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Hyaluronan (HA) modulates multidrug resistance (MDR) as well as cell migration. Tiam1 is involved in cytoskeleton reorganization during tumor invasion. In this report we show the relationship among HA, Tiam1, migration a...

FtsZ is a tubulin homolog in bacteria. It forms a Z-ring to recruit other proteins in the process of cell division through its GTPase activity. Amino acid sequence of FtsZ was obtained from uniprot database and used for ...

Abstract Helicobacter pylori is a bacterium that naturally thrives in acidic environments and has the potential to induce various gastrointestinal disorders in humans. The antibiotic therapy utilized for treating H. pylo...

Abstract Probiotics are currently considered as one of tools to modulate immune responses under specific clinical conditions. The purpose of this study was to evaluate whether oral administration of three different probi...

Asymptomatic malaria infections may affect red blood cell (RBC) homeostasis. Reports indicate a role for chronic hemolysis and splenomegaly, however, the underlying processes are incompletely understood. New hematology a...

Abstract Since the first report in 1972, several studies have documented an association between Parkinson’s disease (PD) and melanoma. Up to 20-fold increased risk of melanoma was reported in PD patients, while a perso...

Here, we identify a novel signaling pathway in which Rnd3 regulates the metastatic potential of lung cancer cells. Understanding this pathway could be leveraged to target metastatic disease. Rnd3 regulates cellular proce...

Accurate RNA quantification at the single-cell level is critical for understanding the dynamics of gene expression and regulation across space and time. Single molecule FISH (smFISH), such as RNAscope, provides spatial a...

Hailing Pan,1,* Zixin Huang,2,* Aiping Li,1 Meiya Li,3 Yanxing Li,1 Ya Lin,1 Jiayin Cai1 1Department of Oncology, Traditional Chinese Medical Hospital of Wenling Affiliated to Zhejiang Chinese Medical Uni...

ABSTRACT Background Skin cancer is one of the most prevalent malignancies worldwide, characterized by the abnormal growth of skin cells and significant clinical challenges. Conventional treatments—including surgery, ch...

Lipid A in the cell wall of  Salmonella typhi and pseudomonas aeruginosa  were extracted and analyzed by the GC/MS technique. Three concentrations were prepared (50, 100, 200) mg/100g of body weight. The sample...

Abstract Meat analogs are a burgeoning industry, with plant-based meat analogs, insect-based meat analogs, algae-based meat analogs, mycoprotein-based meat analogs, and cell-based meat analogs. However, despite the indus...

ABSTRACT Background and Aims Between 200,000 and 300,000 children with sickle cell disease (SCD) are born in Africa every year, with 75%–80% of these children living in sub‐Saharan Africa. In newborns with SCD, signi...

ABSTRACT The bioaccessibility of bioactive compounds in Euterpe spp. fruits influences both their nutritional value and their biological potential. Composition and solubility of bioactive compounds are essential variable...

Abstract Expectations for the industrialization of cultured meat are growing due to the increasing support from various sectors, such as the food industry, animal welfare organizations, and consumers, particularly vegeta...

ABSTRACT Mass cytometry is optimal for acute leukemia immune checkpoint profiling. However, current commercial metal‐chelating polymer (MCP) metal tags limit its sensitivity due to low metal loading capacity. We report...

When polymers are irradiated with heavy ions new chemical groups are created in a few microns of the material. The irradiation changed the polarity and wettability on the surface so that could enhance the biocompatibilit...

Convergent extension (CE) is a fundamental morphogenetic process where oriented cell behaviors lead to polarized extension of diverse tissues. In vertebrates, regulation of CE requires both non-canonical Wnt, its co-rece...

Background: The nature of rejection and fetal allograft survival following the host-versus-graft reactivity remains the subject of intense investigation. Pregnancy-induced hypertension, also known as pre-eclampsia, is a ...

Abstract Rapid population growth and a corresponding increase in the demand for animal-derived proteins have led to food supply challenges and the need for alternative and sustainable meat production methods. Therefore, ...

ABSTRACT Epithelial and endothelial monolayers maintain homeostasis by adapting to physiological stimuli and injury through conversion processes that remain incompletely understood. Using human umbilical vein endothelial...

Abstract Background Apoptosis is a fundamental biological process and a central determinant of therapeutic response in breast cancer (BC). Resistance to immunotherapy is increasingly recognized to be driven, in part, by ...

Jayshree H Ahire,1 Qi Wang,2 Yongping Bao,2 Isabelle SR Storer,1,3 Stefan Bidula,1,3 Gary Rowley,3,4 Jason C Crack1 1School of Chemistry, Pharmacy and Pharmacology, University of East Anglia, Norwich, Norfolk, UK; 2Norwi...

Weiming Hao,1 Ruigao Song,1 Huimin Lv,1 Chunying Song2 1Reproductive Medicine Center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiy...