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A Comparative Study Between Lipid A Extracted from Salmonella typhi and Pseudomonas Aeruginosa to Demonstrate the Extent of its Stimulation of Immune System

ISSN: 1812125X · Editor / fuente: University of Mosul, College of Education for Pure Science

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Comprehensive analysis of RNA sequencing reveals DNA damage response and immune-associated alternative splicing and RBP regulators contributing to preeclampsia
Artículo
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Comprehensive analysis of RNA sequencing reveals DNA damage response and immune-associated alternative splicing and RBP regulators contributing to preeclampsia
YanHua Wang et al · BMC · 2026 · ISSN 1471-2164
Abstract Background Preeclampsia (PE), a life-threatening hypertensive disorder of pregnancy, remains poorly characterized at the post-transcriptional regulation level. While alternative splicing (AS) perturbations drive...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:GeneticsIdioma eng
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Comprehensive safety analysis of the clinical spectrum of adverse events associated with immune checkpoint inhibitors based on FAERS
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Comprehensive safety analysis of the clinical spectrum of adverse events associated with immune checkpoint inhibitors based on FAERS
Caihong Qu et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
BackgroundThe toxicities associated with immune checkpoint inhibitors (ICIs) can affect nearly all organ systems. Although previous studies have examined specific types of immune-related adverse events (irAEs) associated...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Computational multi-omics integration suggests an association between LAMA3 expression, immune suppression, and metabolic programs in pancreatic ductal adenocarcinoma
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Computational multi-omics integration suggests an association between LAMA3 expression, immune suppression, and metabolic programs in pancreatic ductal adenocarcinoma
Ruixiang Li et al · Springer · 2026 · ISSN 2730-6011
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy in which immune dysregulation and metabolic remodeling are common features. Laminin subunit alpha 3 (LAMA3), a component of lamini...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Controlled Activation of NLR-Mediated Immunity in Roots Using a Copper-Inducible Expression System
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Controlled Activation of NLR-Mediated Immunity in Roots Using a Copper-Inducible Expression System
Hiroshi Yoshida et al · The American Phytopathological Society · 2026 · ISSN 0894-0282
Plant nucleotide-binding leucine-rich repeat receptors (NLRs) function in both shoots and roots as key components of plant immunity, yet their biological roles in roots remain poorly understood. Here, we established a co...
LCC TENDOk1pY3JvYmlvbG9neQ~~; TENDOkJvdGFueQ~~Idioma eng
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Dysregulated m6A RNA methylation in tuberculosis: association with altered methyltransferase expression and immune responses
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Dysregulated m6A RNA methylation in tuberculosis: association with altered methyltransferase expression and immune responses
Yunyi Xu et al · BMC · 2026 · ISSN 1471-2334
Abstract Objective Tuberculosis (TB) remains a global health threat with an incompletely understood pathogenesis. The RNA epigenetic modification N6-methyladenosine (m6A) is a key regulator of immune responses in various...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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EXT2 promotes sarcoma progression and immune evasion via the AKT/c-Myc/PD-L1 axis: a multi-omics and validation study
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EXT2 promotes sarcoma progression and immune evasion via the AKT/c-Myc/PD-L1 axis: a multi-omics and validation study
Haotian Qin et al · BMC · 2026 · ISSN 1479-5876
Abstract Background Sarcomas are a heterogeneous group of mesenchymal malignancies with diverse histological subtypes, limited treatment options, and generally poor outcomes in advanced disease. EXT2, a glycosyltransfera...
LCC LCC:MedicineIdioma eng
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From empirical vaccinology to predictive systems-based vaccine design: multi-omics integration, artificial intelligence, and global equity challenges
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From empirical vaccinology to predictive systems-based vaccine design: multi-omics integration, artificial intelligence, and global equity challenges
Nicole Simone De Lima Coelho et al · Frontiers Media S.A · 2026 · ISSN 2674-0702
Although vaccination remains one of the most impactful interventions in contemporary public health, with consistent and widely documented reductions in morbidity and mortality, the traditional empirical development of va...
