeneticsIdioma eng
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Open Access
Quantifying vacuum-like jets in heavy-ion collisions: a machine learning study
Artículo
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Miguel Crispim Romão et al · SpringerOpen · 2026 · ISSN 1434-6052
Abstract The modification of jets by interaction with the quark gluon plasma has been extensively established through the comparison of observables computed for samples of jets produced in nucleus-nucleus collisions and ...
LCC TENDOkFzdHJvcGh5c2ljcw~~; TENDOk51Y2xlYXIgYW5kIHBhcnRpY2xlIHBoeXNpY3MuIEF0b21pYyBlbmVyZ3kuIFJhZGlvYWN0aXZpdHk~Idioma eng
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RNA methylation in autoimmune rheumatic diseases: mechanisms and therapeutic potential
Artículo
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Yuyao Wang et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Autoimmune rheumatic diseases (ARDs), often characterized by pain, constitute a diverse group of autoimmune conditions involving inflammation-mediated injuries to bones, joints, surrounding connective tissues, and occasi...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Open Access
Targeting m6A RNA methylation to sensitize cancer cells to DNA-damaging therapies
Artículo
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Bianca Cesaro et al · Springer · 2026 · ISSN 2730-6011
Abstract N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic mRNA and plays a crucial role in post-transcriptional gene regulation. Recent studies have revealed that m6A modification is dysr...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Trans-catheter versus open surgical aortic valve replacement in severe symptomatic aortic stenosis
Artículo
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Mohammed Fawzy Eltaweel et al · BMC · 2026 · ISSN 1749-8090
Abstract Objectives The objectives of this study were: (1) to compare the incidence of effective orifice area (EOA) after either the trans-catheter and surgical aortic valve replacement (SAVR); and (2) to assess the impa...
LCC TENDOlN1cmdlcnk~; LCC:AnesthesiologyIdioma eng
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UBE2M promotes malignant phenotypes of prostate cancer through mediating NAA10 neddylation
Artículo
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Qixia Wang et al · BMC · 2026 · ISSN 1479-5876
Abstract Background Prostate cancer (PCa) is a common malignant tumor in men, with a high incidence rate, posing a serious threat to human health and quality of life. Neddylation is a major post-translation modification,...
LCC LCC:MedicineIdioma eng
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Open Access