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100 resultados encontrados.

Tipos de recurso: Libro electrónico Artículo Revista Tesis Capítulo
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Unraveling novel therapeutic targets for diffuse large B-cell lymphoma: a plasma multi-omics study
Artículo
Acceso abierto Artículo DOAJ
Xu Sun et al · Frontiers Media S.A · 2026 · ISSN 1663-9812
BackgroundDiffuse large B-cell lymphoma (DLBCL), the most common non-Hodgkin lymphoma, exhibits genetic heterogeneity and variable treatment responses. Discovering new therapeutic targets is critical to improve outcomes....
LCC LCC:Therapeutics. PharmacologyIdioma eng
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Open Access
Analysis of the status of perceived professional benefits among nursing students and their relationship with teaching behaviors among nursing teachers
Artículo
Acceso abierto Artículo DOAJ
Peilan Xu et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
BackgroundClinical internship is a critical stage for shaping nursing students’ professional attitudes and identity. Perceived professional benefit during internship is associated with career satisfaction and retention...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Open Access
Global research trends at the intersection of climate change and parasitic diseases: a systematic bibliometric research (2000–2025)
Artículo
Acceso abierto Artículo DOAJ
Nuermaimaiti Maireyamuguli et al · Frontiers Media S.A · 2026 · ISSN 2235-2988
BackgroundClimate change is increasingly recognized as a critical driver affecting the transmission and distribution of parasitic diseases. However, a comprehensive synthesis of the global research landscape in this inte...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Open Access
Sex as a biological variable in amblyopia: implications for developmental plasticity and treatment
Artículo
Acceso abierto Artículo DOAJ
Kathryn M. Murphy et al · Frontiers Media S.A · 2026 · ISSN 1662-453X
Amblyopia is a common childhood visual disorder caused by abnormal visual experience that drives visual cortical plasticity during the sensitive period. The timing and forms of treatment with patching therapy and other t...
LCC LCC:Neurosciences. Biological psychiatry. NeuropsychiatryIdioma eng
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Open Access
The adaptation of scientific reasoning of prospective teachers for primary education in the perspective of civic science
Artículo
Acceso abierto Artículo DOAJ
Yayuk Hidayah et al · Universitas Negeri Yogyakarta · 2021 · ISSN 1829-5789
This article aims to determine the adaptation of prospective elementary school teachers' scientific reasoning from a civic science perspective through seminar courses on elementary schools' educational problems. The issu...
LCC TENDOkVkdWNhdGlvbiAoR2VuZXJhbCk~Idioma eng
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Open Access
A Review of Perceived Risk Role in Autonomous Vehicles Acceptance
Artículo
Acceso abierto Artículo DOAJ
Jen Sim Ho et al · MMU Press · 2023 · ISSN 2735-1009
The purpose of this study is to critically review literature pertaining to the theoretical concept of perceived risk and its role in autonomous vehicle (AV) studies. A mapping on the placement of perceived risk to explai...
LCC TENDOlNvY2lhbCBTY2llbmNlcw~~Idioma eng
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Open Access
A sociologia da literatura de Lucien Goldmann
Artículo
Acceso abierto Artículo DOAJ
Celso Frederico · Universidade de São Paulo · 2005 · ISSN 0103-4014
OS ESTUDOS literários de Lucien Goldmann conheceram duas fases distintas. Na primeira, apoiando-se principalmente nas contribuições do jovem Lukács (A alma e as formas e Teoria do romance), Goldmann buscou estabelece...
LCC TENDOlNvY2lhbCBzY2llbmNlcyAoR2VuZXJhbCk~Idioma eng
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Open Access
AI in Point-of-Care Imaging for Clinical Decision Support: Systematic Review of Diagnostic Accuracy, Task-Shifting, and Explainability
Artículo
Material complementario disponible Artículo DOAJ
Peter Wadie et al · JMIR Publications · 2026 · ISSN 2817-1705
Abstract BackgroundArtificial intelligence (AI) integrated with point-of-care imaging is a promising approach to expand access in settings with limited specialist availability. However, no systematic review h...