LCC TENDOlBoeXNpb2xvZ3k~Idioma eng
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Integrated characterization of distinct immune subtypes linked to drug responsiveness in breast cancer
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Integrated characterization of distinct immune subtypes linked to drug responsiveness in breast cancer
Min Liu et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
IntroductionPrecision medicine emphasizes accurate patient stratification. However, existing molecular frameworks often fail to fully capture the intrinsic heterogeneity of breast cancer (BRCA). This study aims to establ...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Multi-omics analysis identifies NFIL3 as a hypoxia-associated immune regulator in septic cardiomyopathy
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Multi-omics analysis identifies NFIL3 as a hypoxia-associated immune regulator in septic cardiomyopathy
Haibei Sun et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
BackgroundSepsis is a life-threatening syndrome caused by a dysregulated host response to infection and is associated with high mortality in intensive care units. Septic cardiomyopathy (SCM) is a frequent and severe comp...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Orchestrating the pre-metastatic niche: roles of stromal mediators and immune cells in metastatic progression and therapeutic targeting
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Orchestrating the pre-metastatic niche: roles of stromal mediators and immune cells in metastatic progression and therapeutic targeting
Yihao Zhai et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Tumor metastasis is the leading cause of mortality in patients with malignant cancers, and the establishment of the pre-metastatic niche (PMN) is recognized as a pivotal step in this process. With growing insight into th...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Sensitization to amphetamine occurs simultaneously at immune level and in met-enkephalin of the nucleus accumbens and spleen: An involved NMDA glutamatergic mechanism
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Sensitization to amphetamine occurs simultaneously at immune level and in met-enkephalin of the nucleus accumbens and spleen: An involved NMDA glutamatergic mechanism
Assis, Maria Amparo et al · Elsevier · 2009 · ISSN 0889-1591
Administration of psychostimulants can elicit a sensitized response to the stimulating and reinforcing properties of the drugs, although there is scarce information regarding their effects at immune level. We previously ...
Idioma eng
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The mediating effect of immune-inflammatory indices in shift work and hypertension: a cohort study in China
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The mediating effect of immune-inflammatory indices in shift work and hypertension: a cohort study in China
Haixia Lu et al · Nordic Association of Occupational Safety and Health (NOROSH) · 2026 · ISSN 0355-3140
OBJECTIVES: Global hypertension prevalence is increasing. Studies of the association of shift work with hypertension have produced inconsistent results, and the role of immune-inflammatory indices in this link remains un...
LCC LCC:Public aspects of medicineIdioma eng
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Effects of parenteral supplementation with minerals and vitamins on oxidative stress and humoral immune response of weaning calves
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Effects of parenteral supplementation with minerals and vitamins on oxidative stress and humoral immune response of weaning calves
Mattioli, Guillermo Alberto et al · Molecular Diversity Preservation International · 2020 · ISSN 2076-2615
We aimed to evaluate the effects of injectable mineral and vitamin supplementation on weaning calves subjected to a low-stress (fence-line) weaning system. Seven-month-old Aberdeen Angus female calves (n = 40, 152 ± 11 ...
Idioma eng
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Ketamine decreases inflammatory and immune pathways after transient hypoxia in late gestation fetal cerebral cortex
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Ketamine decreases inflammatory and immune pathways after transient hypoxia in late gestation fetal cerebral cortex
Chang, Eileen I. et al · Wiley Blackwell Publishing, Inc · 2016 · ISSN 2051-817X
Transient hypoxia in pregnancy stimulates a physiological reflex response that redistributes blood flow and defends oxygen delivery to the fetal brain. We designed the present experiment to test the hypotheses that trans...
Idioma eng
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Cardiac Complexity Predicts Increased Immune Diagnostic Burden in 22q11.2 Deletion Syndrome
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Cardiac Complexity Predicts Increased Immune Diagnostic Burden in 22q11.2 Deletion Syndrome
Jasmyn Atalla et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Background22q11.2 deletion syndrome (DS) is the second most common cause of congenital heart disease (CHD) and a multisystem disorder that contributes to substantial overall disease burden. Additionally, 22q11.2DS is the...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Crosstalk between the microbiome and the mucosal immunoglobulin A system in the lung, in health and disease
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Crosstalk between the microbiome and the mucosal immunoglobulin A system in the lung, in health and disease
Corentin Stavart et al · Frontiers Media S.A · 2026 · ISSN 2235-2988
The lung, and more specifically the airway epithelium, is continuously exposed to a wide range of inhaled environmental agents. Acting as a frontline physical and biochemical barrier, the airway epithelium orchestrates e...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Oleate alters the immune response in non-small cell lung adenocarcinoma through regulation of HMGB1 release
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Oleate alters the immune response in non-small cell lung adenocarcinoma through regulation of HMGB1 release
Breanna Cole-Skinner et al · Frontiers Media S.A · 2024 · ISSN 2296-634X
BackgroundCancer cell evasion of the immune response is critical to cancer development and metastases. Clinicians' ability to kickstart the immune system to target these rogue cells is an ever-growing area of research an...
