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Abstract Background The last two decades have seen a significant decrease in mortality for children

Abstract An 8-year-old girl presented with vaginal bleeding without puberty signs. During investigation at 10 years old, the patient presented with advanced bone age, prepubertal hormone levels and internal genitalia. Hy...

BackgroundCongenital athymia (CA) is a rare T cell immune deficiency, fatal without curative treatment with allogeneic processed thymus tissue–agdc (RETHYMIC) implantation (here termed CTTI). The rate and extent of T c...

Nesta revisão foi quantificada a ocorrência da desnutrição infantil em pré-escolares dos diferentes ecossistemas do Amazonas na última década. Foram incluídos os trabalhos que adotaram como parâmetro diagnóstic...

Abstract Naturally, neonates as well as infants in the society are the most susceptible health effects of malnutrition and heavy metal risks due to their inevitable rapid development of their organs and tissues for prope...

Introduction: Retroperitoneal ciliated foregut cysts are a rare developmental anomaly arising from abnormal budding of the primitive foregut, with only a few cases documented in the literature. Case presentation: A 5-mon...

Primary immune regulatory disorder (PIRD) is a subset of inborn errors of immunity (IEIs) caused by disruption of genes involved in regulating the immune response. PIRDs are predominantly characterized by dysregulated im...

Abstract Background The complex relationship between the gut microbiome and immune system development during infancy is considered a key factor in the rising rates of pediatric allergic diseases. Food protein-induced all...

Growth and development of infants are crucial aspects that need to be regularly monitored, with height and weight serving as key indicators of nutritional status. This study aims to design and develop a technology-based ...

Background and Objectives: Proper feeding practices of children less than 2 years of age is important because it is the most critical period of life for optimal growth and development. This study aims to use the newly ...

Neonatal seizures are most commonly attributed to hypoxic-ischaemic injury, metabolic abnormalities, or central nervous system infections; however, an increasing proportion of cases are recognised to have an underlying g...

Background and purposeWe observed that some late-term fetal prenatal magnetic resonance imaging (MRI) scans revealed normal brain structures but exhibited diffuse hyperintense signals on T2-weighted imaging (T2WI) in the...

The signaling pathways that control embryonic development and migration of gonadotropin-releasing hormone (GnRH) neurons, as well as the postnatal fate and function of differentiated cells, are the subject of ongoing res...

ObjectiveThis study examined whether caregivers’ picture book reading styles involving moral narratives are associated with the strength of their belief in a just world.MethodsWe investigated the relationship between c...

This article contributes towards the debate about the dichotomy between care providing and educating that continues to reign in the in the conceptions of nursery school professionals. The article emphasizes care provisio...

Background Parental knowledge of newborn care is essential, as it can influence the newborn’s health, growth, and development. It is challenging due to a lack of mothers’ knowledge and skills, insufficient resources,...

Abstract Background Identification of risk and protective factors for canine visceral leishmaniasis (CVL) is essential to understand the epidemiology of the disease and direct prevention and control strategies. Building ...

OBJETIVO: identificar os fatores obstétricos e neonatais associados ao desfecho de displasia broncopulmonar em pacientes com amniorrexe prematura no pré-termo. MÉTODOS: foram analisados 213 prontuários do Instituto F...

Abstract Background Polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome is a rare autosomal recessive mTORopathy caused by biallelic STE20‐related kinase adaptor alpha (STRADA) loss‐of‐function...

Abstract Background Breastfeeding is an unrivaled way of providing ideal food for healthy growth and development of infants. However, as important as breastfeeding is for the child’s health, it can affect the mother’...

Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease in preterm infants and is characterized by aberrant late-stage lung development driven by multiple factors. Although previous studies have demonstr...

Abstract Background Iodine plays a critical role in producing thyroid hormones essential for brain development. An imbalance of iodine, whether deficiency or excess, can disrupt thyroid function. Iodine-induced hypothyro...

Abstract Background Vertical transmission is the main mode of acquisition of HIV infection in the Democratic Republic of Congo (DRC). We aimed to determine the factors associated with the serological status of mothers an...

BackgroundPyrethroid pesticides (PYRs) can cross the placental barrier to cause intrauterine fetal exposure, which may lead to developmental immunotoxicity (DIT). However, the specific effect of maternal PYR exposure dur...