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Introduction . It is estimated that erythroderma affects about 1–2% of patients with psoriasis. Objective . To present a case of psoriatic erythroderma, which was effectively treated with cyclosporin A. Case repor...

Psoriasis is a chronic, immune-mediated inflammatory disorder that has a significant negative impact on patients’ quality of life. In addition to the physical manifestations of cutaneous lesions and potential joint i...

Materias / palabras clave: psoriasis; connective tissue; cutaneous lupus erythematosus

Materias / palabras clave: psoriasis; fetuin-a; endothelin-1; endocan

Materias / palabras clave: adipokines; cardiometabolic risk; obesity; psoriasis severity

Materias / palabras clave: psoriasis; nitric oxide; resistin; blood; gene expression

Objective: The purpose of this paper is to expound the effect of asiatic acid (AA) on psoriasis via modulating the PI3K/Akt/NF-κB pathway and NLRP3 inflammasome. Methods: An imiquimod (IMQ)-induced psoriasis model in BA...

Psychological factors play an important role in aggravating skin diseases, which could lead to increasing the severity of skin diseases, such as psoriasis, atopic dermatitis, acne vulgaris, seborrheic dermatitis, and lic...

The association between cheese consumption and chronic inflammatory skin conditions remains unclear. We used a two-sample bidirectional Mendelian randomization (MR) framework to investigate the genetic causality between ...

Psoriasis is a chronic and recurrent skin disease, affecting 1.5-3% of thepopulation. It is characterized by abnormal epidermal proliferation,immunological disturbances with predominance of Th1 response andcomplex pathog...

Materias / palabras clave: anti-TNF therapy; psoriasis; resistance in therapy; molecular marker

Materias / palabras clave: subcorneal pustular dermatosis; sneddon-wilkinson syndrome; iga pemphigus; pustular psoriasis

ABSTRACT Background and Aims Familial Mediterranean Fever (FMF) is a monogenic autoinflammatory disease caused by mutations in the MEFV gene, resulting in recurrent inflammatory episodes and a risk of developing amyloido...

Immune dysregulation can lead to autoimmunity and autoinflammation. The goal of treatment is to balance targeted therapies while avoiding infections or other side effects, which becomes complicated with multiple diagnose...

BackgroundItchy E3 ubiquitin ligase deficiency (ITCH deficiency) is a rare monogenic immune dysregulation syndrome characterized by early-onset multisystem autoimmunity and significant morbidity and mortality. Only one p...

Abstract IL-22, a signature cytokine for type 3 lymphoid cells, including T helper 17/22 (Th17/22) and type 3 innate lymphoid cells (ILC3), mediates epithelial homeostasis and protective pathogen responses in barrier tis...

Abstract Background Autoimmune conditions are common in women of reproductive age. They are associated with an increased risk of adverse pregnancy outcomes; whether this is causal is unclear. Our aim was to explore the c...

Cutaneous lymphatic vessels are essential for maintaining tissue homeostasis and coordinating immune defence, making them vital to skin health. Recent advances in molecular biology and immunology have revealed the associ...

IntroductionSchnitzler syndrome (SchS) is a rare, late-onset, acquired autoinflammatory disorder characterized by recurrent urticarial lesions, monoclonal gammopathy and systemic inflammation. Although interleukin-1 (IL-...