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Objective. To evaluate the relationship between ophthalmic hemodynamic parameters, particularly the rheographic coefficient (RQ), and the activity of iris neovascularization in neovascular glaucoma (NVG) of different eti...

Objective: To compare clinical and structural outcomes of combination therapy (anti-VEGF + PDT) versus anti-VEGF monotherapy in patients with pachychoroid neovasculopathy (PNV) during 12-month follow-up. Materials and Me...

Abstract Cisplatin (CISP) is a platinum-based chemotherapeutic drugs that are commonly used to treat several types of cancers. However, its clinical application faces several hurdles that could limit its clinical efficie...

Se analizan los aspectos fundamentales de la anatomía y fisiología de la visión humana, particularmente las células fotorreceptoras (conos y bastones), sus características y distribución en la retina. Especial ate...

Abstract Background Duchenne muscular dystrophy (DMD) results from mutations in the DMD gene, which differentially affect dystrophin isoforms (Dp427, Dp260, Dp140, Dp71) expressed in distinct brain and retinal cell types...

ABSTRACT The aim of this study was to establish normal baseline ERG values of 23 anesthetized deer belonging to 8 neotropical species (Mazama americana, Mazama nemorivaga, Mazama gouazoubira, Mazama nana, Mazama bororo, ...

ObjectiveIn the present study, we established a rat model of optic nerve injury to evaluate whether direct local delivery of neurotrophic agents following traumatic optic neuropathy (TON) enhances retinal ganglion cells ...

The activity and survival of retinal photoreceptors depend on support functions performed by the retinal pigment epithelium (RPE) and on oxygen and nutrients delivered by blood vessels in the underlying choroid. By combi...

The ‘uveitis masquerade syndrome’ is a large group of neoplastic and non-neoplastic conditions that mimic and are initially misdiagnosed as uveitis. These eye diseases account for approximately 5% of all presentation...

Purpose. We present a case series of retinitis pigmentosa associated with uveitis and share our clinical observations and insights on this co-occurrence. Materials and methods. This prospective, non-controlled case seri...

Las complicaciones obstétricas y entre ellas la asfixia perinatal (AP), son causa de lesiones retinianas, como la retinopatía proliferativa isquémica, que incluye a la retinopatía del prematuro (ROP). Hasta hoy no ex...

Background: Numerous studies have been conducted to examine the growth factors capable of exerting simultaneous effects on the vascular and metabolic components of the pathogenesis of diabetic retinopathy (DR). Purpose: ...

A new fluorescent sensor makes it possible to track the neurotransmitter GABA in freely moving animals.

With a purely optical modulation of fluorescent behaviors, stimulated emission depletion (STED) microscopy allows for far-field imaging with a diffraction-unlimited resolution in theory. The performance of STED microscop...

ABSTRACT Background and Aim Non‐adherence to diabetes medication treatment is a recognized public health problem that can lead to unfavorable clinical, humanistic, and economic outcomes. This study aimed to analyze adh...

BackgroundPhakic intraocular lenses (pIOLs), used to correct high refractive errors, have since been associated with long-term complications including glaucoma and cataract formation. Elevated intraocular pressure (IOP) ...

Diabetic retinopathy (DR) is one of the leading causes of preventable blindness worldwide, making timely and accurate detection crucial for effective management. This study introduces DR-NetFusion, a novel hybrid deep le...

Abstract Purpose To critically evaluate evidence supporting the angiogenesis-inflammation hypothesis in diabetic retinopathy (DR); to examine the roles of angiogenic growth factors and inflammatory cytokines in the bipha...

Artificial intelligence (AI) has emerged as a transformative force in modern ophthalmology, enabling rapid advances in disease detection, clinical decision support, workflow optimization, and tele-ophthalmology. Ophthalm...

IntroductionVisual electrophysiology, including electroretinograms (ERG) and visual evoked potentials (VEP), provides a real-time functional assessment of retinal and post-retinal pathways, complementing structural imagi...

BackgroundThis study examined the association between vitreous cellular repressor of E1A-stimulated genes 1 (CREG1) levels and the therapeutic response to ranibizumab in patients with diabetic macular edema (DME).Methods...

By color-converting the violet laser diode (VLD) with a cadmium selenide and zinc sulfide (CdSe/ZnS) core-shell-quantum dot (QD) doped polydimethylsiloxane (PDMS) film, the VLD + CdSe/ZnS core-shell-QD transferred wh...

Background: Diabetic retinopathy (DR) is a major cause of blindness in working-age individuals in the developed countries. Studies have found that diabetic macular edema (DME) is a major cause of visual impairment in pat...

In this paper, we design a multimodal visible/near-infrared photoacoustic microscopy and optical coherence tomography (VIS/NIR-PAM-OCT) system for imaging both retina and retinal pigment epithelium (RPE)/choroid complex ...