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The increasing prevalence of artificial light sources has rendered blue light (BL) a novel environmental metabolic disruptor. This study aimed to investigate the potential effects of BL exposure on mitochondrial function...

Chlorfenapyr (CHL) is a widely used insecticide whose expanding application raises concerns about cardiotoxicity following both acute poisoning and chronic environmental exposure. The mechanisms underlying its cardiac in...

Evidence links pesticides to nonalcoholic fatty liver disease (NAFLD), but the combined effects of dietary pesticide residue mixture exposure on NAFLD remain poorly documented. This study employed a 42-day subchronic exp...

The current number of emerging contaminants worldwide may reach tens of thousands. However, research on the extra-pulmonary toxicity induced by combined exposure of extremely low-dose emerging pollutants remains extremel...

Biostimulation and bioaugmentation are promising for remediating acid in-situ leaching (AISL) U mine groundwater, yet their efficiencies, mechanisms, and acid stress regulation remain unclear. This study collected ground...

Triclosan (TCS) is widely applied to daily necessities as a chemical bacteriostatic agent. Environmental TCS levels have increased significantly following the coronavirus disease 2019 pandemic, posing a potential threat ...

Given the widespread application of copper oxide nanoparticles (CuONPs), their biosafety has attracted significant attention. However their effects on the developmental capacity of mammalian preimplantation embryos and t...

Di-(2-ethylhexyl) phthalate (DEHP) is a ubiquitous environmental endocrine disruptor that leaches from polyvinyl chloride products and metabolizes to mono-(2-ethylhexyl) phthalate (MEHP), causing spermatogenic dysfunctio...

Glyphosate (GLY) is the most widely used herbicide worldwide. However, in organic and conventional farming systems, a natural alternative — nonanoic (pelargonic) acid (PA) — is gaining importance. PA is a non-selecti...

Cadmium (Cd) accumulation in rice poses a serious threat to food safety. While soil amendments with manganese (Mn) and zinc (Zn) can reduce Cd accumulation in rice, their distinct modes of action remain unclear, hinderin...

Moxidectin (MOX) belongs to the macrocyclic lactones, a class of anthelmintic drugs widely used in livestock that can enter the soil environment and persist by binding to soil organic matter. While MOX is effective again...

Bisphenol A (BPA) can combine with glycidyl methacrylate to form bisphenol A glycidyl methacrylate (Bis-GMA). Bis-GMA is an important industrial raw material and a significant component of dental resin materials. Althoug...

The widespread application of chlorantraniliprole (CAP) in rice-crayfish co-culture systems poses a potential threat to the health of the non-target crustacean Procambarus clarkii. However, the sub-chronic effects of env...

Phthalate plasticizers, especially diethyl phthalate (DEP), are linked to metabolic disorders, while their precise role and mechanism in diabetic nephropathy (DN) pathogenesis remain unclear. Here, we integrated transcri...

Glyphosate-based herbicides (GBH) are the most widely used herbicides worldwide. Epidemiological studies have suggested that maternal exposure to GBH is associated with reduced fertility and shortened gestational length....

Cured-in-place pipe (CIPP) technology is widely used for pipeline rehabilitation, but curing emissions and leachates may introduce complex chemical mixtures into air and drinking water, raising environmental health conce...

Limited studies focused on acute effects of PM2.5 components and sources exposure on blood pressure and the potential mediating role of DNA methylation. We conducted a repeated-measurement study design with 4 visits invo...

Modern lifestyle factors, including dietary choices, significantly affect individual and intergenerational health. The widespread reliance on processed and takeout foods, along with the regular use of cosmetics and perso...

Tetrachlorobisphenol A (TCBPA), a widely used chemical on material modification and flame retardant synthesis, bioaccumulates through the food chain and presents significant health concerns. However, the long-term effect...

Surface functionalization of cellulose nanocrystals (CNCs) is commonly used to improve their dispersibility, functionality, and performance across diverse applications. However, the potential biosafety risks of these mod...

Bronchoalveolar lavage fluid (BALF) analysis provides critical insights into pulmonary inflammation by identifying cellular components and inflammatory mediators in the airways and alveoli. However, variations in BALF co...

Microplastics (MPs), environmental pollutants resulting from the degradation of plastic products and industrial processes, have become ubiquitous in global ecosystems. MPs can enter the human body through ingestion, inha...

The kidney is a primary organ of heavy metal accumulation, and metal toxicity poses a great challenge to kidney health. We conducted a repeated-measure study to examine the longitudinal associations between blood heavy m...