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Abstract Background HIV/AIDS continues to pose a significant public health challenge globally and in India, despite the availability of free antiretroviral therapy (ART) through government healthcare services. People liv...

En este trabajo indagamos el íntimo lazo entre capitalismo, sensibilidad y violencia. Para esto abordamos algunas reflexiones de la pensadora mexicana Sayak Valencia quien ha propuesto el adjetivo gore para caracterizar...

Abstract Cisplatin (CISP) is a platinum-based chemotherapeutic drugs that are commonly used to treat several types of cancers. However, its clinical application faces several hurdles that could limit its clinical efficie...

The new Food and Drug Administration (FDA) announcement makes it even more necessary to find alternatives to trans fats. The effect of cooling rate and temperature cycles on crystallization behavior and polymorphism of t...

Abstract Background Previous studies have evaluated traditional Chinese medicine (TCM) clinical randomized controlled trial (RCT) literature broadly, but they have provided limited depth in evaluating the specific aspect...

Aim: The objective of our study was to formulate a nanoparticulate drug delivery system that provides controlled delivery of ibuprofen directly targeting colon leading to optimized dosage, reduced side effects ultimately...

Objective: Development & Optimization of Ofloxacin Floating tablets to enhance gastric retention time. Sustained release effect of formulation will reduce the dosing frequency for UTIs and prolonged local effect will ben...

This research paper aims to study how poor mental and physical health could impact the productivity of employees.  A person's overall health is of utmost importance as it has a serious contribution towards contentment i...

Central obesity is characterized by visceral adipose tissue (VAT) expansion, considered one of the main risk factors for metabolic complications. In recent years, new drugs have been studied for obesity treatment. Liragl...

This study tries to elucidate the mechanisms by which fructose rich diets (FRD) inhibit the rat intestinal Ca2+ absorption, and determine if any or all underlying alterations are prevented by naringin (NAR). Male rats we...

Abstract Primary endothelial cells (e.g., HUVEC) are essential in basic research and drug development, yet contradictory or poorly reproducible experimental results are common in the literature. We investigated whether s...

Od swojego zarania przedmieście Święty Wojciech, położone na północ od miejskich murów, w widłach dwóch niewielkich cieków – Rudnika (Bogdanki) i Wierzbaka, lewobrzeżnych dopływów Warty, pełniło niezmie...

Ethosomes, a lipid-based vesicular system, are a cutting-edge method for delivering medicinal drugs transdermally for either local or systemic action. Betamethasone Dipropionate ethosomes were fabricated and then these w...

Over the past few decades, the pharmaceutical sector has witnessed the occurrence of a particular type of agreement used to settle patent disputes between originator and generic drug manufacturers: so-called reverse paym...

DrugBank (www.drugbank.ca) is a web-enabled database containing comprehensive molecular information about drugs, their mechanisms, their interactions and their targets. First described in 2006, DrugBank has continued to ...

Multielement analysis of crude drug and infusions from Achyrocline satureioides and A. tomentosa (Asteraceae), "marcelas", were carried out by ICP-OES, to know both mineral composition and safety. These plants are used a...

A new reversible thermosensitive drug delivery system was designed and prepared by using chitosan and glycerophosphate with or without poly (ethylene glycol) and used as an a carrier for the Miconazole nitrate, an antifu...

The estimation of the probability that a drug caused an adverse clinical event is usually based on clinical judgment. Lack of a method for establishing causality generates large between-raters and within-raters variabili...

The aim of the present investigation is to improve the dissolution of poorly water soluble drug valsartan by preparing solid dispersions and also to evaluate the effect of different inert carriers on flow properties of s...

The objective of the present study was to develop and evaluate a pulsatile system of theophylline based on chronopharmaceutical considerations. The basic design consists of an impermeable capsule body, which contains the...

The present study was undertaken to investigate the effect of nature of polymers like HPMC, carbopol-934P and their content levels on the release profiles of water soluble drug, diclofenac potassium. For this purpose, di...

KEGG (http://www.kegg.jp/ or http://www.genome.jp/kegg/) is an encyclopedia of genes and genomes. Assigning functional meanings to genes and genomes both at the molecular and higher levels is the primary objective of the...

We have developed a rapid, sensitive, and inexpensive method for measuring the cellular protein content of adherent and suspension cultures in 96-well microtiter plates. The method is suitable for ordinary laboratory pur...