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Abstract Objective Myelodysplastic syndromes (MDS) are associated with a high risk of progression to leukemia, highlighting the critical need to explore novel therapeutic agents. Based on network pharmacology predicti...

Abstract Man-made synthetic/manufactured nano-objects (MNOs) are increasingly used in almost every scientific sector, including pharmaceutical, agricultural, food, and drug industries worldwide. Rapid advances in nanotec...

Abstract Hydrogen generation from renewable energy sources allows balancing the intermittent nature of solar and wind power. The chemical energy stored in hydrogen can be efficiently converted back to electricity using f...

The significant rise in implementation and applications of plasmonic nanosystems in biophysics, biochemistry, and medicine has culminated in the emergence of refined plasmonic enabling reagents, or “nanoagents”. Thes...

Background: Preterm birth (PTB) is the leading cause of perinatal morbimortality worldwide. Genetic and environmental factors could raise PTB risk. The aim of this study was to analyze the contribution of the statistical...

Objective: Phosphatase and tensin homolog (PTEN) is a critical regulator of cell proliferation, differentiation, and inflammatory balance. However, its downstream proteomic effects in periodontal ligament stem cells (PDL...

Abstract Selenium (Se) enriched forest-grown ginseng is famous for its high Se content and excellent protein quality, which are necessary for varieties of metabolic processes and play an important role in both ginseng gr...

Exosomes, as key mediators of intercellular communication, play a central regulatory role in cellular physiological and pathological processes through their dynamic interaction with the cytoskeleton. The cytoskeleton is ...

ABSTRACT Cells rely on surface receptors to sense and initiate signalling cascades essential for numerous cellular processes, but engineering of synthetic genetic circuits to sense and rewire receptor activities for user...

We performed a systematic approach using statistical tools to understand the effect of the water chemistry on removal of microorganisms using ultrafiltration. We applied a four-factor at two-level factorial design with c...

Tetrahymena es el eucariota unicelular ciliado no patógeno más estudiado y empleado a nivel biotecnológico, pues combina la complejidad de procesos celulares típicos presentes en eucariotas con una gran facilidad de ...

ABSTRACT Background Intervertebral disc degeneration (IVDD), a prevalent spinal disorder, is closely associated with abnormal mechanical stress. The nucleus pulposus (NP), annulus fibrosus (AF), and cartilaginous endplat...

Heme (iron protoporphyrin IX) is an important molecule involved in many biological reactions, including oxygen transport, respiration, photosynthesis and drug detoxification. Trypanosoma cruzi parasites, the etiological ...

Arterial Tortuosity Syndrome (ATS) is a rare autosomal recessive connective tissue disorder caused by mutations in the SLC2A10 gene encoding the glucose transporter GLUT10. GLUT10 deficiency leads to the accumulation of ...

In this work we carried out an ultrastructural analysis of the cell interface between oocyte and follicle cells during the oogenesis of the amphibian Ceratophrys cranwelli, which revealed a complex cell-cell interaction....

The interactions of proteins with membrane surfaces are important to many biological processes, including signaling, recognition, and membrane trafficking, cell division and cell structure. When the Fluid Mosaic Model (F...

A fluid mosaic model is presented for the gross organization and structure of the proteins and lipids of biological membranes. The model is consistent with the restrictions imposed by thermodynamics. In this model, the p...

Tesis de licenciatura El gen Gpm6a fue identificado como un gen de respuesta al estrés en animales sometidos a diferentes modelos de estrés crónico. En humanos, diferentes patologías neuropsiquiátricas se han asocia...

Los procesos biogeoquímicos relacionados con la dinámica de nutrientes, isótopos estables, ácidos grasos marcadores y el plancton fueron estudiados en un lago salino de la Pampa Argentina. El amonio fue el compuest...

"El objetivo general de la tesis fue profundizar el conocimiento de las interacciones presentes en las interfases entre superficies, microorganismos y nanomateriales en medios acuosos. En particular se estudiaron las int...

Mechanotransduction is a process where cells sense their surroundings and convert the physical forces in their environment into an appropriate response. Calcium plays a crucial role in the translation of such forces to b...

At high concentrations, free radicals and radical-derived, nonradical reactive species are hazardous for living organisms and damage all major cellular constituents. At moderate concentrations, however, nitric oxide (NO)...