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Growth traits represent a main goal in aquaculture breeding programs and may be related to adaptive variation in wild fisheries. Integrating quantitative trait loci (QTL) mapping and next generation sequencing can greatl...

The accumulation of polyethylene (PE) mulch films in agricultural soils represents a persistent environmental challenge. This study aimed to construct and evaluate efficient microbial consortia for PE biodegradation and ...

Abstract Improving cacao yield, a key objective in post-domestication crop improvement, remains a primary goal for breeders, but progress is often hindered by the confounding effects of population structure. To overcome ...

Abstract Medicinal leeches are rich in various antithrombotic components, holding significant pharmaceutical value. To investigate the differences in potential antithrombotic capacity among species, this study utilized t...

BackgroundEuschistus heros and Piezodorus guildinii are major soybean pests across the Americas. Gut-associated bacteria influence insect nutrition, detoxification, and stress tolerance, potentially enhancing adaptation ...

Abstract The Leschenault’s rousette (Rousettus leschenaultii) represents a medium-sized bat of the genus Rousettus that feeds on fruits or flowers, mainly distributed in Southeast Asia. Here, we generated a chromosome-...

Abstract Background The prognosis and progression mechanisms of bladder cancer (BLCA) are highly heterogeneous, driven by complex genetic and epigenetic alterations. This study aimed to construct a robust prognostic sign...

Oral mucosal ageing represents a fundamental reprogramming of the tissue microenvironment, a dynamic process that underlies the functional decline and heightened disease susceptibility observed in the elderly. This revie...

ABSTRACT Cancer is driven by genomic lesions and malignancy‐promoting transcriptional programs. In blood cancers, both are often interconnected as lesions frequently affect transcription factor (TF)‐encoding genes. T...

Eukaryotic translation initiation factor 4E (eIF4E) is required for cap-dependent initiation. In addition, eIF4E occurs in cytoplasmic foci such as processing bodies (PB) and stress granules (SG). We examined the role of...

Plasmodiophora brassicae, the obligate parasite responsible for clubroot in Brassica crops and other crucifers, poses a major challenge to sustainable disease management due to its biotrophic lifestyle and adaptability. ...

Abstract Gymnodiptychus pachycheilus, a specialized schizothoracinae fish, exhibits remarkable morphological regression, such as near-complete scale loss, making it an important model for understanding the genomic basis ...

Stellaria Radix, known as Yinchaihu (YCH) in traditional Chinese medicine, is derived from the dried roots of Stellaria dichotoma L. var. lanceolata Bge. Despite its clinical importance in treating pediatric febrile cond...

Abstract The teak defoliator, Hyblaea puera, is a major pest damaging teak plantations and mangrove ecosystems. The high reproductive and dispersal capacities of this pest often lead to sudden and explosive outbreaks, po...

Abstract We present the complete genome sequence of Sphingomonas sp. gentR, a strain exhibiting high-level resistance to gentamicin (MIC = 40 mg/mL). The genome was assembled from hybrid Illumina and Nanopore seque...

Abstract Objective Streptococcus shenyangsis is a recently reported member of the genus Streptococcus, rarely detected in the human oral cavity and for which genomic information remains limited. To broaden our understand...

Abstract Background Preeclampsia (PE), a life-threatening hypertensive disorder of pregnancy, remains poorly characterized at the post-transcriptional regulation level. While alternative splicing (AS) perturbations drive...

Abstract Copper oxide nanoparticles (CuO-NPs) are known to trigger systemic toxicity through the disruption of copper homeostasis and the generation of profound oxidative stress. Given their widespread industrial applic...

This work describes a new method for extracting genomic DNA from heavy oil-contaminated soils. This method combines soil washes using three washing solutions with enzymatic lysis (SW-EL method). The suitability of the SW...

Abstract Modern poultry breeding requires integrated genomic and phenotypic data to optimize production traits, yet comprehensive resources remain fragmented and often inaccessible. We developed a comprehensive electroni...

Background: Mantle cell lymphoma (MCL) exhibits distinct biological characteristics and marked molecular heterogeneity, with TP53 mutations associated with particularly poor clinical outcomes. Eprenetapopt (APR-246), a f...

Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency and remains underdiagnosed in Brazil due to limited knowledge of its genetic landscape. Since 2024, the Centro Nacional d...

Abstract Digitalis purpurea (foxglove) is a widely distributed ornamental plant. Here, we present a long read sequencing-based genome sequence of a magenta flowering D. purpurea plant and a corresponding prediction of ge...

MicroRNAs (miRNAs), a class of small non-coding RNAs, are key regulators of gene expression at post-transcriptional level and play essential roles in biological processes such as development. MiRNAs silence target mRNAs ...