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106 resultados encontrados.

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npj Vaccines
Artículo
Acceso abierto Artículo DOAJ
Nature Portfolio; United Kingdom · ISSN 2059-0105
Materias / palabras clave: oncology vaccines, aids vaccine, vaccine safety, vaccine formulation, vaccine adjuvants, veterinary vaccines; Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy; Medicine: Intern...
Idioma English
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Open Access
Adolescent receptiveness to dentist involvement in COVID-19 and HPV vaccination
Artículo
Acceso abierto Artículo DOAJ
Ge Angelina Yueyang et al · De Gruyter · 2025 · ISSN 2191-0278
Human papillomavirus (HPV) and COVID-19 can be prevented and mitigated by vaccines. Few studies have focused on dentists’ role in vaccine decision making, and even fewer have explored adolescent perspectives; a target ...
LCC LCC:MedicineIdioma eng
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Open Access
Bivalent mRNA booster encoding virus-like particles elicits potent polyclass receptor-binding domain antibodies in pre-vaccinated mice
Artículo
Acceso abierto Artículo DOAJ
Chengcheng Fan et al · eLife Sciences Publications Ltd · 2026 · ISSN 2050-084X
mRNA vaccines emerged as a leading vaccine technology during the COVID-19 pandemic. However, their sustained protective efficacies were limited by relatively short-lived antibody responses and the emergence of SARS-CoV-2...
LCC LCC:Medicine; TENDOlNjaWVuY2U~; LCC:Biology (General)Idioma eng
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Open Access
Changes in childhood vaccine hesitancy during the COVID-19 pandemic: a retrospective study based on data from Turkey
Artículo
Material complementario disponible Artículo DOAJ
Seda Özmen Sever et al · BMC · 2026 · ISSN 1824-7288
Abstract Background Vaccine refusal is a growing public health concern, threatening herd immunity and the control of vaccine-preventable diseases. The COVID-19 pandemic has influenced healthcare delivery and vaccine refu...
LCC TENDOlBlZGlhdHJpY3M~Idioma eng
Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.
Material complementario
Development of an adjuvanted, higher-dose, cell-based influenza vaccine: combining advanced technologies to improve vaccine effectiveness
Artículo
Material complementario disponible Artículo DOAJ
Mansoor Ashraf et al · Taylor & Francis Group · 2026 · ISSN 1476-0584
Introduction Influenza remains a significant public health burden, particularly for high-risk populations such as older adults and those with chronic diseases. Effectiveness of standard-dose egg-grown influenza vaccines ...
LCC LCC:Internal medicineIdioma eng
Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.
Material complementario
Evaluation of Tissue Tropism and Horizontal Transmission of a Duck Enteritis Virus Vectored Vaccine in One-Day-Old Chicken
Artículo
Material complementario disponible Artículo CONICET Digital
Abdulrahim, Yassin et al · MDPI · 2024 · ISSN 1999-4915
Herpesvirus of turkey (HVT) recombinant vector vaccines are widely used in the poultry industry. However, due to limitations in loading multiple foreign antigens into a single HVT vector, other viral vectors are urgently...
Idioma eng
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Material complementario
Evaluation of the humoral immune response to primary and booster covid-19 vaccination
Artículo
Material complementario disponible Artículo DOAJ
Mozart Julio Tabosa Sales et al · Editora Unijuí · 2026 · ISSN 1676-188X
This study aimed to evaluate the efficacy of the primary and booster vaccination response against COVID-19. This prospective cohort study was conducted in the Archipelago of Fernando de Noronha (Pernambuco, Brazil). A to...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Material complementario
From empirical vaccinology to predictive systems-based vaccine design: multi-omics integration, artificial intelligence, and global equity challenges
Artículo
Acceso abierto Artículo DOAJ
Nicole Simone De Lima Coelho et al · Frontiers Media S.A · 2026 · ISSN 2674-0702
Although vaccination remains one of the most impactful interventions in contemporary public health, with consistent and widely documented reductions in morbidity and mortality, the traditional empirical development of va...
