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Background: Staphylococcus spp. are major pathogens causing diverse clinical infections. Evaluating their phenotypic characteristics and antimicrobial response across different culture media is essential for accurate dia...

Abstract Introduction In Tanzania, despite the progress in HIV testing and counseling, 39.4% of people living with HIV aged ≥ 15 years were unaware of their HIV status in 2017. HIV testing is a crucial entry point ...

The global rise of multidrug-resistant bacteria necessitates the development of new antimicrobials and faster diagnostic tools. Conventional antimicrobial susceptibility testing is slow, relying on culture-based methods ...

PurposePreimplantation genetic testing for aneuploidy (PGT-A) is essential for selecting embryos free from chromosomal abnormalities before transfer. However, challenges such as detection failures, mosaicism, and the lim...

Colorimetric assays offer a low-cost, accessible means of diagnostic testing but often suffer from subjective interpretation and variability caused by inconsistent imaging conditions. To address these challenges, we pres...

Vaccination is widely used to control foot-and-mouth disease (FMD), necessitating robust approaches for evaluating vaccine potency to ensure a consistent supply of effective and safe vaccines. Traditional (in vivo) poten...

Abstract Background A core tenet of implementation science is early planning for implementation with invested partners. For health systems, aligning workflows and strategies to the local context and ensuring that the int...

Regression testing plays a critical role in ensuring the reliability and quality of software following continuous integration and development. However, executing all test cases during regression testing can be time-consu...

A 5-year-old female presented at age 2 with recurrent respiratory and ear infections, aphthous ulcers, and severe neutropenia (absolute neutrophil count [ANC] = 400 cells/mcl). Immunological testing at age 4 showed neutr...

Abstract Background Trauma is among the leading causes of death and disability in Malawi and accounts for a substantial proportion of emergency admissions at tertiary hospitals. However, injured patients presenting for t...

Abstract BackgroundWith the advent of new vaccines, including the COVID-19 vaccines introduced during the recent pandemic, the need for near real-time active surveillance has increased to support timely regul...

The microstructure evolution and performance characteristics of the heat-affected zone (HAZ) in laser welding of 10Ni5CrMoV steel are investigated. By designing novel thermal simulation specimens and utilizing a thermal ...

ABSTRACT Background The COVID‐19 pandemic has caused massive devastation worldwide, and its effects still persist. Managing the early stages was difficult, but scientists worked tirelessly to control it. The emergence ...

Abstract Background DNA methylation analysis provides a promising triage strategy for cervical intraepithelial neoplasia (CIN) and cancer detection following Human Papillomavirus (HPV) testing on self-collected samples, ...

Abstract Objective Given the distinct intratumoral heterogeneity of glioblastoma (GB) and solitary brain metastasis (SBM), habitat-based radiomics derived from neurite orientation dispersion and density imaging (NODDI) m...

BackgroundPyoderma gangrenosum (PG) is a rare ulcerative neutrophilic dermatosis that can be associated with primary immunodeficiencies. Its pathogenesis is incompletely understood, but it has been increasingly reported ...

Purpose – This research and development aims to 1 develop a Moodle-based LMS system for Geography that is feasible, 2 determine the practicality of LMS in learning, and 3 test the effectiveness of LMS in improving lear...

Abstract Accurate specimen preparation is essential for biomechanical push-out testing of bone–implant interfaces. A common source of error arises when implants such as pins or screws are not cut exactly perpendicular ...

Abstract Introduction In December 2022, the zero - COVID strategy was amended, eliminating mandatory testing and isolation. The purpose of this study was to explore the effectiveness of targeted prevention measures in a ...

Objective To investigate the influence of water on the monotonic and fatigue strength of a lithium disilicate glass-ceramic. Methods Ninety bar-shaped specimens (1.0 × 1.0 × 12.0 mm) were prepared from Advanced Lithium...

Abstract Malaria in pregnancy remains a significant public health challenge in sub-Saharan Africa, with adverse health outcomes for mothers and foetuses. This study assessed knowledge, attitudes, practices and factors as...

IntroductionAdenosine deaminase–deficient severe combined immunodeficiency (ADA-SCID) is an autosomal recessive disorder comprising ∼15% of SCID cases. Newborn screening (NBS) relies on T cell receptor excision circl...

Objective This follow-up study examined changes in motor performance over 6 months among preschool children in Tyrol, Austria, initially screened for motor difficulties suggestive of developmental coordination disorder. ...

Abstract Background Circulating cell-free DNA (cfDNA) is a promising biomarker for non-invasive early cancer detection. We integrated methylation entropy, a measure of DNA methylation heterogeneity, with other cfDNA feat...