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Pediatric cancer poses a major health challenge globally, especially in low-middle-income countries like Indonesia. The survival rate of pediatric cancer in many high-income countries (HICs) reaches 90%, while it only ra...

Abstract Background Modern medical education is transforming from a biomedical focus toward a holistic, patient-centered paradigm that values medical humanistic qualities, such as empathy, communication skills and reflec...

Introduction. The most commonly diagnosed cancer group in humans is cancers of the skin. One pre‑invasive form of squamous cell carcinoma is Bowen's disease. It manifests in the form of single or multiple lesions, whi...

Abstract Tuberculosis (TB) remains a major global public health challenge, with drug-resistant tuberculosis (DR-TB) presenting a serious threat to TB management. Conventional treatment faces challenges such as significan...

Iman Owliaee,1 Ali Teimoori,1 Mohammad Shoushtari,2 Ali Shojaeian3 1Department of Medical Virology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran; 2Department of Virology, Pasteur Institute o...

Background: Marital infidelity is one of the most challenging issues in married life, often leading to adverse psychological outcomes such as depression and diminished self-esteem. This study aimed to examine the impact ...

Purpose: To evaluate the association of lipid profile and statin therapy with stroke severity and early functional outcome in anticoagulated patients with atrial fibrillation (AF) hospitalized with acute ischemic stroke ...

BackgroundClinically, cardiotoxicity defined by reduced left ventricle ejection fraction (LVEF) in cancer therapy could miss the onset of tissue-level myocardial changes. In this study, we aimed to use late gadolinium en...

Background: Adults aged 75 years and older carry the highest absolute risk of cardiovascular disease (CVD) yet remain substantially underrepresented in randomized trials evaluating statin therapy for primary prevention. ...

BackgroundTo compare the prognostic effects of different single antiplatelet therapy (SAPT) regimens (aspirin vs. clopidogrel) in patients with acute coronary syndrome (ACS) at high-risk for ischemia and bleeding followi...

BackgroundPatients with differentiated thyroid cancer (DTC) undergoing radioactive iodine (RAI) therapy experience concurrent physical and psychological symptoms, yet the dynamic interplay among these symptoms remains in...

BackgroundThis study investigated whether manual therapy applied to tendon organs ameliorated neuromuscular dysfunction in rats with spasticity induced by upper motor neuron injury associated with spastic cerebral palsy,...

Abstract Background Chronic Insomnia Disorder (CID) is a prevalent condition. This study examines microbaric oxygen therapy (MOT) as a non-pharmacological intervention for CID patients, utilizing EEG to investigate its e...

ABSTRACT Breast cancer is the most common type of cancer and the leading cause of cancer-related death among women worldwide. Hormone receptor-positive (HRþ) tumors represent the most common form of this disease, with m...

Bladder cancer is a highly malignant tumor with limited treatment options. Although adoptive cell therapy has shown promise in oncology, its efficacy is often constrained by poor intrinsic antitumor activity and a highly...

Abstract Background Radiation therapy is commonly used as an adjunct to incomplete surgical excision in dogs with mast cell tumors (MCT), but the optimal dose and fractionation regimen have yet to be determined. Hypothes...

Abstract Objective: Attention-deficit/hyperactivity disorder (ADHD) affects approximately 7% of children and 5% of adolescents worldwide. ADHD is characterized by inattention, hyperactivity and impulsivity as symptoms. ...

Photodynamic therapy (PDT) has lately been identified as a promising anticancer method and gained tremendous interest due to its controllability, non-invasive nature, and negligible side effects. Nevertheless, the develo...

Abstract Background Nausea is a common and distressing symptom in palliative care, substantially impairing quality of life. Despite guideline-based antiemetic therapy, a considerable proportion of patients continue to ex...

Abstract Background The antibiotic resistance of Klebsiella pneumoniae poses significant challenges in veterinary clinical settings and threatens poultry production. Veterinarians often employ combination therapy to addr...

BackgroundChronic low back pain (CLBP), with or without radicular pain (RP), is a major cause of disability and reduced quality of life. Psychological comorbidities such as depression, anxiety, and chronic pain disorder ...

ABSTRACT This case report describes the outcome of treatment of dogs with advanced (deeply invasive) nasal planum squamous cell carcinomas with palliative or definitive radiation therapy. All dogs were diagnosed with nas...

Abstract Breast cancer remains one of the most prevalent malignant tumors affecting women worldwide and continues posing a major threat to global health. Current clinical treatments include surgery, chemotherapy, radioth...

Background and purpose: Oesophageal radiotherapy may cause side effects due to high organs of interest (OOIs) doses. While proton therapy (PT) reduces OOI dose compared to photon therapy, setup robustness settings used m...