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Comprehensive analysis of RNA sequencing reveals DNA damage response and immune-associated alternative splicing and RBP regulators contributing to preeclampsia
Artículo
Acceso abierto Artículo DOAJ
Comprehensive analysis of RNA sequencing reveals DNA damage response and immune-associated alternative splicing and RBP regulators contributing to preeclampsia
YanHua Wang et al · BMC · 2026 · ISSN 1471-2164
Abstract Background Preeclampsia (PE), a life-threatening hypertensive disorder of pregnancy, remains poorly characterized at the post-transcriptional regulation level. While alternative splicing (AS) perturbations drive...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:GeneticsIdioma eng
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Contamination investigation and pathogenic characteristics analysis of Burkholderia gladioli pv. cocovenenans
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Contamination investigation and pathogenic characteristics analysis of Burkholderia gladioli pv. cocovenenans
YANG Hui et al · The Editorial Office of Chinese Journal of Food Hygiene · 2025 · ISSN 1004-8456
ObjectiveTo investigate the contamination levels of foods such as woodear， Tremella fuciformis （white jelly fungus）， and rice noodles caused by Burkholderia gladioli pv. cocovenenans， and to elucidate the patho...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Nutrition. Foods and food supplyIdioma zho
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Discovering novel driver mutations from pan-cancer analysis of mutational and gene expression profiles.
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Discovering novel driver mutations from pan-cancer analysis of mutational and gene expression profiles.
Houriiyah Tegally et al · Public Library of Science (PLoS) · 2020 · ISSN 1932-6203
As the genomic profile across cancers varies from person to person, patient prognosis and treatment may differ based on the mutational signature of each tumour. Thus, it is critical to understand genomic drivers of cance...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Evolutionary dynamics of HIV-1 recombinants: analysis of contemporary and historical viral populations in East Africa
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Evolutionary dynamics of HIV-1 recombinants: analysis of contemporary and historical viral populations in East Africa
Sheila N. Balinda et al · BMC · 2026 · ISSN 1743-422X
Abstract Background Understanding the genetic evolution of HIV-1 Transmitted/Founder (T/F) virus is crucial for developing effective treatment and prevention strategies due to its rapid mutation and recombination rates. ...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Genetic analysis of biopsy-related droplets in patients undergoing PGT-A and its potential application
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Genetic analysis of biopsy-related droplets in patients undergoing PGT-A and its potential application
Zhiqing Huang et al · Frontiers Media S.A · 2026 · ISSN 1664-2392
PurposePreimplantation genetic testing for aneuploidy (PGT-A) is essential for selecting embryos free from chromosomal abnormalities before transfer. However, challenges such as detection failures, mosaicism, and the lim...
LCC LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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Genetics of B Cell Maturation in Common Variable Immunodeficiency in Brazil: A Joint Analysis of the CVID-Brazil Cohort and the CNE3I Program
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Genetics of B Cell Maturation in Common Variable Immunodeficiency in Brazil: A Joint Analysis of the CVID-Brazil Cohort and the CNE3I Program
Beatriz Costa Todt et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency and remains underdiagnosed in Brazil due to limited knowledge of its genetic landscape. Since 2024, the Centro Nacional d...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Genotype characterization of the Haematobia Irritans (diptera: muscidae) from Brazil, Dominican Republic and Colombia based on randomly amplified polymorphic dna (rapd) analysis Caracterização genotípica de Haematobia irritans (Diptera: Muscidae) procedentes do Brasil, República Dominicana e Colômbia baseada na análise do DNA polimórfico amplificado ao acaso (RAPD)
Artículo
Material complementario disponible Artículo DOAJ
Genotype characterization of the Haematobia Irritans (diptera: muscidae) from Brazil, Dominican Republic and Colombia based on randomly amplified polymorphic dna (rapd) analysis Caracterização genotípica de Haematobia irritans (Diptera: Muscidae) procedentes do Brasil, República Dominicana e Colômbia baseada na análise do DNA polimórfico amplificado ao acaso (RAPD)
Luciana Gatto Brito et al · Colégio Brasileiro de Parasitologia Veterinária · 2008 · ISSN 0103-846X
Blood-sucking flies are important parasites in animal production systems, especially regarding confinement conditions. Haematobia irritans, the horn fly, is one of the most troublesome species within bovine production sy...
