Buscar recursos académicos

Underwater gas pipelines are vital for energy transportation but are often subjected to harsh environments, and any leakage can have significant environmental consequences. Substantial underestimation of gas plume format...

Human induced pluripotent stem cells (iPSCs) are transforming adoptive cell therapy by combining unlimited self-renewal, broad differentiation potential, and high amenability to genome engineering. These attributes make ...

Fungi are ubiquitous across nearly all habitats and play pivotal roles in maintaining ecological sustainability. Understanding the composition and functional roles of active fungal communities is essential for elucidatin...

Neuroinflammation is a key immunological driver of spinal sensitization and the transition from acute to chronic pain. Although mechanical interventions can reduce pain, the immuno-inflammatory mechanisms linking mechani...

This data paper describes bacterial and fungal communities associated with the sponge Chondrilla nucula collected from two Eastern Mediterranean populations (North and South Aegean Sea) and maintained under controlled co...

Abstract Background Drug-induced liver injury (DILI) remains a significant barrier to the safe and efficient use of antimalarial medicines. Many promising compounds fail in late-stage development or post-marketing owing ...

This study investigates the functional modification of ternary ethylene-propylene rubber (EPDM) with benzamine phenol formaldehyde (BPFO) to enhance its properties and compatibility with butadiene-nitrile rubber (NBR). S...

Pipelines are used to transport water, oil, and gas so regular inspection is important to avoid cracks, corrosion, leakage and blockages. Manual inspection is slow, risky and cannot always detect internal damage. This pa...

BackgroundDepressive disorders are clinically heterogeneous and mechanistically complex psychiatric conditions. Transcranial direct current stimulation (tDCS), a key non-invasive neuromodulation technique, has expanded r...

Accurate RNA quantification at the single-cell level is critical for understanding the dynamics of gene expression and regulation across space and time. Single molecule FISH (smFISH), such as RNAscope, provides spatial a...

The emergence of the Metaverse as a persistent, immersive, and interoperable digital ecosystem introduces system-level challenges in identity management, security, and privacy protection across networked extended reality...

Water information systems (ISs) are essential for sustainable water management but are often constrained by fragmented, heterogeneous, and rapidly evolving data. Advances in generative artificial intelligence (GenAI), pa...

As Machine Learning Operations (MLOps) adoption accelerates, systematic integration of explainability is imperative for reliability, transparency, and continuous quality assurance. This paper presents a scoping review ex...

Transposable elements (TEs) make up almost half of the human genome and are among its most densely methylated regions. Their epigenetic silencing is crucial for genomic stability and immune homeostasis, and accumulating ...

Abstract Cracks, especially small cracks are difficult to be detected in oil and gas transportation pipelines buried underground or covered with layers of material by using the traditional ultrasonic inspection technique...

This study explores women’s leadership in higher education through a synthesis of research on leadership trends, organizational challenges, and institutional op-portunities influencing progression into senior academic ...

An account is given of the development of the SHELX system of computer programs from SHELX-76 to the present day. In addition to identifying useful innovations that have come into general use through their implementation...

Abstract Array programming provides a powerful, compact and expressive syntax for accessing, manipulating and operating on data in vectors, matrices and higher-dimensional arrays. NumPy is the primary array programming l...

MOTIVATION: Testing for correlations between different sets of genomic features is a fundamental task in genomics research. However, searching for overlaps between features with existing web-based methods is complicated ...

Multiple sequence alignments are fundamental to many sequence analysis methods. Most alignments are computed using the progressive alignment heuristic. These methods are starting to become a bottleneck in some analysis p...

The CCP4 (Collaborative Computational Project, Number 4) software suite is a collection of programs and associated data and software libraries which can be used for macromolecular structure determination by X-ray crystal...

BACKGROUND: The quality of automated gene prediction in microbial organisms has improved steadily over the past decade, but there is still room for improvement. Increasing the number of correct identifications, both of g...

UNLABELLED: The multiplex capability and high yield of current day DNA-sequencing instruments has made bacterial whole genome sequencing a routine affair. The subsequent de novo assembly of reads into contigs has been we...

BACKGROUND: SAMtools and BCFtools are widely used programs for processing and analysing high-throughput sequencing data. They include tools for file format conversion and manipulation, sorting, querying, statistics, vari...