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Burn injuries represent a major public health concern worldwide, with a disproportionately high burden observed in developing nations. The healing of second-degree burns engages a series of intricate cellular and molecul...

The study investigated the regenerative potential of a water-salt extract of the medicinal leech Hirudo verbana in excisional skin wounds of rats, focusing on its influence on hair follicle restoration. Sixty male rats w...

BackgroundNon-tuberculous mycobacteria (NTM) infections are increasingly recognized in clinical practice, yet diagnosis remains challenging.Case presentationA 52-years-old immunocompetent male developed chronic finger in...

Actinomyces odontolyticus is an uncommon cause of soft tissue infection and is usually regarded as a commensal microorganism of the oropharyngeal and gastrointestinal microbiota. This article reports the first documented...

After tooth extraction, dentists always place sterile tampons on the extracted socket to stop bleeding, to prevent infection and to reduce patients’ discomfort. Ozone is a biocompatible, bactericidal gas that can accel...

Inflamasi merupakan respon alami tubuh terhadap adanya kerusakan jaringan. Salah satu medikamen untuk mengatasi inflamasi adalah antiinflamasi non steroid (AINS). Penggunaan AINS mempunyai beberapa efek samping dan dalam...

BackgroundUlceration is a common complication of infantile hemangioma, and its management poses unique difficulties when the lesion is located in high-risk areas like the scrotum. This case report details the successful ...

IntroductionThe secretome derived from Mesenchymal Stem Cells (MSCs) have received significant attention as a promising tool in regenerative medicine. This “cell-free” strategy offers a promising alternative to stem ...

ABSTRACT Diabetic wound healing is often hindered by poor outcomes, prolonged recovery, and high recurrence. To address this, a new therapy approach was demonstrated in this study, in which ginsenoside (GS) molecules are...

Background: Fractures of the proximal third of the tibia commonly result from high-velocity trauma, particularly road traffic accidents, and are often associated with significant soft-tissue injury. Their management rema...

Introduction Fractures, the most common type of trauma, can cause considerable distress to patients. Pain can not only affect the comfort of fracture patients but also delay their participation in rehabilitation training...

Liver fibrosis is the excessive accumulation of extracellular matrix proteins, primarily collagen, in response to liver injury caused by chronic liver diseases. HIV infection accelerates the progression of liver fibrosis...

Lipopolysaccharide (LPS) triggers signal transduction in dental pulp cells (DPCs), leading to various biological events. The present study described the biological response of DPCs to LPS, aiming to provide a deeper unde...

Background23-Hydroxybetulinic acid (23-HBA), a key bioactive compound in the traditional Chinese herb Pulsatilla chinensis, has garnered substantial scientific interest due to its potent antitumor activity. However, the ...

The nuclear factor kappa light-chain enhancer of activated B cells (NFKB1) pathway is a central regulator of inflammatory gene expression. NFKB1 haploinsufficiency can present with common variable immunodeficiency (CVID)...

Huangjing (Polygonati Rhizoma) is an important medicinal and edible herb, which can be taken orally, brewed in tea, steeped in wine, or used in food processing.The fibrous roots of Polygonum cyrtonema, usually discarded ...

Gingivitis is the second most common disease that occurs in the oral cavity. The use of chlorhexidine as a gingivitis therapy agent has some side effects such as allergic reactions and bacterial resistance. Jasminum Samb...

ABSTRACT Trauma or disease inflicted by tissue injuries may cause tissue degeneration. The use of biomaterials for direct or indirect repair has emerged as a promising alternative, and has become an important research to...

In cases of pulp necrosis, infection products can spread into the periapical tissues, triggering an inflammatory response that stimulates the proliferation of the epithelial cell rests of Malassez. As the epithelial mass...

Abstract Bone defects resulting from trauma, tumors, or infection continue to pose significant clinical challenges, particularly when the defect size exceeds the capacity for spontaneous healing. In this study, we fabric...

Abstract Background Cervicovaginal microbiota dysbiosis has been implicated in the progression of cervical cancer. Recent studies have reported an increased abundance of Porphyromonas species in the vaginal microbiota of...

ABSTRACT Background and Aim Tonsillectomy is one of the most commonly performed surgical procedures on children. Indications for tonsillectomy include recurrent tonsillitis, obstructive sleep apnea, and peritonsillar abs...

Chemokine network is central to the innate and adaptive immunity and entails a variety of proteins and membrane receptors that control physiological processes such as wound healing, angiogenesis, embryo growth and develo...