LCC LCC:Biology (General)Idioma eng
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Revitalizing therapies in autoimmune diseases: nanoparticles as alternative therapeutic tools
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Revitalizing therapies in autoimmune diseases: nanoparticles as alternative therapeutic tools
Karen Álvarez et al · Universidad de Antioquia · 2024 · ISSN 2145-7166
Autoimmune diseases, such as systemic lupus erythematosus (SLE), are complex disorders characterized by an abnormal immune response. In these diseases, the immune system mistakenly identifies different body components as...
LCC LCC:Biology (General)Idioma eng
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Target-modified low-molecular-weight pectin restores intestinal immune homeostasis in cyclophosphamide-induced immunocompromised mice
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Target-modified low-molecular-weight pectin restores intestinal immune homeostasis in cyclophosphamide-induced immunocompromised mice
Dong Li et al · Elsevier · 2026 · ISSN 1756-4646
The targeted-modified low-molecular-weight pectin (LMP), a natural polysaccharide derived from citrus fruits, represents a promising food-derived immunomodulatory agent. This study assessed the efficacy of targeted-modif...
LCC LCC:Nutrition. Foods and food supplyIdioma eng
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Detection and characterization of Fosfolipase A2 (PLA2) in Caiman latirostris and Caiman yacare plasma
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Detection and characterization of Fosfolipase A2 (PLA2) in Caiman latirostris and Caiman yacare plasma
Siroski, Pablo Ariel et al · Zoological Society of Japan · 2013 · ISSN 0289-0003
Reptiles proved to have a versatile and efficient nonspecific immune system adapted to the environment where they commonly live. Phospholipase A2 (PLA2) is important hydrolytic enzyme involved in the regulation of specif...
Idioma eng
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A Novel Immunomodulatory Strategy to Control Multiple Immune Dysregulation Disorders in a Pediatric Patient
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A Novel Immunomodulatory Strategy to Control Multiple Immune Dysregulation Disorders in a Pediatric Patient
Jennifer D. Blackwood et al · Rockefeller University Press · 2026 · ISSN 3065-8993
Immune dysregulation can lead to autoimmunity and autoinflammation. The goal of treatment is to balance targeted therapies while avoiding infections or other side effects, which becomes complicated with multiple diagnose...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Analysis of the tumor reactivity of autologous TILs and allogeneic γδ T cells via tumor organoid–immune cell coculture
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Analysis of the tumor reactivity of autologous TILs and allogeneic γδ T cells via tumor organoid–immune cell coculture
Zijun Su et al · BMC · 2026 · ISSN 1479-5876
Abstract Background The efficacy of conventional αβ T cell-based immunotherapies is often limited by tumor immune evasion. γδ T cells can bypass these limitations through MHC-independent tumor recognition, but their ...
LCC LCC:MedicineIdioma eng
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Blood cell ratio biomarkers of systemic inflammation in chronic obstructive pulmonary disease
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Blood cell ratio biomarkers of systemic inflammation in chronic obstructive pulmonary disease
Kaman So et al · BMC · 2026 · ISSN 1465-993X
Abstract Background Blood eosinophil count is an accepted biomarker for type 2 inflammation in COPD. However, the majority of COPD patients are characterized by non-type 2 inflammation. We aimed to test readily obtainabl...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSByZXNwaXJhdG9yeSBzeXN0ZW0~Idioma eng
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Curcumin nanoparticles attenuate copper nanoparticle-induced systemic toxicity in rats: a proof-of-concept study for a systemic protective strategy
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Curcumin nanoparticles attenuate copper nanoparticle-induced systemic toxicity in rats: a proof-of-concept study for a systemic protective strategy
Asmaa S. Morsi et al · SpringerOpen · 2026 · ISSN 2190-4715
Abstract Copper oxide nanoparticles (CuO-NPs) are known to trigger systemic toxicity through the disruption of copper homeostasis and the generation of profound oxidative stress. Given their widespread industrial applic...
LCC TENDOkVudmlyb25tZW50YWwgc2NpZW5jZXM~; LCC:Environmental lawIdioma eng
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