Buscar recursos académicos

IntroductionChronic spontaneous urticaria (CSU) is a clinical diagnosis managed according to American Academy of Allergy, Asthma & Immunology (AAAAI) and the American College of Allergy, Asthma & Immunology (ACAAI) guide...

ABSTRACT Background/Aim Most patients with proteinuria are considered to have typical diabetic nephropathy (DN). However, when proteinuria occurs without diabetic retinopathy, with hematuria, or persists despite strict g...

Objective This study aimed to describe the clinical and neuroimaging characteristics and 120-day outcomes in neuropsychiatric systemic lupus erythematosus patients. Methods This prospective study involved 32 patients wit...

Abstract Background Understanding of equine herpesvirus‐1 (EHV‐1) myeloencephalopathy (EHM) is complicated by disparities among studies. Objective Compare clinical findings and outcome in horses involved in 2 recent ...

Highest prevalence of all antineutrophil cytoplasmic antibody associated systemic vasculitides is the Wegener granulomatosis, and it’s typically characterized by a necrotizing granulomatous vasculitis of the respirator...

Henoch-Schönlein purpura (HSP) is a vasculitis characterized by purpuric rash, arthritis, nephritis and gastrointestinal symptoms and it is generally seen in children. We report here a case of crescentic HSP nephritis w...

Microscopic polyangiitis is small vessel necrotizing vasculitis involving the kidney, sometimes skin, and lung. This disease is characterized by the presence of an ANCA and few or no immune deposits in involved vessels. ...

Abstract Background Dynamics of infection by Bartonella and Rickettsia species, which are epidemiologically associated in dogs, have not been explored in a controlled setting. Objectives Describe an outbreak investigatio...

Deficiency of adenosine deaminase 2 (DADA2) was identified in 2014 as a novel inborn error of immunity caused by biallelic pathogenic variants in ADA2. DADA2 patients express two predominant clinical phenotypes: (1) auto...

Genetic alteration of the genes of cytoskeletal regulatory proteins (e.g., actin-related protein complex-1 [ARPC1]) results in severe immune and hematological defects. ARPC1B deficiency (ARPC1BD) is an immune-actinopathy...

Behcet's disease (BD) is a systemic chronic vasculitis of unknown aetiology characterised by mainly oro-genital ulcers. Renal involvement in BD is seen much less frequently than one would expect in a systemic vasculitis....

Wegener's Granulomatosis (WG) is characterized by necrotizing granulomatous lesions of the respiratory tract, glomerulonephritis and frequently vasculitis involving other organs. We reported the different features of WG ...

Abstract Background Kawasaki disease (KD) is an acute systemic vasculitis of childhood and the leading cause of acquired heart disease in children in developed countries. Infants frequently present with incomplete diseas...

BackgroundGATA2 deficiency results from heterozygous pathogenic variants in the GATA2 gene, which encodes a zinc-finger transcription factor essential for hematopoietic stem and progenitor cell development. It is a highl...

OBJETIVO: Avaliar a influência das complicações maternas, da prematuridade, dos parâmetros antropométricos do feto e de condições do recém-nascido nos diferentes graus de corioamnionite. MÉTODOS: Foram analisada...

Abstract Background Equine herpesvirus myeloencephalopathy (EHM) has severe impact on the sport horse population. Objective Study the influence of EHM on the likelihood of affected horses to return to their previous perf...

The complement system is a mediator and marker of renal damage. There are three pathways of complement activation: classical, alternative and lectin pathway. Lectin pathway is initiated by binding of mannose-binding lect...

Metformin is the most widely used oral antidiabetic drug in the world. It is the first-line drug in type 2 diabetes, where its inhibiting effect on hepatic glucose production, increasing muscle and adipose tissue insulin...

Microscopic polyangiitis nodosa (MPA) is a necrotizing vasculitis that affects small vessels, typically associated with myeloperoxidase anti-neutrophil cytoplasmic antibody. Cerebrovascular diseases are rarely reported t...

Henoch-Schönlein purpura (HSP), characterized by non-thrombocytopenic purpura accompanied by arthritis/arthralgia, gastrointestinal and genitourinary system involvement is the most common vasculitis in childhood. Associ...

IntroductionPolyarteritis nodosa (PAN) is a rare systemic necrotizing vasculitis affecting medium-sized vessels. While peripheral neuropathy occurs in 50–75% of patients, cranial nerve involvement is exceptionally rare...

Polycythemia vera (PV) is a JAK2-mutated myeloproliferative neoplasm associated with thrombotic and vascular complications. Giant cell arteritis (GCA) is a granulomatous large-vessel vasculitis that may involve the aorta...

Wegener’s granulomatosis (WG) is a disorder that causes necrotizing granulomatosis vasculitis particularly of the upper respiratory tract, lung and kidney. A 43-year-old male who had been treated with hemodialysis beca...

BackgroundBehçet’s disease is a multisystem inflammatory disorder whose diagnosis can be challenging due to overlapping features with other inflammatory conditions and primary immunodeficiencies (1). In patients with ...