LCC LCC:Animal cultureIdioma eng
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How dynamic could be the 45S rDNA cistron? An intriguing variability in a grasshopper species revealed by integration of chromosomal and genomic data
Artículo
Acceso abierto Artículo CONICET Digital
How dynamic could be the 45S rDNA cistron? An intriguing variability in a grasshopper species revealed by integration of chromosomal and genomic data
Ferretti, Ana B. S. M. et al · Springer Verlag Berlín · 2019 · ISSN 0009-5915
To better understand the structure and variability of the 45S rDNA cistron and its evolutionary dynamics in grasshoppers, we performed a detailed analysis combining classical and molecular cytogenetic data with whole-gen...
Idioma eng
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Integrative machine learning analysis suggests novel molecular targets for liver cancer diagnosis and therapy
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Integrative machine learning analysis suggests novel molecular targets for liver cancer diagnosis and therapy
Fengrui Zhou et al · Springer · 2026 · ISSN 2730-6011
Abstract Background Hepatocellular carcinoma (HCC) is a critical condition characterized by unchecked cellular growth in the liver, often leading to systemic inflammation and organ failure. Although its complex molecular...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Mixed infections and heteroresistance of Mycobacterium tuberculosis among multidrug-resistant tuberculosis in China: a genomic epidemiology study
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Mixed infections and heteroresistance of Mycobacterium tuberculosis among multidrug-resistant tuberculosis in China: a genomic epidemiology study
Yanping Liu et al · Taylor & Francis Group · 2025 · ISSN 2222-1751
Mixed infection refers to the presence of multiple Mycobacterium tuberculosis strains within one host, while heteroresistance denotes the coexistence of drug-susceptible and drug-resistant strains or genotypes. Mixed inf...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~; TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Pan-cancer analysis identifies JMJD6 as an oncogene and prognostic biomarker
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Pan-cancer analysis identifies JMJD6 as an oncogene and prognostic biomarker
Lihua Liu et al · Springer · 2026 · ISSN 2730-6011
Abstract JMJD6, a bifunctional epigenetic modulator within the Jumonji C family, has garnered increasing attention for its potential roles in tumorigenesis, yet its pan-cancer prognostic and mechanistic significance rema...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Whole-genome sequencing reveals genomic diversity and population structure of mango germplasm from the Jazan region of Saudi Arabia
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Whole-genome sequencing reveals genomic diversity and population structure of mango germplasm from the Jazan region of Saudi Arabia
Naser B. Almarri et al · Frontiers Media S.A · 2026 · ISSN 1664-462X
BackgroundMango (Mangifera indica L.) is an economically important tropical fruit crop, yet the genomic diversity of mango germplasm from the Jazan region of Saudi Arabia—the country's primary production hub—remains ...
LCC TENDOlBsYW50IGN1bHR1cmU~Idioma eng
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A regulatory network underlying glume hardness revealed by transcriptomic analysis of an ems-induced mutant in synthetic hexaploid wheat
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A regulatory network underlying glume hardness revealed by transcriptomic analysis of an ems-induced mutant in synthetic hexaploid wheat
Xin Liu et al · BMC · 2026 · ISSN 1471-2164
Abstract Background Tenacious glume a key trait limiting threshing efficiency in synthetic hexaploid wheat (SHW), represents an ancestral defense mechanism inherited from wild progenitors. Despite its evolutionary import...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:GeneticsIdioma eng
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Comparative analysis of mitochondrial genomes in the Ceratocystidaceae reveals highly conserved gene organization despite substantial genome size variation
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Comparative analysis of mitochondrial genomes in the Ceratocystidaceae reveals highly conserved gene organization despite substantial genome size variation
Anien Viljoen et al · BMC · 2026 · ISSN 1471-2164
Abstract Background Comparative studies of mitochondrial genomes can assist in determining evolutionary and phylogenetic relationships. In the Ceratocystidaceae fungal family, mitochondrial genomes from only two genera a...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:GeneticsIdioma eng
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Decoding clone evolution in HER2 amplified breast cancer through single-cell and spatial transcriptomics analysis of copy number variations
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Decoding clone evolution in HER2 amplified breast cancer through single-cell and spatial transcriptomics analysis of copy number variations
Jiao Yang et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract HER2-positive breast cancer exhibits marked genomic instability and heterogeneity, yet the clonal architecture and copy number variation (CNV) dynamics between ductal carcinoma in situ (DCIS) and invasive ductal...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Low GBX2 expression is associated with histological type B thymoma: a multi-omics analysis
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Low GBX2 expression is associated with histological type B thymoma: a multi-omics analysis
Zheng Lu et al · Springer · 2026 · ISSN 2730-6011
Abstract Objective To explore new diagnostic markers and therapeutic targets associated with the histological types of thymoma. Methods The TCGA and GEO was used to gather genomic and clinical data from thymoma patients....
