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Abstract Background Tauopathies are a group of neurodegenerative diseases, including Alzheimer’s disease (AD), characterized by progressive accumulation of pathological Tau proteins. Among the diverse Tau species, trun...

Neurotransmitter receptors of the Cys-loop superfamily mediate rapid synaptic transmission throughout the nervous system, and include receptors activated by ACh, GABA, glycine and serotonin. They are involved in physiolo...

Key Points. Regulatory T cells (Tregs) from people (control, type 1 diabetes with and without albuminuria) were profiled for phenotypic and transcriptomic changes. Central memory Tregs were reduced, while Treg EMRA+ cell...

BackgroundTelomere biology disorders (TBD) are rare multisystem disorders characterized by a wide array of clinical presentations, including bone marrow failure, pulmonary fibrosis, and malignancy predisposition due to p...

The pandemic of COVID-19 left profound global impacts on public health, economics, and social dynamics. Since its emergence, the virus has spread across 229 countries, infecting over 590 million individuals and causing 7...

O Transtorno do Déficit de Atenção/Hiperatividade (TDAH) é o diagnóstico psiquiátrico mais frequente entre crianças com problemas de aprendizagem. Os sujeitos com TDAH apresentam problemas de memória operacional,...

BackgroundRecurrent bacterial pneumonia accompanied by atypical systemic findings may indicate an uncharacterized inborn error of immunity (IEI). We report a 10-year-old male with recurrent pneumonias, mildly low but fun...

IntroductionToll-like receptor 8 gain-of-function (TLR8 GOF) is a recently described inborn error of immunity caused by activating mutations in Tlr8. Pathogenic variants lead to constitutive signaling in myeloid cells an...

Introduction: According to statistics, the number of students with disability at Lviv Polytechnic National University is 374 people; the number of veteran-students is 6; the number of students-children of veterans is 811...

Trauma is an encounter of the violent event, with its unexpectedness and horror. Traumatic disorders transpire when there is an interplay between the experience and memory along with their gender violence. The most destr...

The serotonergic system and more precisely the serotonin type 2Areceptor (5-HT2AR) is involved in a wide variety of cognitive and emotionalfunctions. In recent studies, it has been found that 5-HT2AR participates inthe p...

Thirty years of brain imaging research has converged to define the brain's default network-a novel and only recently appreciated brain system that participates in internal modes of cognition. Here we synthesize past obse...

BACKGROUND: Subjects with a mild cognitive impairment (MCI) have a memory impairment beyond that expected for age and education yet are not demented. These subjects are becoming the focus of many prediction studies and e...

Materias / palabras clave: geriatrics, dementia risk factors, dementia detection, biomarkers, memory disorders; Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system; Medicine...

Materias / palabras clave: alzheimer's disease, dementia, memory disorders, dementia risk factors, neurodegenerative diseases; Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous s...