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BackgroundFrontotemporal dementia is an umbrella term that encompasses several clinical syndromes with impaired behavioral, language, and motor functions. These syndromes show considerable overlap in clinical features an...

Abstract Background HC-HA/PTX3 (a complex formed by high molecular weight hyaluronan covalently linked to heavy chain 1 of inter-α-trypsin inhibitor and tightly bound to pentraxin 3) is a unique extracellular matrix fro...

Abstract In many real-world applications, binary and multi-class classification problems involving imbalanced data and overlapping boundaries present a significant challenge for traditional machine learning algorithms. I...

IntroductionLate-life difficult-to-treat depression (LL-DTD) and dementia frequently coexist in later life, but it remains unclear whether clinical and sociodemographic characteristics, as well as medication exposure pat...

Abstract Lithium (Li) recovery from secondary resources, such as mine waters, is essential to meet the increasing global demand. However, lithium in mine waters typically occurs at low concentrations, necessitating effic...

Abstract Background Radiomics analysis of 18F-FDG PET/CT enables extraction of high-dimensional quantitative features that may serve as imaging biomarkers for tumor biology. In particular, in non-small cell lung cancer (...

Abstract Background Hypertension is increasingly recognised among younger adults and contributes to early cardiovascular risk, yet population-level data in this age group remain limited in many low- and middle-income cou...

Forest ecosystems play a fundamental role in sustaining global water cycles and ecological security, and accurate modeling of their eco-hydrological processes is essential for forest management, watershed regulation, and...

Complex interactions between seawater and freshwater govern intrusion and stabilization in coastal aquifers. Previous studies have primarily relied on interface-based analyses, limiting full-field spatial quantification ...

Objective: To explore the imaging biomarkers obtained from baseline multi-modality imaging PET/CT before metastasis-directed therapy (MDT), which could offer early response prediction before MDT treatment, optimizing pat...

The acidic cleaning wastewater generated during printed circuit board(PCB) manufacturing contains copper ions(Cu2+) at concentrations of 2-6 g/L. The recovery of these copper ions holds significant importance for promoti...

Abstract A selective and eco-friendly spectrophotometric approach was developed for the quantitative determination of entacapone (ENT) in the presence of its co-formulated drugs carbidopa (CAR) and levodopa (LEV) which e...

IntroductionThIntrusion Detection Systems (IDS) for Internet of Things (IoT) and edge environments require datasets with unambiguous labels, yet existing datasets often mix benign and malicious traffic within the same ca...

Introduction and aims: Oral microbial biomarkers for metabolic syndrome (MetS), in contrast to its well-characterized relationship with the gut microbiome, have not been well defined. This study aims to systematically id...

Abstract Background Occupational therapy practices are expanding in Turkey; however, pediatric professionals lack validated, client-centered assessment instruments for children with attention-deficit/hyperactivity disord...

Abstract Background Skin disorders are widespread, and there is increasing demand for reliable, standardized herbal therapeutics. Kumkumadi Tailam, a classical Ayurvedic polyherbal oil formulation, incorporates several b...

Background and aimsTongxie Yaofang (TXYF) is a classic prescription for IBS-D with liver depression and spleen deficiency, with its therapeutic mechanisms requiring further elucidation. This study investigated the modula...