Buscar recursos académicos

Materias / palabras clave: Population stratification; Spurious relationship; Biology; Principal component analysis; Allele frequency; Genetic association; Genome-wide association study; Population; Evolutionary biology; Computational biology; Geno...

The many functional partnerships and interactions that occur between proteins are at the core of cellular processing and their systematic characterization helps to provide context in molecular systems biology. However, k...

TopHat is a popular spliced aligner for RNA-sequence (RNA-seq) experiments. In this paper, we describe TopHat2, which incorporates many significant enhancements to TopHat. TopHat2 can align reads of various lengths produ...

Bowtie is an ultrafast, memory-efficient alignment program for aligning short DNA sequence reads to large genomes. For the human genome, Burrows-Wheeler indexing allows Bowtie to align more than 25 million reads per CPU ...

A framework is developed to explore the connection between effective optimization algorithms and the problems they are solving. A number of "no free lunch" (NFL) theorems are presented which establish that for any algori...

The particle swarm is an algorithm for finding optimal regions of complex search spaces through the interaction of individuals in a population of particles. This paper analyzes a particle's trajectory as it moves in disc...

Computational evolutionary biology, statistical phylogenetics and coalescent-based population genetics are becoming increasingly central to the analysis and understanding of molecular sequence data. We present the Bayesi...

A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was generated over 9 months fr...

A tandem repeat in DNA is two or more contiguous, approximate copies of a pattern of nucleotides. Tandem repeats have been shown to cause human disease, may play a variety of regulatory and evolutionary roles and are imp...

A new method called the neighbor-joining method is proposed for reconstructing phylogenetic trees from evolutionary distance data. The principle of this method is to find pairs of operational taxonomic units (OTUs [= nei...

Summary 1. Here, I present a new, multifunctional phylogenetics package, phytools, for the R statistical computing environment. 2. The focus of the package is on methods for phylogenetic comparative biology; however, it ...

Materias / palabras clave: Hamilton–Jacobi equation; Algorithm; Curvature; Mathematics; Mean curvature flow; Function (biology); Conservation law; Mean curvature; Mathematical analysis; Geometry; Evolutionary biology; Biology

Evolutionary computation (EC) has been recently recognized as a research field, which studies a new type of algorithms: Evolutionary Algorithms (EAs). These algorithms process populations of solutions as opposed to most ...

Understanding the evolutionary history of living organisms is a central problem in biology. Until recently the ability to infer evolutionary relationships was limited by the amount of DNA sequence data available, but new...

Materias / palabras clave: computational intelligence, artificial intelligence, machine learning, computer applications, distributed intelligent systems, evolutionary computation; Science: Mathematics: Instruments and machines: Electronic computer...

Materias / palabras clave: artificial intelligence, machine learning, computer vision, computational intelligence, information engineering, evolutionary computation; Science: Mathematics: Instruments and machines: Electronic computers. Computer sc...

Materias / palabras clave: intelligent systems, machine learning, neural computing, evolutionary computation, fuzzy systems, intelligent control and robotics; Science: Science (General): Cybernetics; Science: Mathematics: Instruments and machines:...

Materias / palabras clave: evolutionary computation, soft computing, neural networks, fuzzy logic, optimization, bio-inspired robotics; Science: Mathematics: Instruments and machines: Electronic computers. Computer science

Materias / palabras clave: bioinformatics, computational biology, systems biology, molecular biology, evolutionary biology; Science: Biology (General)

Materias / palabras clave: genome sequencing and analysis, functional genomics, comparative and evolutionary genomics, bioinformatics and computational genomics, regulatory and epigenomic genomics, genomic methods and technology development; Scien...

Materias / palabras clave: fuzzy logic, neural networks, evolutionary and bio-inspired computation, learning theory, probability theory, hybrid methods; Technology: Technology (General): Industrial engineering. Management engineering: Information ...