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ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and...

Metabolic syndrome (MetS) is a cluster of metabolic disturbances increasing a risk of cardiovascular diseases and diabetes 2 types. The main features of MetS include atherogenic dyslipidemia, elevated blood pressure, ins...

The increasing lack and limitations of key cereals such as rice and wheat, aggravated by climate change, growing population, and declining agricultural sustainability, pose significant threats to global food and nutritio...

Abstract Chronic pain is a multifactorial condition often accompanied by comorbidities such as anxiety, depression, and cardiovascular dysfunction. Traditional injury-based models have provided valuable mechanistic insig...

Durante o processo de assimilação e uso dos alimentos, diferentes respostas metabólicas podem ser desenvolvidas pelo organismo dos animais. Estas respostas são fruto da integração de mecanismos complexos, que envol...

Abstract Background The natural history of hypertrophic cardiomyopathy (HCM) in cats has been mainly studied in cats referred for suspected heart disease, which can skew the results towards cats with clinical signs. Few ...

New-onset diabetes mellitus after transplantation (NODAT) is common in kidney recipients, threatening health and longevity by predisposing to microvascular and cardiovascular disease and by reducing graft survival. Sever...

The pandemic of COVID-19 left profound global impacts on public health, economics, and social dynamics. Since its emergence, the virus has spread across 229 countries, infecting over 590 million individuals and causing 7...

Abstract Fetal growth restriction (FGR) occurswhen the fetus does not reach its intrauterine potential for growth and development as a result of compromise in placental function. It is a condition that affects 5 to 10% o...

As a broad-spectrum preservative， sodium dehydroacetate（DHA-S） was once used in a variety of foods. However， with the systematic research on its toxic effects， the potential threats to human health posed by DHA...

Atherosclerosis, driven by elevated cholesterol levels, remains a major risk factor for cardiovascular disease. 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR), the rate-limiting enzyme involved in cholesterol bio...

Cardiovascular disease and diabetic nephropahty account for much of the morbidity and mortality associated with diabetes mellitus. Genotypic abnormalities of the reninangiotensin system have been suggested as a risk fact...

Ergot alkaloids are a type of alkaloids secondary metabolic produced by Claviceps or Epichloë spp infected with black barley， wheat， rye， rice， corn， oats， and various other gramineous plants. Long-term expo...

Herbal medicines have been extensively used for centuries owing to their therapeutic benefits and comparatively low incidence of adverse effects. Despite their clinical potential, the effectiveness of many herbal formula...

Lipid abnormalities contribute to the increase in cardiovascular morbidity and mortality in chronic renal failure (CFR) patients with or without dialysis. Lipoprotein (a) and, a unique lipoprotein has been shown to be an...

OBJECTIVE: Apelin-13 is a biomarker that was shown to be related to cardiovascular disease risk in peritoneal dialysis patients. The aim of our study was to investigate the association of serum apelin-13 levels with infl...

Background: Outer membrane vesicles (OMVs) from Gram-negative bacteria are spherical lipid bilayer nanostructures with diameters of 20 to 250 nm. Porphyromonas gingivalis (P. gingivalis), a keystone periodontal pathogen,...

Cardiovascular disease based mortality levels in hemodialysis (HD) patients are high. The objective in this study was to investigate the relationship among traditional and newly described risk factors and carotid artery ...

AIM: Cardiovascular diseases are the leading cause of morbidity and mortality in chronic kidney disease (CKD). Inflammation and endothelial dysfunction contribute to the development of cardiovascular disease in CKD. Pent...

The purpose of the review is to analyze the results of scientific research on the effect of antioxidant activity of potatoes on human health, to consider modern approaches to breeding potato with high antioxidant activit...

Jacklyn Yosefin Gracia Lubis, Artha Falentin Putri Susilo, Ruswana Anwar, Anita Rachmawati Obstetrics and Gynecology Department, Faculty of Medicine, Padjadjaran University – Dr. Hasan Sadikin General Hospital, Bandung...

Background/Aims: Myocardial stretch increases cardiac force in two consecutive phases: The first one due to Frank-Starling mechanism, followed by the gradually developed slow force response (SFR). The latter is the mecha...

Abstract The core pathological mechanisms of diabetic microvascular diseases, such as nephropathy, diabetic retinopathy (DR), and neuropathy, involve the dysfunction and loss of microvascular endothelial cells (ECs), vas...

Introdução As doenças cérebro-cardiovasculares necessitam de um acompanhamento regular e especializado, onde se inclui as patologias que necessitam de anticoagulantes orais, com o intuito de diminuir os internament...