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Background and purpose: Stereotactic radiotherapy (SRT) delivers high doses with submillimeter precision to small targets, requiring accuracy in both dose calculation and delivery. This study aimed to perform a dosimetri...

Cancer therapy and food preservation both face significant challenges related to stability, targeted delivery, safety, and efficiency of active compounds. Biopolymer-based nanoparticles, particularly those derived from c...

PurposeThe COVID-19 pandemic disrupted essential services, posing unique challenges for individuals with Autism Spectrum Disorder (ASD) who depend on consistent, specialized support. Service providers faced unique challe...

Abstract Background Systemic antibiotic administration requires repeated dosing to maintain therapeutic plasma concentrations. Controlled drug delivery systems reduce the need for continuous systemic antibiotic use by en...

Gemini surfactants are amphiphilic molecules formed by two polar heads and two hydrophobic tails joined by a spacer between the polar groups. Their molecular structure gives them particular physico-chemical properties in...

Glioblastoma (GBM) is the most common and aggressive type of central nervous system cancer, characterized by high rates of recurrence and mortality. As the highest-grade glioma, patient prognosis remains poor despite mul...

In the biomedical field, polyethylene glycol-based materials demonstrate remarkable positive potential as drug delivery systems, in wound healing, and tissue engineering. It’s known that complex of polyethylene glycol ...

Various specially designed poly(acrylamide-co-N-isopropylacrylamide) (PAA-NIPA) nanoparticles (NPs) with different acrylamide (AA)/NIPA molar compositions were synthesized by microemulsion polymerization and evaluated as...

ABSTRACT Background Skin cancer is one of the most prevalent malignancies worldwide, characterized by the abnormal growth of skin cells and significant clinical challenges. Conventional treatments—including surgery, ch...

Saliva as a microfluidic system offers numerous advantages for both general and oral health diagnostic and therapeutic procedures since its assembly is quick, stress-free, inexpensive and non-invasive. Moreover, saliva i...

Rapid urbanisation across Africa is placing increasing strain on urban governance systems, intensifying long-standing challenges such as infrastructure deficits, inefficient service delivery, and limited institutional ca...

IntroductionThe integration of tuberculosis (TB) preventive treatment (TPT) into HIV services through electronic health records (EHR) can improve outcomes by enhancing care coordination, reducing redundancies, and suppor...

IntroductionIntestinal ischemia-reperfusion (I/R) injury, a common and severe clinical condition with high morbidity and mortality, burdens healthcare systems. Our previous investigations established that a nano-delivery...

La integración entre biotecnología y nanotecnología conforma la bionanotecnología que es una disciplina que permite potenciar la utilización de biomoléculas con materiales abióticos de diseño a escala nanométric...

The aim of this study was to clarify the current situation and challenges of community-based rehabilitation (CBR) in depopulated areas from the perspective of physicians and to develop a model suited to such contexts. Se...

BackgroundThe growing global population of older adults presents significant challenges for health and social care systems, requiring effective quality improvement (QI) interventions to enhance care delivery and outcomes...

IntroductionAntimicrobial resistance (AMR) is rising globally, particularly among the clinically important ESKAPE pathogens, a group of bacteria responsible for a large number of hospital-acquired infections and known fo...

Abstract Bone defects present significant challenges in clinical practice due to the limitations of traditional treatments. Compared to traditional cell therapies, exosome-based therapies have emerged as a promising alte...

Transient hypoxia in pregnancy stimulates a physiological reflex response that redistributes blood flow and defends oxygen delivery to the fetal brain. We designed the present experiment to test the hypotheses that trans...

Abstract The world is off track six years to the 2030 deadline for attaining the sustainable development goals and universal health coverage. This is particularly evident in Africa’s armed conflict-affected and humanit...

ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically inter...

Reliable low-latency delivery over satellite downlinks remains fundamentally constrained by long propagation delays, burst-correlated packet loss, and the limited effectiveness of retransmission-based recovery. Although ...

Objectives: The minimum intervention oral health care (MIOC) delivery framework shifts restorative dentistry from a predominantly operative, procedure-centred model towards a person-focused, prevention-oriented and tooth...

Abstract Background Chronic obstructive pulmonary disease (COPD) is a complex, progressive condition associated with substantial physical, psychological, and social burden. Holistic, person-centered care is central to ef...