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Foreign bodies in the external auditory canal (EAC) are a common pediatric emergency, especially in children aged 1–4 years due to exploratory behavior and limited risk awareness. Common objects include beads, toy part...

Abstract Background Prehospital manipulation and reduction (M&R) of traumatic limb injuries may be required before transfer to restore alignment, reduce pain and bleeding, and limit secondary neurovascular compromise. In...

Latar belakang: kandidiasis (kandidosis) adalah infeksi jamur yang disebabkan oleh spesies Candida biasanya Candida albicans. Faktor predisposisi yang memicu kandidiasis adalah terganggunya ekologi mulut karena antara la...

ABSTRACT This study aimed to measure hip laxity using distraction-stress radiography in young crab-eating foxes. Eight free-ranging crab-eating foxes (Cerdocyon thous), six males and two females, with a mean age of 4 mon...

Opioid-free Anaesthesia (OFA) for craniotomy is a method employed increasingly for intraoperative and postoperative pain management with reduced opioid side-effects. Standard opioid regimens, although best for analgesia,...

Abstract Background The repeated administration of high doses of gabapentin may provide better analgesia in horses than current clinical protocols. Hypothesis and Objectives Administration of gabapentin at 40 and 120 m...

Abstract Background This study aimed to develop and validate a nomogram for predicting the risk of prolonged somnolence in hospitalized patients receiving intravenous midazolam. Methods We retrospectively collected clini...

To test clinically whether a small dose of ifenprodil can enhance the anti-hyperalgesic effect of ketamine in dogs, a prospective randomized cross-over study was done with eight mongrel dogs (weighing 16.9 ± 3.7kg). Ani...

Introduction. The 2025 FDA approval of suzetrigine (Journavx) ended a 25-year stagnation in analgesic development. This introduced a paradigm shift in pain management. As a first-in-class, highly selective NaV1.8 sodium...

In the central nervous system (CNS), programmed cell death (PCD) of neurons, is precisely regulated by various biomolecules to maintain neuronal development, establish neural structures, and maintain CNS homeostasis. Und...

Abstract Background Volatile anesthetics are widely used for sedation in intensive care. Being potent greenhouse gases, their efficient utilization is imperative. We investigated whether the efficiency of anesthetic refl...

Background: While the S-enantiomer of Ketamine (S-Ketamine) is described to be more potent than the racemic form (Ra-Ketamine), with a shorter half-life and almost no side effects, both forms have never been compared in ...

Abstract Background Antiseizure medications (ASMs) are essential for seizure control, but they are also associated with a range of adverse events that may affect treatment outcomes. Objective This study aimed to evaluate...

Aloysia citriodora Palau, Verbenaceae ("cedrón") is widely used as infusion or decoction in South America to treat indigestion, tachycardia and anxiety. We previously demonstrated its antispasmodic effect on rat duodenu...

To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008. A consensus committee of 68 international experts representing 30 international...

Materias / palabras clave: anesthesia, pain, critical care, perioperative care, sedation, monitoring; Medicine: Surgery: Anesthesiology