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Galactose alters early-life development and exerts sex-specific nutritional programming effects on lifespan in Drosophila melanogaster
Artículo
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Galactose alters early-life development and exerts sex-specific nutritional programming effects on lifespan in Drosophila melanogaster
Peixin Sun et al · Frontiers Media S.A · 2026 · ISSN 2296-861X
BackgroundNutritional programming by early-life nutrition exerts long-lasting effects on later-life health. In mammals, galactose, as a component of the milk sugar lactose, is consumed during lactation. Mouse studies sug...
LCC LCC:Nutrition. Foods and food supplyIdioma eng
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Global and regional prevalence, burden, and risk factors for MASLD in children and adolescents aged 5 to 24 years: a systematic review, meta-analysis, and modeling study
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Global and regional prevalence, burden, and risk factors for MASLD in children and adolescents aged 5 to 24 years: a systematic review, meta-analysis, and modeling study
Yunfei Liu et al · BMC · 2026 · ISSN 1741-7015
Abstract Background Obesity is associated with metabolic dysfunction-associated steatotic liver disease (MASLD). Despite the rising prevalence of obesity among children and adolescents, no studies have examined risk fact...
LCC LCC:MedicineIdioma eng
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Kynurenine promotes angiogenesis through mTOR signaling in head and neck squamous cell carcinoma
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Kynurenine promotes angiogenesis through mTOR signaling in head and neck squamous cell carcinoma
Shuoqi Lin et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Angiogenesis and its maturation play a crucial role in the progression and prognosis of head and neck squamous cell carcinoma (HNSCC). Tumor growth relies on an adequate blood supply to meet metabolic demands, w...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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OneSTOP (One-Stop Telehealth Obesity Program): study protocol for an open-label randomized controlled trial on the use of telecare and digital platforms for multidisciplinary management of weight management and related comorbidities
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OneSTOP (One-Stop Telehealth Obesity Program): study protocol for an open-label randomized controlled trial on the use of telecare and digital platforms for multidisciplinary management of weight management and related comorbidities
Joan Khoo et al · BMC · 2026 · ISSN 1745-6215
Abstract Background Obesity is prevalent in Singapore and is a driver of multiple co-morbidities including type 2 diabetes, metabolic dysfunction associated steatotic liver disease (MASLD), and cardiovascular disease. Tr...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Research Progress on Nanoformulations Based on Active Components from Traditional Chinese Medicine for MASLD
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Research Progress on Nanoformulations Based on Active Components from Traditional Chinese Medicine for MASLD
Gou ZX et al · Dove Medical Press · 2026 · ISSN 1178-2013
Zi-Xiu Gou, Ning-Wei Li, Jun-Yi Yao, Yun-Liang Wang Department of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of ChinaCorrespondence: Yun-Liang Wang, Departme...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Stimulated Raman scattering microscopy: fundamentals, instrumentation, and chemical imaging applications
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Stimulated Raman scattering microscopy: fundamentals, instrumentation, and chemical imaging applications
Fake Lu · Frontiers Media S.A · 2026 · ISSN 2813-530X
Stimulated Raman scattering (SRS) microscopy is a fast Raman imaging technique that combines the molecular specificity of vibrational spectroscopy with the high spatial resolution and speed of laser-scanning microscopy. ...
LCC LCC:Biology (General); TENDOkNoZW1pc3RyeQ~~Idioma eng
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The Importance of Resistance Training in Addressing Insulin Resistance and Type 2 Diabetes: A Narrative Review
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The Importance of Resistance Training in Addressing Insulin Resistance and Type 2 Diabetes: A Narrative Review
Katarzyna et al · Nicolaus Copernicus University in Toruń · 2026 · ISSN 2450-3118
Introduction: Insulin resistance and type 2 diabetes mellitus are serious global health challenges, which are caused by aging population, increasing levels of obesity and insufficient amount of physical activity. Althoug...
LCC TENDOlNwb3J0cw~~; TENDOlNwb3J0cyBtZWRpY2luZQ~~Idioma eng
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The Association Between Sugar-Sweetened Beverage (SSB) Consumption and Gut Microbiota Composition and Related Metabolites in Adults: A Systematic Review
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The Association Between Sugar-Sweetened Beverage (SSB) Consumption and Gut Microbiota Composition and Related Metabolites in Adults: A Systematic Review
Kamila Kamińska et al · Kazimierz Wielki University · 2026 · ISSN 2391-8306
Background. Sugar-Sweetened Beverages (SSB) are a major source of dietary sugars worldwide. Emerging evidence suggests that dietary factors, including sugar intake, may influence the composition of the gut microbiota, wh...