LCC TENDOlBoeXNpb2xvZ3k~Idioma eng
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Open Access
In silico analysis for identification of tick phagotopes selected by phage-displayed libraries Análises in sílico na identificação de fagotopos de carrapatos selecionados por bibliotecas de phage display
Artículo
Acceso abierto Artículo DOAJ
Carlos Roberto Prudencio et al · Colégio Brasileiro de Parasitologia Veterinária · 2009 · ISSN 0103-846X
Phage display techniques have been widely employed to map epitope structures which have served as the basis for developing molecular vaccines. We have applied this technique to map specific epitopes of Rhipicephalus (Boo...
LCC LCC:Animal cultureIdioma eng
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Open Access
Investigating Parental Perception and Intentions Toward COVID‐19 Vaccination for Children in Ras Al Khaimah
Artículo
Material complementario disponible Artículo DOAJ
Mona Gamal Mohamed et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background Vaccination is a cornerstone of public health, critical for achieving population immunity and protecting against infectious diseases. During the COVID‐19 pandemic, understanding parental perspective...
LCC LCC:MedicineIdioma eng
Material complementario disponibleEl enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.
Material complementario
Navigating vaccine access, trust, coercion and regret: post-pandemic lessons on COVID-19 vaccination among newcomer communities in Alberta, Canada
Artículo
Acceso abierto Artículo DOAJ
Minnella Antonio et al · BMC · 2026 · ISSN 1471-2458
Abstract Background Since the COVID-19 pandemic routine vaccination rates have dropped in Canada. Many newcomers and refugees experience significant vaccine inequities despite wide vaccine availability and COVID-19 pande...
LCC LCC:Public aspects of medicineIdioma eng
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Open Access
Newcastle Disease Vaccination using Mucoadhesive and Conventional Oral Delivery in Commercial Broilers: Serological, Heterophil: Lymphocyte ratio and Lymphoid Histopathological Changes
Artículo
Acceso abierto Artículo DOAJ
Olawale Ola et al · Atatürk University · 2026 · ISSN 2822-3608
Newcastle Disease (ND) threatens poultry productivity worldwide. Vaccination remains central to control, but conventional oral delivery often yields short-lived immunity. Mucoadhesive systems are an alternative delivery ...
LCC TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Open Access
Active Surveillance for COVID-19 Vaccine Safety Using Sequential Analysis in Korea: Population-Based Retrospective Observational Study
Artículo
Acceso abierto Artículo DOAJ
Na-Young Jeong et al · JMIR Publications · 2026 · ISSN 2369-2960
Abstract BackgroundWith the advent of new vaccines, including the COVID-19 vaccines introduced during the recent pandemic, the need for near real-time active surveillance has increased to support timely regul...
LCC LCC:Public aspects of medicineIdioma eng
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Open Access
Anti-trypanosomal, anti-inflammatory, and neuroprotective effects of Cichorium intybus sesquiterpene lactones in experimental Trypanosoma evansi infection
Artículo
Material complementario disponible Artículo DOAJ
Marian G. Sawerus et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Trypanosoma evansi is an important protozoan pathogen affecting various animal species particularly camels and horses, leading to significant economic losses. The ineffective control of T. evansi is attributed t...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Material complementario
Assessment of the acid phosphatase CP01850 from Corynebacterium pseudotuberculosis in DNA and subunit vaccine formulations against caseous lymphadenitis
Artículo
Acceso abierto Artículo DOAJ
A.F.S. Rezende et al · Universidade Federal de Minas Gerais, Escola de Veterinária · ISSN 1678-4162
ABSTRACT The target cp1002_RS01850 from Corynebacterium pseudotuberculosis was used to construct a DNA and recombinant subunit vaccine against caseous lymphadenitis. Recombinant protein rCP01850 was expressed in Escheric...