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Proteomic analysis reveals the molecular mechanisms of deoxynivalenol-induced injury in the jejunum of piglets
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Proteomic analysis reveals the molecular mechanisms of deoxynivalenol-induced injury in the jejunum of piglets
Shuya Ma et al · BMC · 2026 · ISSN 1471-2164
Abstract Deoxynivalenol (DON), a prevalent Fusarium mycotoxin, poses a significant threat to intestinal health in piglets. This study established a deoxynivalenol (DON) intoxication model in piglets, revealing compromise...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:GeneticsIdioma eng
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Unraveling Tumor Heterogeneity: Quantitative Insights from Single-cell RNA Sequencing Analysis in Breast Cancer Subtypes
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Unraveling Tumor Heterogeneity: Quantitative Insights from Single-cell RNA Sequencing Analysis in Breast Cancer Subtypes
Senra, Daniela et al · Cognizant Communication Corp · 2025 · ISSN 1052-2166
Background and objectives: Tumors are complex systems characterized by variations across genetic, transcriptomic, phenotypic, and microenvironmental levels. This study introduced a novel framework for quantifying cancer ...
Idioma eng
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Candidate mutations used to aid the prediction of genetic merit for female reproductive traits in tropical beef cattle
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Candidate mutations used to aid the prediction of genetic merit for female reproductive traits in tropical beef cattle
Marina Rufino Salinas Fortes et al · Sociedade Brasileira de Zootecnia · 2018 · ISSN 1806-9290
ABSTRACT In this study, we aimed to provide a wet laboratory validation for a set of single nucleotide polymorphisms (SNP), which had been identified as candidate functional variants in silico. Genotyping for candidate S...
LCC LCC:Animal cultureIdioma eng
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Mitochondrial genomes of Terebelliformia: gene rearrangements, phylogenetic relationships, and evolutionary insights
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Mitochondrial genomes of Terebelliformia: gene rearrangements, phylogenetic relationships, and evolutionary insights
Xuelian Wei et al · BMC · 2026 · ISSN 1471-2164
Abstract Background An in-depth analysis was conducted on the mitochondrial genomes of three newly introduced Terebelliformia species (Amaeana sp., Terebellides sp.A and Terebellides sp.B), focusing on their genomic feat...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:GeneticsIdioma eng
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Phenocopies of 22q11.2DS: revealing genetic diversity in clinically suspected 22q11.2 deletion syndrome
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Phenocopies of 22q11.2DS: revealing genetic diversity in clinically suspected 22q11.2 deletion syndrome
Fanni Szumutku et al · SpringerOpen · 2026 · ISSN 2194-7791
Abstract Background Although 22q11.2 deletion syndrome (22q11.2DS) is one of the most common microdeletion syndromes, a substantial proportion of patients with clinically suspected 22q11.2DS (clin22q11.2) remain without ...
LCC TENDOlBlZGlhdHJpY3M~Idioma eng
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Prediction of non-genotoxic carcinogenicity based on genetic profiles of short term exposure assays
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Prediction of non-genotoxic carcinogenicity based on genetic profiles of short term exposure assays
Perez, Luis Orlando et al · Korean Society of Toxicology · 2016 · ISSN 1976-8257
Non-genotoxic carcinogens are substances that induce tumorigenesis by non-mutagenic mechanisms and long term rodent bioassays are required to identify them. Recent studies have shown that transcription profiling can be a...
Idioma eng
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Bioinformatics-driven insights: rapamycin-mediated CaMK2D inhibition alleviates intestinal ischemia-reperfusion injury
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Bioinformatics-driven insights: rapamycin-mediated CaMK2D inhibition alleviates intestinal ischemia-reperfusion injury
Ruxiang Sheng et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
IntroductionIntestinal ischemia-reperfusion (I/R) injury, a common and severe clinical condition with high morbidity and mortality, burdens healthcare systems. Our previous investigations established that a nano-delivery...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Genetic architecture of multiple myeloma: From somatic alterations to germline susceptibility and clinical implications
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Genetic architecture of multiple myeloma: From somatic alterations to germline susceptibility and clinical implications
María Carretero-Fernández et al · Elsevier · 2026 · ISSN 1936-5233
Multiple myeloma (MM) is best understood as a dynamically evolving genomic ecosystem shaped by inherited susceptibility, early oncogenic events, and continuous selective pressures. We propose an evolutionary genomics fra...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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