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Introduction and aims: Skeletal Class II malocclusion is heterogeneous, and conventional two-dimensional cephalometry may not fully capture relevant three-dimensional (3D) craniofacial variation. This study aimed to iden...

BackgroundThe growing global population of older adults presents significant challenges for health and social care systems, requiring effective quality improvement (QI) interventions to enhance care delivery and outcomes...

Introduction: Extended reality (XR), an umbrella term encompassing virtual reality, augmented reality, and mixed reality, is increasingly being explored to address educational, procedural, and psychosocial challenges in ...

Background The general practitioners’ (GP) workforce is in crisis, with 22% of GPs feeling so stressed by the pressures of general practice they cannot cope. Patient death is the greatest stressor in medical practice a...

Abstract Background Wilson disease (WD) is a rare inherited copper metabolism disorder with variable prevalence worldwide. Many regions lack reliable data, leading to underestimation of burden. WD presents with hepatic, ...

ABSTRACT Objectives This scoping review aims to systematically explore the existing literature on golf‐related injuries in adolescent golfers aged 10–19 years, focusing on injury prevalence, management strategies, an...

BackgroundThe intestinal barrier is a critical interface between the host and the external environment, and growing evidence indicates that bidirectional crosstalk between the gut microbiota and the intestinal barrier is...

Abstract Background The ageing and growing population, rising cancer rate, and increased healthcare demand drive higher medical costs. Integrating Artificial Intelligence (AI) into oncology revolutionizes cancer diagnosi...

Clinical research and real-world observational studies are essential for advancing the diagnosis and treatment of rare diseases, such as inborn errors of immunity/primary immune disorders (IEI/PID). To support efficient ...

Abstract Human papillomavirus (HPV) vaccination is a safe and cost-effective strategy for preventing cervical cancer, yet uptake remains low worldwide, particularly in low- and middle-income countries (LMICs). Numerous i...

Aims: Acute hand and wrist infections can be devastating, with a substantial burden in low- and middle-income countries (LMICs) compared with high-income countries. Access to treatment, particularly surgery, can be limit...

Abstract Background Surgeons work in high-pressure, high-risk environments, which can lead to physical and mental health challenges. Physical activity (PA) has known benefits for health, stress reduction, and professiona...

Abstract Background Climate change is increasingly influencing the prevalence and severity of various diseases. While previous studies have linked climate variables to emergency department (ED) admissions, few have exami...

Background Benzoxaboroles showed significant antimicrobial efficacy in the past, warranting further investigation.Research design and methods Benzoxaboroles were evaluated for their cytotoxicity on Vero E6 and PBMCs, as ...

Abstract Background: Marker-based training is a widely used type of positive reinforcement training believed to improve learning outcomes by providing a precise and consistent marker for desired behavior. However, resear...

Abstract Objective To review and analyze existing literature on palliative care in rural, remote, and Northern communities and consider the gaps that remain in research in order to guide the direction of the current proj...

Abstract Background Chronic conditions cause millions of deaths annually worldwide. Remote patient monitoring using wearable devices and sensors, combined with machine learning (ML), offers promising strategies for disea...

While traditional Project-based Learning (PjBL) enhances engagement, creativity, and conceptual understanding, emerging socioformative approaches are pedagogies that highlight the need for interdisciplinary, ethically gr...

Abstract Background Social mixing studies provide crucial evidence for parameterizing mathematical models of infectious disease transmission, and their validity for use in models is dependent on their study design and ho...

Abstract Background Silicosis is an irreversible scarring lung disease caused by occupational respirable crystalline silica (RCS) dust exposure. Mineral (noncoal) miners who extract metal, nonmetal, stone, and sand/grave...

Background: The release of micro- and nanoplastics (MNPs) from tea bags during brewing is a significant, recently identified source of potential human exposure. This systematic review collected global research published ...

Abstract Background Microglial activation is increasingly recognized as a critical contributor to both the initiation and chronification of migraine. Recent advances have highlighted the importance of receptor-mediated s...

BackgroundThe use of augmented reality (AR) and virtual reality (VR) to address addictive behaviors such as substance use disorders and gambling disorders has been growing. However, little has been done to explore the us...