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Abstract Background Physical exercise has emerged as a promising non-pharmacological approach for improving cognitive and physical function in older adults with mild cognitive impairment (MCI). However, most existing int...

Abstract Background Frailty, social isolation, loneliness, and poverty may render older adults vulnerable to social or health stressors. It is imperative to identify effective interventions to address them especially in ...

Abstract Sarcopenia, the age-related muscle atrophy, is a serious concern as it is associated with frailty, reduced physical functions, and increased mortality risk. Protein supplementation is essential for preserving mu...

BackgroundKinesiophobia is a significant psychological factor that affects early ambulation in postoperative patients. It is particularly common after radiofrequency ablation for atrial fibrillation. Nonetheless, few stu...

BackgroundCholangiocarcinoma (CCA) carries a dismal prognosis. Beyond clinical determinants, socioeconomic deprivation may also influence outcomes. Busan, a rapidly aging metropolitan area in Korea, provides a critical s...

Abstract Introduction The geriatric population is the fastest-growing age group and accounts for one-third of surgical patients. A growing body of evidence reveals that postoperative cognitive dysfunction (POCD) is the m...

Abstract Intrinsic capacity is a concept established by the World Health Organization (WHO). The concept aims to represent the total of a person’s physical and mental abilities, measured across five domains: cognition,...

Background: Adults aged 75 years and older carry the highest absolute risk of cardiovascular disease (CVD) yet remain substantially underrepresented in randomized trials evaluating statin therapy for primary prevention. ...

ABSTRACT Background Physical exercise is recommended for sarcopenia prevention and treatment. Patients with frailty often show poor tolerance. To achieve universal availability, electrical stimulation of skeletal muscles...

Abstract Background Diabetes is associated with a high incidence of diabetic foot and peripheral artery disease and with markedly increased lifetime amputation risk. Here we investigated predictors of reamputation risk a...

Chen Luo,1,2 Yuhan Jiang,1,2 Huiling Yan,2 Kan Sun,3 Wentao Li,3 Mengqing Cao,2 Lijun Zhu,2 Xing Hu,2 Juan Tong,2 Changcheng Zheng1– 3 1Department of Internal Medicine, Graduate School of WanNan Medical College, Wuhu, ...

Abstract N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic mRNA and plays a crucial role in post-transcriptional gene regulation. Recent studies have revealed that m6A modification is dysr...

Abstract Lebanon is frequently referred to as a model of a plural and stable democracy in the Middle East: a multi-ethnic and pluri-religious society that guarantees political representation through a power-sharing confe...

Abstract Background Sarcopenia, altered bone and systemic metabolism, physical frailty and cognitive decline are age-dependent and interrelated phenomena. Sleep disorders which are erroneously considered as part of the a...

Ageing, immobilization, sepsis or cachexia reduce muscle mass and function. The age-related loss, i.e. sarcopenia, contributes to frailty and results in a loss of mobility and autonomy in aging and disease. Affected ind...

ObjectiveThe prognostic implications of surgical outcomes in older adults with ovarian cancer remain unclarified. This study aimed to describe temporal trends in surgical management and examine the association between su...

BACKGROUND: Most older adults prefer to age in place, and supporting older adults to remain in their own homes and communities is also favored by policy makers. Technology can play a role in staying independent, active a...

The European Working Group on Sarcopenia in Older People (EWGSOP) developed a practical clinical definition and consensus diagnostic criteria for age-related sarcopenia. EWGSOP included representatives from four particip...

Materias / palabras clave: geriatrics, aging, gerontology, frailty, elderly; Medicine: Internal medicine: Special situations and conditions: Geriatrics