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Niosomes have been reported as a possible approach to improve the low skin penetration and bioavailability characteristics shown by conventional topical vehicle for Baclofen (centrally acting skeletal muscle relaxant)....

Non-irritant, non-comedogenic and non-polar emollients were pre-selected for determinations of relative dielectric permittivity and solubility of benzoyl peroxide (BP). Those solvents capable of solubilizing BP in concen...

Background: The growth of a topical vehicle microemulsions has been more enhanced compared to the normal skin applications such as creams, gels among others. These micro-structured vehicles showed enhanced solubilization...

Acne vulgaris is a common disease of adolescence that occurs in approximately80% of the population aged 11-30 years. The disease greatlyreduces well-being and self-esteem. In the pathogenesis of acne vulgarismany factors...

ABSTRACT This study aimed to evaluate whether the use of trometamol ketorolac for 30 consecutive days may change the blood count, the serum biochemistry profile, and the urinalysis of healthy dogs. Eleven small breed dog...

Materias / palabras clave: topical treatment; extramammary paget disease; imiquimod

Topicality of comparative study in Foreign Direct Investments (FDI) is determined by the need to deepen analysis of economic activity challenges and opportunities related to cross-border investments. Research in FDI tren...

Abstract This study provides a bibliometric overview of the first decade of the Journal of Big Data (JBD) since its launch in 2014. Using bibliographic records for 1,023 articles and reviews indexed in Scopus (2014–202...

The complex etiology and short-term positive effects of treatments for osteoarthritis (OA) remain a significant challenge globally. The lack of approved disease-modifying OA drugs (DMOADs) and the rapid clearance of intr...

Hand eczema is a common skin disorder with significant functional and economic impacts. Conventional therapy options, such as topical corticosteroids, calcineurin inhibitors, phototherapy and systemic immunosuppressants,...

Aim of the study: In this study the anti-inflammatory activity of aqueous, dichloromethane (CH2Cl2) and methanolic (MeOH) extracts and two major compounds isolated from Lithrea molleoides (Vell.) Engl. (Anacardiaceae) we...

Abstract Despite the extensive use of synthetic and semi-synthetic lipids in nanostructured lipid carrier (NLC) systems, the utilization of Shorea spp. (Illipe butter or tengkawang fat), an indigenous natural solid lipid...

BackgroundSevere alopecia areata in children is difficult to treat, and conventional therapies often show limited efficacy and substantial adverse effects. Dupilumab has shown potential in patients with alopecia areata a...

‘To mention Europe’s Christian roots implies indicating as well the residual sources of moral orientation, which is a factor of Europe's identity.’ [Joseph Ratzinger, Europe’s Crisis of Culture] This study will a...

Introduction: Low-voltage electrical injuries are generally considered low risk but can cause significant thermal injury when current is concentrated through conductive materials. Circumferential neck burns from mobile p...

IntroductionAtopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by immune dysregulation, impaired epidermal barrier function, and recurrent episodes of itching and inflammation. Emerging evidence...

Abstract Background Tympanostomy tubes are used for persistent or recurrent otitis media but are often complicated by otorrhea (25–75%). Treatment relies on culture-guided topical and/or systemic antibiotics, though bi...

Jianghua Hu,1,2,* Shanhong Sun,3,* Kun Gao,4 Jianqing Deng,5 Penglong Yu1 1College of Traditional Chinese Medicine, Chongqing Three Gorges Medical College, Chongqing, People’s Republic of China; 2Depart...

Abstract Background Sjögren’s disease is a systemic autoimmune disease characterized by dysfunction of the salivary and lacrimal glands, leading to xerostomia and xerophthalmia. Case presentation A 55-year-old Hispani...

The Effect of topical application pandan extract gel on gingival wound. Post-gingivectomy wound is usually covered by periodontal dressing, which generally contains some chemical compounds to protect the wound. However, ...

ABSTRACT This study aimed to determine the effectiveness of topical HoofCare® in the treatment of digital dermatitis (DD) in dairy cows. Thirty-six high-yielding Holstein cows with DD in at least one limb were included ...

Abstract Mites of the species Lynxacarus radovskyi, which are commonly found on domestic cats in Brazil, can cause discomfort, itching, and alopecia. The development of new, safer and more effective treatments with a bro...

Abstract Background Diabetic Foot Ulcers (DFUs) represent a global healthcare challenge, imposing substantial socioeconomic burdens due to their increasing incidence and associated mortality. This study evaluates the eff...

Abstract Background Borrelia burgdorferi and Anaplasma phagocytophilum are transmitted by Ixodes spp., with antibodies having been detected in cats in endemic areas. The combination of selamectin plus sarolaner (Revoluti...