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Chronic limb-threatening ischemia (CLTI) represents the most severe form of peripheral artery disease, with high risks of infection, tissue loss, amputation, and mortality. Continuous or high-frequency monitoring could i...

IntroductionMatrix stiffening during idiopathic pulmonary fibrosis (IPF) creates a mechanically altered microenvironment that promotes fibroblast activation, yet the metabolic consequences of these mechanical cues remain...

Two anatomically and functionally distinct populations of periodontium-derived fibroblasts can be identified: gingiva fibroblasts (GFs), which originate from the soft connective tissue of the gingiva and support epitheli...

This study investigates whether remodeling/enhancing the two vital proteins—hemoglobin and B3p—in erythrocytes with artificial interference can rejuvenate aged and damaged erythrocytes. Using Raman spectroscopy and S...

Subchondral bone H-type angiogenesis and increased permeability are critical in osteoarthritis (OA) progression, yet the underlying regulatory mechanisms remain unclear. This study utilized proteomic analysis to identify...

Exosomes, as key mediators of intercellular communication, play a central regulatory role in cellular physiological and pathological processes through their dynamic interaction with the cytoskeleton. The cytoskeleton is ...

Cu, a common essential trace element in the human body, is involved in multiple physiological and pathological processes. Cuproptosis, a recently proposed form of cell death, is triggered by Cu overload. It primarily tar...

ObjectiveTo investigate the interaction effects of anti-Müllerian hormone (AMH), antral follicle count (AFC), basal follicle-stimulating hormone (FSH), and endometrial thickness on the outcomes of assisted reproductive ...

BackgroundTherapeutic vulnerability in gastric cancer is profoundly influenced by the tumor microenvironment (TME), yet reliable and clinically actionable preoperative indicators remain insufficient.MethodsWe developed a...

Human blastocyst-derived, pluripotent cell lines are described that have normal karyotypes, express high levels of telomerase activity, and express cell surface markers that characterize primate embryonic stem cells but ...

Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a poo...

Somatic cell nuclear transfer allows trans-acting factors present in the mammalian oocyte to reprogram somatic cell nuclei to an undifferentiated state. We show that four factors (OCT4, SOX2, NANOG, and LIN28) are suffic...

We describe a series of stages for development of the embryo of the zebrafish, Danio (Brachydanio) rerio. We define seven broad periods of embryogenesis--the zygote, cleavage, blastula, gastrula, segmentation, pharyngula...

A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was generated over 9 months fr...

Materias / palabras clave: cell science, developmental biology, experimental biology, cell biology, animal physiology; Science: Biology (General)

Materias / palabras clave: cell biology, developmental biology, molecular biology, biochemistry, immunology, microbiology; Science: Biology (General)

Materias / palabras clave: developmental biology, reproductive medicine; Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy; Medicine: Internal medicine: Specialties of internal medicine: Diseases of the e...

Materias / palabras clave: ecology, biodiversity, evolutionary biology, phylogenetics, palaeontology, developmental biology; Science: Biology (General): Ecology; Science: Biology (General): Evolution

Materias / palabras clave: respiratory tract anatomy, biology, developmental biology, toxicology, pathology; Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system; Science: Human anatomy

Materias / palabras clave: molecular biology, cell biology, life sciences, developmental biology; Science: Biology (General)

Materias / palabras clave: human reproduction, reproductive medicine, embryology, infertility, developmental biology; Medicine: Gynecology and obstetrics; Science: Biology (General): Reproduction

Materias / palabras clave: biochemistry, protein science, cell biology, stem cells, human genetics, developmental biology; Science: Biology (General): Cytology; Science: Physiology: Animal biochemistry

Materias / palabras clave: developmental biology, hydrobiology, animal and plant biology, biotechnology, biochemistry and molecular biology, physiology; Science: Biology (General): Genetics; Science: Biology (General): Reproduction; Science: Physi...

Materias / palabras clave: developmental biology, cellular biology, biotechnology in health care; Medicine: Medicine (General); Science: Biology (General)