LCC TENDOkNvbXB1dGVyIGFwcGxpY2F0aW9ucyB0byBtZWRpY2luZS4gTWVkaWNhbCBpbmZvcm1hdGljcw~~Idioma eng
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Access to essential medicines for diabetes care: availability, price, and affordability in central Ethiopia
Artículo
Acceso abierto Artículo DOAJ
Hachalu Dugasa Deressa et al · KeAi Communications Co., Ltd · 2024 · ISSN 2397-0642
Abstract Background Diabetes is a major global public health burden. Effective diabetes management is highly dependent on the availability of affordable and quality-assured essential medicines (EMs) which is a challenge ...
LCC LCC:Public aspects of medicineIdioma eng
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Open Access
Appraising the role of alleviating financial constraints and knowledge sharing in advancing technological innovation environment
Artículo
Acceso abierto Artículo DOAJ
Hayford Asare Obeng et al · SpringerOpen · 2026 · ISSN 2192-5372
Abstract Technological innovations have become more necessary in the post-COVID-19 economic recovery strategies. Although financial literacy, particularly among CEOs, influences firms’ performance, the existing studies...
LCC LCC:Business; TENDOkNvbW1lcmNpYWwgZ2VvZ3JhcGh5LiBFY29ub21pYyBnZW9ncmFwaHk~Idioma eng
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Open Access
Cultivating demand: A systematic literature review on agroecology's role in consumer behavior
Artículo
Material complementario disponible Artículo DOAJ
Christina Kleisiari et al · Elsevier · 2026 · ISSN 2666-7843
This paper presents a systematic literature review that synthesizes existing empirical research on consumer behavior toward sustainable and agroecological food products. Following the PRISMA guidelines, the review examin...
LCC TENDOkVudmlyb25tZW50YWwgZWZmZWN0cyBvZiBpbmR1c3RyaWVzIGFuZCBwbGFudHM~; LCC:Economic growth, development, planningIdioma eng
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Determining the Risk of Developing Severe Sepsis Using Genetic Profiling of Innate Immunity Genes
Artículo
Acceso abierto Artículo DOAJ
E.A. Polyakova et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Background and AimsThe immune response to an infectious agent is regulated by a complex network of signaling pathways involving numerous genes encoding inflammatory mediators, proteins of the innate and adaptive immune s...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Open Access
Enhancing Cyber Hygiene among Communities through Experiential Cyber-Security Awareness Programs
Artículo
Material complementario disponible Artículo DOAJ
Dr Atul Bamrara et al · Kennesaw State University · 2026 · ISSN 2472-2707
Human error remains the most frequently exploited vulnerability in the cyber-security ecosystem. Despite substantial investments in technical safeguards, cybercriminals increasingly rely on social engineering, misinforma...
LCC TENDOlNwZWNpYWwgYXNwZWN0cyBvZiBlZHVjYXRpb24~Idioma eng
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Evidence and gap map report: Social and Behavior Change Communication (SBCC) interventions for strengthening HIV prevention and research among adolescent girls and young women (AGYW) in low‐ and middle‐income countries (LMICs)
Artículo
Material complementario disponible Artículo DOAJ
Devi Leena Bose et al · SAGE Publishing · 2023 · ISSN 1891-1803
Abstract Background Adolescent girls and young women (AGYW), aged 15–24 years, are disproportionately affected by HIV and other sexual and reproductive health (SRH) risks due to varying social, cultural, and economic f...
LCC TENDOlNvY2lhbCBTY2llbmNlcw~~Idioma eng
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Exploring the influence of locality on stakeholder behavioral intentions in industrial heritage tourism from a sense of place perspective
Artículo
Acceso abierto Artículo DOAJ
HongXia Chen et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract This study advances the Cognitive-Affective-Conative (CAC) model by conceptualizing a novel framework that integrates stakeholders’ local perception, sense of place, and behavioral intentions in industrial her...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Open Access
GUEST EDITORS’ NOTE
Artículo
Material complementario disponible Artículo DOAJ
Asmir Gračanin et al · University of Rijeka · 2026 · ISSN 1332-0742
Throughout history, our capacity to shed tears has attracted the attention of poets, writers, philosophers, and scholars. Moreover, humans' fascination with tears is evident in the significant roles they played in legend...
