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Abstract Background Holmes tremor (HT) is a rare, symptomatic movement disorder characterized by a low-frequency tremor present at rest, with postural and intentional components. It is typically caused by combined lesion...

Mild cognitive impairment (MCI) and dementias, such as Alzheimer’s disease (AD)-induced dementia and vascular dementia, are major public health burdens. The blood-brain barrier (BBB) disruption, systemic inflammation, ...

Background and purposeThe aging brain is particularly sensitive to alterations in selenium status. Selenium deficiency has been associated with impaired neural function, cognitive decline, and increased vulnerability to ...

A growing number of studies are now utilizing human organotypic brain slice cultures (OBSC), enabled by improved long-term culture protocols that support the investigation of human-specific cellular physiology. Human OBS...

Extensive research has demonstrated that music enhances cognitive functions, such as learning, reasoning, and memory. This study investigated the influence of music on short- and long-term memory while learning through t...

Abstract Fetal growth restriction (FGR) occurswhen the fetus does not reach its intrauterine potential for growth and development as a result of compromise in placental function. It is a condition that affects 5 to 10% o...

Abstract Growing evidence indicates a crucial role of the gut microbiota in physiological functions. Gut-brain axis imbalance has also been associated with neuropsychiatric and neurodegenerative disorders. Studies have s...

Neurological disorders such as post-stroke hemiplegia, spinal cord injury, and Parkinson disease represent a major global health burden. Brain-computer interface (BCI), which creates direct communication pathways between...

Brain-computer interface (BCI) is a neuro-engineering technology that establishes a direct communication pathway between the brain and external devices. It can realize bidirectional information interaction between the br...

IntroductionHuman space exploration is progressing into an unprecedented era characterized by extended-duration missions, the establishment of permanent lunar bases, and planned crewed voyages to Mars. These activities i...

BackgroundFrailty is significantly more prevalent in individuals with Parkinson’s disease (PD) than in general population, yet the underlying neuropathophysiological mechanisms remain poorly understood. This study aime...

BackgroundCurrent prognostic models for cerebral venous sinus thrombosis (CVST) inadequately predict long-term cognitive and functional outcomes, focusing primarily on survival. We aimed to develop and validate a simple,...

Objective This study aimed to explore the influence of the angiotensin-(1–7)/Mas receptor and angiotensin II/angiotensin II type 1 receptor pathways on pyroptosis during sepsis and their subsequent effects on cognitive...

Male mice on a diet supplemented with thioproline (l-thiazolidine-4-carboxylic acid), a physiological metabolite of 5-hydroxytryptamine, at 2.0 g/kg of food from 28 weeks of age and for their entire life, showed a 23-29%...

Introduction: The study of patients with acquired brain injury shows the existence of several double dissociations in the calculation system. In this paper, we focus on the double dissociation observed between oral and w...

The brain exhibits a wide variety of spatiotemporal patterns of neuronal activity recorded using functional magnetic resonance imaging as the so-called blood-oxygenated-level–dependent (BOLD) signal. An active area of ...

ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contribut...

Abstract Objective The study aimed to evaluate the hypoxia-induced brain injury and neuroprotective effects of pyrimidine and its derivative, arylvinylpyrimidine (AVP), in the freshwater catfish, Heteropneustes fossilis....

Abstract Background Tauopathies are a group of neurodegenerative diseases, including Alzheimer’s disease (AD), characterized by progressive accumulation of pathological Tau proteins. Among the diverse Tau species, trun...

Abstract Mild traumatic brain injury (mTBI) disproportionately affects children and adolescents and has been associated with poorer neurocognitive performance, but the biological mechanisms driving symptom variability an...

Abstract Carbon nanotubes (CNTs) are promising nanomaterials with applications in biomedicine, including drug delivery and biosensing, due to their stability, biocompatibility, and ease of surface modification. However, ...

Electroencephalography (EEG) is a crucial technique for interpreting neurocognitive functions and the underlying neural information. Despite its advantages, such as high portability, cost-effectiveness and exceptional te...

Alcohol consumption, in particular ethanol (EtOH), typically begins in human adolescence, often in a “binge like” manner. However, although EtOH abuse has a high prevalence at this stage, the effects of exposure duri...

The effects of cannabinoids in mitochondria after acute oxidative stress insult are not fully established. We investigated the ability of CP55,940 and JWH-015 to scavenge reactive oxygen species and their effect on mitoc...