LCC LCC:Animal cultureIdioma eng
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Open Access
Augmented immunogenicity of the HPV16 DNA vaccine via dual adjuvant approach: integration of CpG ODN into plasmid backbone and co-administration with IL-28B gene adjuvant
Artículo
Acceso abierto Artículo DOAJ
Yan Zhou et al · BMC · 2025 · ISSN 1743-422X
Abstract Therapeutic human papillomavirus (HPV) DNA vaccine is an attractive option to control existed HPV infection and related lesions. The two early viral oncoproteins, E6 and E7, are continuously expressed in most HP...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Open Access
Biological valorization of methane and nitrogen gas-derived ammonia via methanotrophic bacteria for gut-beneficial nutrients
Artículo
Acceso abierto Artículo DOAJ
Zixi Gao et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract The in-situ upcycling of decentralized methane and nitrogen gas (N2)-derived ammonia via methanotrophic bacteria is highly attractive. However, the toxic intermediate generated from ammonia oxidation significant...
LCC TENDOlNjaWVuY2U~Idioma eng
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Open Access
Bordetella parapertussis survives the innate interaction with human neutrophils by impairing bactericidal trafficking inside the cell through a lipid raft-dependent mechanism mediated by the lipopolysaccharide o antigen
Artículo
Acceso abierto Artículo CONICET Digital
Gorgojo, Juan Pablo et al · American Society for Microbiology · 2012 · ISSN 4309-4316
Whooping cough is a reemerging disease caused by two closely related pathogens, Bordetella pertussis and Bordetella parapertussis. The incidence of B. parapertussis in whooping cough cases has been increasing since the i...
Idioma eng
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Open Access
COVID-19 vaccine immunogenicity in Mongolian adults with and without chronic hepatitis
Artículo
Material complementario disponible Artículo DOAJ
Viviane Callier et al · BMC · 2026 · ISSN 1471-2334
Abstract Background Mongolia has a high prevalence of liver disease from chronic viral hepatitis infections, which can compromise the immune response. It is unclear whether people with chronic liver disease produce a rob...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Material complementario
Cell-type differential targeting of TLR5 and TLR7 agonists and their synergistic effect as nasal mucosal adjuvants
Tesis
Acceso abierto Tesis DOAJ
ZHUO Kexing et al · Editorial Office of Journal of Army Medical University · 2026 · ISSN 2097-0927
Abstract Objective To compare the differential activation characteristics of Toll-like receptor 5 (TLR5) agonist KFD and Toll-like receptor 7 (TLR7) agonist R837 on nasal epithelial cells (NECs) and bone marrow-derive...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma zho
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Open Access
Coronavirus Disease 2019 Vaccination for Cancer Patients: Risk or Benefit?
Artículo
Acceso abierto Artículo DOAJ
Bruno Eduardo Pereira Laporte et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2022 · ISSN 0100-7203
Abstract Objective The aim of the present study is to list the published clinical trials on coronavirus disease 2019 (COVID-19) vaccines, to describe the mechanism of action of the identified vaccines, and to identify p...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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Open Access
Deciphering the role of glycolipids as emerging therapeutic targets in EMT-driven cancer progression
Artículo
Acceso abierto Artículo DOAJ
Arpita Mukherjee et al · Springer · 2026 · ISSN 2730-6011
Abstract Epithelial-to-mesenchymal transition (EMT) is a complex and dynamic cellular process during which epithelial cells lose their polarity and cell adhesion capabilities and subsequently express mesenchymal stem cel...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Open Access
Defining the determinants of protection against SARS-CoV-2 infection and viral control in a dose-down Ad26.CoV2.S vaccine study in nonhuman primates.
Artículo
Acceso abierto Artículo DOAJ
Daniel Y Zhu et al · Public Library of Science (PLoS) · 2022 · ISSN 1544-9173
Despite the rapid creation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) vaccines, the precise correlates of immunity against severe Coronavirus Disease 2019 (COVID-19) are still unknown. Neutralizing a...
LCC LCC:Biology (General)Idioma eng
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Open Access
Development of a Prophylactic mRNA Vaccine for Severe Fever with Thrombocytopenia Syndrome Using HSA based LNP
Artículo
Acceso abierto Artículo DOAJ
Tsenddari Ganbold et al · Nature Portfolio · 2026 · ISSN 2059-0105
Abstract Current lipid nanoparticles (LNPs) used in mRNA vaccines typically incorporate polyethylene glycol (PEG) as a stabilizing material; however, safety concerns have prompted the search for non-PEG alternatives. Sev...
LCC LCC:Immunologic diseases. Allergy; TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbIdioma eng
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Open Access