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IntroductionSkin cancer, including basal cell carcinoma, squamous cell carcinoma, and melanoma, is one of the most common cancers worldwide. Matrix metalloproteinases are zinc-dependent proteolytic enzymes that play a cr...

Abstract Background The overall incidence of pituitary apoplexy among patients with pituitary adenoma ranges from 0.6% to 7.0%, although many cases likely go undiagnosed. Several precipitating factors have been identifie...

Background: Melanoma represents a highly aggressive and metastatic form of malignant skin cancer. that remains challenging to treat clinically. Tumor cells often reprogram nicotinamide adenine dinucleotide (NAD⁺) metab...

ABSTRACT Oral neoplasms are classified as non-odontogenic, predominantly malignant, and odontogenic, typically benign. Melanoma is a malignant tumor arising from melanocytes and nevus cells, found in the skin and mucous ...

Abstract Melanomas of the female genital tract may occur in the vulva, the vagina, the ovary or the cervix.Pregnancy has been considered an aggravating factor in the evolution and prognosis of melanoma. A 35-year-old fem...

Abstract Background Oral melanoma (OM) and oral squamous cell carcinoma (OSCC) are frequently diagnosed in dogs, presenting a challenge in distinguishing them from benign oral tumors (BN). Salivary metabolomic biomarkers...

Abstract Background Uveal melanoma (UM) is a rare disease, but the most common intraocular malignancy in adults, with incidence rates in Europe ranging from 1.3 to 8.6 cases per million annually. Although local tumor con...

Abstract Background Adoptive cell therapy with tumour-infiltrating lymphocytes has been recognised as a safe and effective treatment for patients with advanced melanoma. Whether such a novel intervention is cost-effectiv...

Materias / palabras clave: cutaneous melanoma; vitamin d receptor; polymorphism; meta-analysis

Introduction Mucosal melanoma (MM) carries a high risk of postoperative relapse and poorer survival than cutaneous disease. Prospective data from China support adjuvant temozolomide–cisplatin (TMZ/DDP) in resected MM, ...

Abstract Immunotherapy has transformed melanoma treatment, yet only a subset of patients benefit and clinically effective biomarkers remain limited. Here, we report a comprehensive analysis evaluating CD27 as a predictiv...

B16F10 cells are a murine melanoma cell line characterized by high metastatic potential and resistance to various treatments. Studies indicate that cancer can cause significant alterations in the heart's electrical condu...

Abstract Despite advances in therapy, survival rates for metastatic melanoma remain low. Drug-tolerant persister cells (persisters) can facilitate cancer recurrence, yet their characteristics and vulnerabilities differ a...

Abstract Since the first report in 1972, several studies have documented an association between Parkinson’s disease (PD) and melanoma. Up to 20-fold increased risk of melanoma was reported in PD patients, while a perso...

Con el objetivo de evaluar la viabilidad del trasplante de un melanoma canino en ratones inmunodeficientes, 3 ratones N:NIH (S)-Fox1 nu libres de patógenos específicos de 6 semanas de edad se trasplantaron por vía sub...

BACKGROUND: An improvement in overall survival among patients with metastatic melanoma has been an elusive goal. In this phase 3 study, ipilimumab--which blocks cytotoxic T-lymphocyte-associated antigen 4 to potentiate a...

Materias / palabras clave: Melanoma; Treatment; Vaccines; Cáncer; Vacuna

Trabajo Final Integrador de Ingeniería En este trabajo se desarrolló una herramienta de asistencia diagnóstica, basada en procesamiento de imágenes dermatológicas e inteligencia artificial que asiste al dermatólogo...