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BackgroundFrailty is significantly more prevalent in individuals with Parkinson’s disease (PD) than in general population, yet the underlying neuropathophysiological mechanisms remain poorly understood. This study aime...

Objective This study aimed to explore the influence of the angiotensin-(1–7)/Mas receptor and angiotensin II/angiotensin II type 1 receptor pathways on pyroptosis during sepsis and their subsequent effects on cognitive...

Abstract Background This letter engages with the seminal review by Argyrakopoulou et al. Obesity and the Gut-Brain Axis in Type 1 Diabetes Mellitus: Terra Incognita? Curr Obes Rep, https://doi.org/10.1007/s13679-025-0065...

"Local Field Potentials (LFPs) are easy to access electrical signals of the brain that represent the summation in the extracellular space, of currents originated within the neurons. As such, LFPs could contain infor mati...

Abstract Cisplatin (CISP) is a platinum-based chemotherapeutic drugs that are commonly used to treat several types of cancers. However, its clinical application faces several hurdles that could limit its clinical efficie...

Abstract Significant changes occur in brain structure and cognition during adolescence. Investigating their association can provide insight into brain-based cognitive development, yet previous studies are limited by narr...

Abstract The advancement and development of medical surgical robots have provided new technological support for brain surgery and neurosurgical procedures, improving the reliability of highly complex and precise surgerie...

The brain exhibits a wide variety of spatiotemporal patterns of neuronal activity recorded using functional magnetic resonance imaging as the so-called blood-oxygenated-level–dependent (BOLD) signal. An active area of ...

Frontal and parietal regions are associated with some of the most complex cognitive functions,and several frontoparietal resting state networks can be observed in wakefulness. We used functional magnetic resonance imagin...

Brain expression of the enzyme P450-aromatase has been studied extensively. Subsequent to the aromatisation hypothesis having established brain aromatase as a key factor to convert gonadal testosterone to oestradiol, sev...

Background. The significant increase in the number of patients with arterial hypertension both worldwide and in our country necessitates a more detailed study of the pathogenetic features of changes that occur in target ...

Abstract Half of all newborn neurons in the developing brain are removed via efferocytosis - the phagocytic clearance of apoptotic cells. Microglia are brain-resident professional phagocytes that play important roles in ...

Abstract Objective The study aimed to evaluate the hypoxia-induced brain injury and neuroprotective effects of pyrimidine and its derivative, arylvinylpyrimidine (AVP), in the freshwater catfish, Heteropneustes fossilis....

Abstract Mild traumatic brain injury (mTBI) disproportionately affects children and adolescents and has been associated with poorer neurocognitive performance, but the biological mechanisms driving symptom variability an...

Abstract Limited studies have evaluated the influence of redox-related metals on the Alzheimer´s brain. We determined 15 metals in 241 human brain samples obtained from five biobanks. We examined the levels of metals in...

Alcohol consumption, in particular ethanol (EtOH), typically begins in human adolescence, often in a “binge like” manner. However, although EtOH abuse has a high prevalence at this stage, the effects of exposure duri...

Sharon Wang-Price,1 Jason Zafereo,2 Khalid Alkhathami,3,* Yousef Alshehre,4,* Hui-Ting Goh1 1School of Physical Therapy, College of Health Sciences, Texas Woman’s University, Dallas, TX, USA; 2Departmen...

We present the case of a 50-year-old man with a history of rheumatoid arthritis, chronic bronchitis, with a history of multiple lung infections, including Mycobacterium avium complex and Aspergillus terreus starting in h...

En el presente informe se detalla un trabajo de desarrollo tecnológico, en el que se presenta el diseño e implementación de un software colaborativo que da soporte a la técnica de Brainstorming. Inicialmente, se pre...

We studied if monocrotaline (MCT) portal hypertensive model modifies blood-brain barrier (BBB) condition. Male Wistar rats were used: Group MCT injected i.p. with MCT (60 mg/kg of body weight) and Group Sham (GS) with sa...

A baseline or control state is fundamental to the understanding of most complex systems. Defining a baseline state in the human brain, arguably our most complex system, poses a particular challenge. Many suspect that lef...

The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with the CDC and NCI, is the largest population-based registry focused exclusively on primary brain and other central nervous system (CNS) ...

An MRI time course of 512 echo-planar images (EPI) in resting human brain obtained every 250 ms reveals fluctuations in signal intensity in each pixel that have a physiologic origin. Regions of the sensorimotor cortex th...

During performance of attention-demanding cognitive tasks, certain regions of the brain routinely increase activity, whereas others routinely decrease activity. In this study, we investigate the extent to which this task...