Buscar recursos académicos

Pregnancy is accompanied by complex physiological adaptations that influence hepatic metabolism, bile transport, coagulation, and immune tolerance, which may precipitate the development of pregnancy-specific liver disord...

BackgroundAsthma is traditionally conceptualized as a T helper 2 (Th2)-mediated inflammatory airway disease. However, increasing evidence suggests that primary immune dysregulation may underlie or phenotypically mimic as...

Abstract Introduction and objectives Perindopril-induced thrombocytopenia is a rare but potentially serious adverse drug reaction. It remains underrecognized in clinical practice, particularly in elderly patients with ca...

The rhizosphere is one of the most dynamic biological environments on Earth. Within this narrow zone surrounding plant roots, plants interact constantly with diverse communities of microorganisms including bacteria, fung...

Abstract Background Staphylococcus aureus skin infections represent a persistent clinical challenge owing to their high pathogenicity, multidrug resistance, and biofilm-associated recurrence, which collectively impair an...

Background and AimsSepsis is a common complication in patients with hematological malignancies that occurs during chemotherapy treatment, which in turn leads to acquired immunodeficiency. In recent years, increasing atte...

The innate immune response to West Nile virus (WNV) infection involves recognition through toll-like receptors (TLRs) and RIG-I-like receptors (RLRs), leading to establishment of an antiviral state. MiRNAs (miRNAs) have ...

IntroductionRituximab, an anti-CD40 antibody, is a commonly used B cell-depleting therapy. We present a case that illustrates the unveiling of an underlying common variable immune deficiency (CVID) after completion of ri...

Abstract Thrombocytopenia, defined as platelet count < 150,000mm3, is frequently diagnosed by obstetricians since this parameter is included in routine surveillance during pregnancy, with an incidence of between 7 and 12...

Materias / palabras clave: Biology; Innate immune system; Pattern recognition receptor; Immune system; Immune receptor; Autoimmunity; Receptor; Immunity; Immunology; Innate lymphoid cell; Acquired immune system; Pathogen-associated molecular patte...

Materias / palabras clave: Biology; Receptor; Pattern recognition receptor; Inflammation; Signal transduction; Cell biology; Immunology; Innate immune system; Autoimmunity; Nod; C-type lectin; Damp

Materias / palabras clave: Innate immune system; Pattern recognition receptor; Biology; Acquired immune system; Receptor; Immunology; Immune system; Immunity; Toll-like receptor; Pathogen-associated molecular pattern; Cell biology; Neuroscience

Tesis de Doctorado El bloqueo de los puntos de control como CTLA-4 y PD-1/PD-L1 ha demostrado la actividad de efectores inmunes antitumorales, por lo que ha aumentado el interés en el desarrollo de inmunoterapias contra...

Protein therapeutic agents frequently have short half-life in circulation due to their filtration by kidney, the action of proteolytic enzymes, the recognition by the immune system or the generation of neutralizing antib...

The hallmarks of cancer comprise six biological capabilities acquired during the multistep development of human tumors. The hallmarks constitute an organizing principle for rationalizing the complexities of neoplastic di...

Materias / palabras clave: immunology, immune recognition, immune response, endotoxins, innate immunity; Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy