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Introduction: Malingering, the intentional fabrication or exaggeration of symptoms for external gain, remains a significant challenge in forensic psychiatry. Psychiatric illnesses are particularly vulnerable to malingeri...

Abstract Background Heartworms, a cause of pulmonary hypertension (PH) in dogs, can migrate from the pulmonary arteries into the heart resulting in life‐threatening caval syndrome (CS). Objectives To describe clinical ...

Background and purpose: Deviations in radiotherapy quality can significantly affect clinical trial outcomes, including overall survival. Radiotherapy quality assurance (RTQA) is a systematic process by which a RT plan is...

Background: This study aims to evaluate the effectiveness and efficiency of combined multiple-case teaching (MCT) and narrative medicine teaching (NMT) method compared with lecture-based learning (LBL) in the clinical pr...

Abstract Background and Objectives pediatric Cardiopulmonary resuscitation (CPR) is critical for saving children who experience cardiac arrest, but traditional teaching is often ineffective at improving clinical competen...

Mucopolysaccharidosis type II (MPS II) is an X-linked recessive lysosomal storage metabolic disorder caused by pathogenic mutations in the iduronate-2-sulfatase (IDS) gene. Herein, we report the case of a 2-year-old male...

Multiple Primary Cancers (MPCs), especially synchronous combined hepatocellular-cholangiocarcinoma (cHCC-CCA) complicated with gallbladder adenocarcinoma, are extremely rare clinically. This case report discusses a 73-ye...

Abstract Background Regulatory barriers present significant challenges to clinical trial approval during both “peacetime” and pandemics, particularly for multi-country clinical trials sponsored by academic institutio...

Abstract Background Bordetella pertussis (BP) infection has risen rapidly in pediatrics recently, and next-generation sequencing has significantly improved pertussis’ early diagnosis. High detection rates raise the con...

Abstract Background Guidelines‐driven screening protocols for early cancer detection in dogs are lacking, and cancer often is detected at advanced stages. Hypothesis/Objectives To examine how cancer typically is detect...

Abstract Circumaortic left renal vein (CLRV) is a rare variation in which two renal veins encircle the aorta prior to draining into the inferior vena cava (IVC) and can be classified into three types based on branching p...

Abstract Objective: Cushing’s syndrome, characterized by chronic hypercortisolism, is associated with various health risks, including psychiatric symptoms and cognitive impairments. This systematic review of case stud...

BackgroundRare epidermal growth factor receptor (EGFR) mutations have a low incidence, and their response to EGFR tyrosine kinase inhibitors (TKI) has not been sufficiently studied. L747P is a rare EGFR mutation located ...

Abstract Background Serum beta-human chorionic gonadotropin is routinely measured as a pregnancy marker in women of reproductive age prior to diagnostic and therapeutic interventions. Although a positive result commonly ...

BackgroundPulmonary Epstein–Barr virus-associated smooth muscle tumor (EBV-SMT) is extremely rare in children with congenital immunodeficiency. This case report describes the clinical details of a pediatric pulmonary E...

ABSTRACT Background Equine gastric ulcer syndrome (EGUS) adversely affects the health, welfare, and performance of sports horses, requiring gastroscopy for definitive diagnosis. Owners frequently consider girth aversion...

IntroductionLarge language models (LLMs) may support clinical reasoning, yet real-world outpatient studies integrating structured clinical data with chest radiographs (CXRs) remain limited. We compared three LLMs for pul...

BackgroundParathyroid carcinoma (PC) is a rare and often misdiagnosed endocrine malignancy that can present with diverse clinical manifestations, complicating its detection and management.Case presentationThis case repor...

Abstract Background Appendiceal mucinous adenocarcinoma (AMA) is exceptionally rare, constituting less than 0.5% of all gastrointestinal malignancies and demonstrating an annual incidence of only 1 to 2 cases per million...

Background: Thyroid cancer is one of the most prevalent endocrine neoplasms in Brazil, and radioiodine therapy (RAI) is a well-established adjuvant treatment. However, managing RAI can be particularly challenging in pati...

Abstract The early diagnosis of leprosy remains challenging in low-endemic regions. However, the implementation of clinical pathways (CPs) to improve diagnostic accuracy and understand patterns of misdiagnosis and delaye...

Abstract Background Small cell carcinoma is a highly aggressive neuroendocrine malignancy that most commonly arises in the lungs, gastrointestinal tract, or pancreas. Primary small cell neuroendocrine carcinoma of the en...

ObjectiveThis study aimed to investigate the prognostic factors of endoscopic submucosal dissection (ESD) in early colorectal cancer patients and to develop a predictive model for assessing prognostic risk.MethodsWe retr...

ABSTRACT: The integration of AI in dental practice, primarily through AI-enabled software, influences clinical workflows by promoting rapid decision-making and potentially increasing bias stemming from its automation bia...