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ABSTRACT Polyamine oxidase activity in cerebrospinal fluid of normal children was determined, it was found that specific activity of crude PAO 64.16  8.18 enzyme unit/mg protein. Partial purification of the enzyme was...

Abstract Background Non‐suppurative encephalitides in a variety of species, including humans and dogs, have been linked to infection by astroviruses and bornaviruses. Hypothesis/Objectives To determine whether or not r...

Osteoporosis is a very common disease nowadays, and it is mostly seen in postmenopausal women. In postmenopausal women, with the decrease of estrogen, directly or indirectly, it makes the decrease of bone mineral density...

BackgroundMacrophage polarization plays a critical role in shaping the immunosuppressive tumor microenvironment (TME) of prostate cancer (PCa). Tumor-associated macrophages (TAMs), particularly those exhibiting immunoreg...

Abstract Background Eight‐hydroxy‐2′‐deoxyguanosine (8‐OHdG), a biomarker of oxidative damage evaluated in human neurodegenerative disease, has potential to correlate with postmortem diagnosis of neuroaxonal dy...

Abstract Background Osseous‐associated cervical spondylomyelopathy (OA‐CSM) is a common condition of the cervical vertebral column that affects giant dog breeds. MicroRNAs (miRNAs) are small RNAs that regulate gene e...

We are reporting a 14-year-old male who presented at 12 years of age with recurrent episodes of hypothermia and bradycardia (30s) secondary to culture-negative septic shock from presumed viral respiratory illnesses. His ...

IntroductionTrogocytosis is an intracellular transfer of membrane and membrane-associated proteins in a cell–cell contact manner. Trogocytosis plays an important role in immune regulation. We hypothesized that trogocyt...

The diagnosis of bovine herpesvirus 5 (BoHV-5) encephalitis is confirmed after death by laboratory methods applied to brain fragments. Alternative methods to confirm ante-mortem diagnosis are important because the diseas...

BackgroundPrimary diffuse leptomeningeal melanocytosis (PDLM) is a rare central nervous system neoplasm. Diagnosis is challenging in amelanotic variants because they lack the characteristic T1 hyperintensity on magnetic ...

Recurrent polychondritis (RP) is a rare systemic autoimmune disorder that rarely involves the central nervous system (CNS). This report describes a 68-year-old male RP patient who was admitted with bilateral auricular sw...

Abstract Background There exists a scarcity of information on risk factors associated with case outcomes in goats diagnosed with encephalitic listeriosis. Objective Evaluate risk factors associated with outcomes in 36 ca...

Abstract Ventricular shunt catheters are the standard of care for managing hydrocephalus, yet 40% of implanted catheters fail within two years of implantation, mainly due to proximal catheter obstruction. Prior literatur...

Abstract Tumor-associated macrophages (TAMs) are pivotal in the immunosuppressive tumor microenvironment of pancreatic ductal adenocarcinoma (PDAC). The efficacy of targeting the CSF-1/CSF-1R axis in PDAC remains uncerta...

Abstract Cerebrospinal fluid metabolomics is a promising research technology in the elucidation of nervous system disorders. Therefore, in this work, a cerebrospinal fluid (CSF) metabolomics method using liquid chromatog...

Abstract Integrating Industry 4.0 (I4.0) technologies with Lean Six Sigma (LSS) tools holds significant potential for enhancing manufacturing excellence (ME). This paper provides a comprehensive review of 181 research a...

Paraneoplastic syndromes (PNS) are triggered by an altered immune system response to a neoplasm. The symptoms of PNS usually precede malignancy making its diagnosis difficult. They are rarely associated with breast cance...

RESUMO O presente estudo teve como objetivo avaliar o os padrões de fermentação microbiana do ceco de suínos, utilizando-se um modelo aplicado na técnica in vitro de produção de gases para ruminantes. Três tipos ...

Abstract Background Decompressive craniectomy (DC) is always a familiar rescue procedure in refractory intracranial hypertension. However, controversy still exists regarding the best method of dural opening while perform...

The most common cause of death in patients with end-stage renal disease is cardiovascular (CV) disease. Vascular calcifi cation (VC) is a CV risk factor among dialysis patients. Advanced age, dialysis adequacy, vitamin D...

Encephalitis in immunocompromised individuals presents a unique diagnostic and treatment challenge due to the interplay between infection and immune dysregulation.A 48-year-old male with a history of recurrent sinusitis ...

Abstract Background While Canadian First Nations communities actively participate in sport, cultural, and land-based activities, they face various barriers to physical activity. Despite calls for increased support at all...

Tissue classification in Magnetic Resonance (MR) brain images is an important issue in the analysis of several brain dementias. This paper presents a modification of the classical K-means algorithm taking into account th...

El género Pestivirus pertenece a la familia Flaviviridae, la cual también incluye a los géneros Flavivirus y Hepacivirus (Virus de la Hepatitis C). Dentro del género Pestivirus hay cuatro especies reconocidas por el ...