LCC TENDOkVkdWNhdGlvbg~~; TENDOlNwb3J0cw~~; LCC:MedicineIdioma eng
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The Effect of Two Different Bicarbonate-Containing Dialysis Solutions on Acidosis Control in Hemodialysis Patients
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The Effect of Two Different Bicarbonate-Containing Dialysis Solutions on Acidosis Control in Hemodialysis Patients
İsmail BALOĞLU et al · Turkish Society of Nephrology · 2019 · ISSN 2667-4440
OBJECTIVE: In hemodialysis patients; there is a continuing tendency to metabolic acidosis. In studies, the relationship between serum bicarbonate concentration and dialysis mortality has been determined. In our study, th...
LCC LCC:Internal medicine; TENDOlBlZGlhdHJpY3M~Idioma eng
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The enzymatic mechanisms of lactylation and its role in gynecological diseases: a comprehensive review
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The enzymatic mechanisms of lactylation and its role in gynecological diseases: a comprehensive review
Min Zhang et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Lysine lactylation (Kla) is a novel form of post-translational modification. It utilizes lactate as its core substrate. Through an enzymatic regulatory network, it mediates modifications of both histones and non-histone ...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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The interplay between gut microbiota metabolites and host body: Implications in health and disease
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The interplay between gut microbiota metabolites and host body: Implications in health and disease
Md. Monirul Islam et al · Elsevier · 2026 · ISSN 2666-1497
The gut microbiota has co-evolved with its host and forms an essential component of the human body. It is acquired at birth and continues to develop alongside the host, preserving its diversity and stability throughout l...
LCC LCC:Nutrition. Foods and food supply; LCC:Nutritional diseases. Deficiency diseasesIdioma eng
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Thermogenic capacity in subterranean Ctenomys: Species-specific role of thermogenic mechanisms
Artículo
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Thermogenic capacity in subterranean Ctenomys: Species-specific role of thermogenic mechanisms
Luna, Facundo et al · Pergamon-Elsevier Science Ltd · 2019 · ISSN 0306-4565
One way to understand ecological patterns of species is to determine their physiological diversity on a large geographic and/or temporal scales, in a context of hierarchical biodiversity framework. In particular, macroph...
Idioma eng
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Comparison of the effects of 7.2% hypertonic saline and 20% mannitol on electrolyte and acid‐base variables in dogs with suspected intracranial hypertension
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Comparison of the effects of 7.2% hypertonic saline and 20% mannitol on electrolyte and acid‐base variables in dogs with suspected intracranial hypertension
Sabrina N. Hoehne et al · Oxford University Press · 2021 · ISSN 0891-6640
Abstract Background Hyperosmolar agents frequently are used to decrease intracranial pressure but their effects on electrolyte and acid‐base variables have not been prospectively investigated. Objectives Compare durati...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Short‐term effects of canagliflozin on glucose and insulin responses in insulin dysregulated horses: A randomized, placebo‐controlled, double‐blind, study
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Short‐term effects of canagliflozin on glucose and insulin responses in insulin dysregulated horses: A randomized, placebo‐controlled, double‐blind, study
Sanna Lindåse et al · Oxford University Press · 2023 · ISSN 0891-6640
Abstract Background Decreasing hyperinsulinemia is crucial in preventing laminitis in insulin dysregulated (ID) horses. Complementary pharmacological treatments that efficiently decrease postprandial hyperinsulinemia in ...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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The association between the triglyceride-glucose index and serum uric acid: a systematic review and meta-analysis
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The association between the triglyceride-glucose index and serum uric acid: a systematic review and meta-analysis
Lanlan Feng et al · BMC · 2026 · ISSN 1472-6823
Abstract Background The triglyceride-glucose (TyG) index has emerged as a surrogate marker for insulin resistance. This systematic review and meta-analysis of observational studies aimed to investigate the association be...
LCC LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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Grapevine tissues and phenology differentially affect soluble carbohydrates determination by capillary electrophoresis
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Grapevine tissues and phenology differentially affect soluble carbohydrates determination by capillary electrophoresis
Moreno, Daniela Maria del Valle et al · Elsevier France-editions Scientifiques Medicales Elsevier · 2017 · ISSN 0981-9428
Soluble carbohydrates distribution depends on plant physiology and, among other important factors, determines fruit yield and quality. In plant biology, the analysis of sugars is useful for many purposes, including metab...
Idioma eng
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Pharmacokinetics, distribution, metabolism, excretion and safety characterization of ZJCK-6-72: novel DYRK1A inhibitor with optimized brain exposure for Alzheimer’s disease therapy
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Pharmacokinetics, distribution, metabolism, excretion and safety characterization of ZJCK-6-72: novel DYRK1A inhibitor with optimized brain exposure for Alzheimer’s disease therapy
Zhenshu Li et al · Frontiers Media S.A · 2026 · ISSN 1663-9812
Developing effective drugs for Alzheimer’s Disease (AD) is critically limited by insufficient brain exposure. To address this, structural optimization was employed to balance physicochemical properties and enhance bloo...
LCC LCC:Therapeutics. PharmacologyIdioma eng
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A Multidisciplinary Intragastric Balloon Care Pathway for Weight Management in a Tertiary Malaysian Centre: Clinical Practice Framework
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A Multidisciplinary Intragastric Balloon Care Pathway for Weight Management in a Tertiary Malaysian Centre: Clinical Practice Framework
Gill T et al · Dove Medical Press · 2026 · ISSN 1178-2390
Theeran Gill, Guo Hou Loo, Guhan Muthkumaran, Nik Ritza Kosai Upper GI & Metabolic Surgery Unit, Department of Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, MalaysiaCorrespondence: Guo H...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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A ptsH mutation suppresses growth defects and antibiotic sensitivity in a cpgA mutant defective in metabolite proofreading
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A ptsH mutation suppresses growth defects and antibiotic sensitivity in a cpgA mutant defective in metabolite proofreading
Ankita J. Sachla et al · American Society for Microbiology · 2025 · ISSN 0021-9193
ABSTRACT Bacillus subtilis CpgA (circularly permuted GTPase) is a ribosome assembly GTPase that has a secondary function as a metabolite proofreading enzyme. CpgA hydrolyzes 4-phosphoerythronate, a toxic metabolite produ...
LCC LCC:MedicineIdioma eng
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Advanced single-cell transcriptomics deciphers cellular complexity and MIF-orchestrated signaling networks in diabetes-induced myocardial disease
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Advanced single-cell transcriptomics deciphers cellular complexity and MIF-orchestrated signaling networks in diabetes-induced myocardial disease
Zhenyu Lin et al · Elsevier · 2026 · ISSN 2472-6303
Background: Cardiac complications arising from diabetes mellitus manifest as structural and functional myocardial alterations independent of traditional cardiovascular risk factors. The intricate molecular underpinnings ...
LCC TENDOkJpb3RlY2hub2xvZ3k~; TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma eng
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Advances on the edible safety and biological activities of L-Ergothioneine
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Advances on the edible safety and biological activities of L-Ergothioneine
MA Sheng et al · The Editorial Office of Chinese Journal of Food Hygiene · 2025 · ISSN 1004-8456
L-Ergothioneine （L-EGT） is a histidine-derived compound widely present in edible mushrooms， certain legumes， animal organ meats， which must be obtained through dietary intake as it can’t be synthesized by hum...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Nutrition. Foods and food supplyIdioma zho
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Are serum MOTS-c levels and MOTS-c m.1382A>C polymorphism related to polycystic ovary syndrome?
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Are serum MOTS-c levels and MOTS-c m.1382A>C polymorphism related to polycystic ovary syndrome?
Berna Eroğlu Filibeli et al · Sociedade Brasileira de Endocrinologia e Metabologia · 2026 · ISSN 2359-4292
Abstract Objective: MOTS-c is a mitochondria-derived peptide associated with reduced insulin resistance and obesity. The m.1382A>C polymorphism of the MOTS-c gene is linked to an increased risk of type 2 diabetes in men...
LCC LCC:Medicine; LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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Arsenic bioaccumulation and biotransformation in macroalgae: Arsenosugar complexity and multifactor variability
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Arsenic bioaccumulation and biotransformation in macroalgae: Arsenosugar complexity and multifactor variability
Lizhao Chen et al · Elsevier · 2026 · ISSN 0147-6513
Arsenic (As) is a toxic metalloid, and its accumulation in macroalgae has raised concerns for aquatic ecosystem health and human food safety given the increasing consumption of macroalgae. While previous studies have pre...
LCC LCC:Environmental pollution; TENDOkVudmlyb25tZW50YWwgc2NpZW5jZXM~Idioma eng
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Association Between Dietary Tea Consumption and Non‐Alcoholic Fatty Liver Disease: A Systematic Review and Meta‐Analysis
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Association Between Dietary Tea Consumption and Non‐Alcoholic Fatty Liver Disease: A Systematic Review and Meta‐Analysis
Amogh Verma et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background Non‐Alcoholic Fatty Liver Disease (NAFLD) is a significant global health concern linked with metabolic syndrome, affecting approximately 25% of the global population. It leads to severe liver compli...
LCC LCC:MedicineIdioma eng
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