LCC TENDOlBzeWNob2xvZ3k~Idioma eng
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Generative AI and student collaboration: a scoping review of group work processes, outcomes, and risks
Artículo
Material complementario disponible Artículo DOAJ
Yan Wei et al · BMC · 2026 · ISSN 1833-2595
Abstract Generative artificial intelligence is increasingly used by higher education students during group work; however, evidence on how it reshapes collaboration remains fragmented. This scoping review maps recent rese...
LCC LCC:Theory and practice of educationIdioma eng
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Gut microbiota–intestinal barrier crosstalk: mechanistic advances, disease relevance, and public health implications
Artículo
Material complementario disponible Artículo DOAJ
Changmei Chen et al · Frontiers Media S.A · 2026 · ISSN 2296-2565
BackgroundThe intestinal barrier is a critical interface between the host and the external environment, and growing evidence indicates that bidirectional crosstalk between the gut microbiota and the intestinal barrier is...
LCC LCC:Public aspects of medicineIdioma eng
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Histone Methyltransferase EZH2 Induces Akt-Dependent Genomic Instability and BRCA1 Inhibition in Breast Cancer
Artículo
Acceso abierto Artículo CONICET Digital
Gonzalez, Maria E. et al · American Association for Cancer Research · 2011 · ISSN 2360-2370
Increased levels of EZH2, a critical regulator of cellular memory, signal the presence of metastasis and poor outcome in breast cancer patients. High levels of EZH2 are associated with nuclear pleomorphism, lack of estro...
Idioma eng
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Open Access
Human FOXP3 Isoforms in Health and Disease
Artículo
Acceso abierto Artículo DOAJ
Merve Nida Gokbak et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Forkhead box P3 (FOXP3) is the master transcription factor of regulatory T cells (Tregs) and is essential for maintaining immune tolerance. FOXP3 is stably expressed in Tregs, driving their suppressive function, and it i...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Open Access
Identification of MBT3T as a new effective therapeutic option in imatinib-resistant gastrointestinal stromal tumors (GISTs)
Artículo
Acceso abierto Artículo DOAJ
Gloria Ravegnini et al · BMC · 2026 · ISSN 1756-9966
Abstract Background Gastrointestinal stromal tumors (GISTs) are primarily treated with tyrosine kinase inhibitors (TKIs) such as imatinib. However, the development of drug resistance remains a critical clinical challenge...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Open Access
Indole-3-Carbaldehyde from Limosilactobacillus reuteri Boosts Chemotherapy Response in Diffuse Large B Cell Lymphoma by Blocking the Mechanistic Target of Rapamycin Pathway
Artículo
Acceso abierto Artículo DOAJ
Zhengfeng Zhang et al · American Association for the Advancement of Science (AAAS) · 2026 · ISSN 2639-5274
Diffuse large B cell lymphoma (DLBCL) presents a critical clinical challenge due to declining chemosensitivity and difficult-to-manage dose-limiting toxicities. Although gut microbiota modulation shows potential for “t...
LCC TENDOlNjaWVuY2U~Idioma eng
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Open Access
Learning From Loss: Early Identification of ADA-SCID After Sibling Mortality
Artículo
Material complementario disponible Artículo DOAJ
Amal Farooq et al · Rockefeller University Press · 2026 · ISSN 3065-8993
IntroductionAdenosine deaminase–deficient severe combined immunodeficiency (ADA-SCID) is an autosomal recessive disorder comprising ∼15% of SCID cases. Newborn screening (NBS) relies on T cell receptor excision circl...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Next-Generation SCS Programming Platform: Enhancing ECAP Fidelity and Objectivity to Improve Patient Experience
Artículo
Material complementario disponible Artículo DOAJ
Daniel J. Parker et al · Adis, Springer Healthcare · 2026 · ISSN 2193-8237
Abstract Introduction Evoked compound action potentials (ECAPs) are neurophysiological biomarkers of neural activation during spinal cord stimulation (SCS). Clear distinction between ECAPs and nonphysiological signals is...
LCC LCC:AnesthesiologyIdioma eng
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